專利名稱：微生物鑒定的制作方法
技術(shù)領(lǐng)域：
本發(fā)明涉及微生物的鑒定，特別是不同細(xì)菌菌株的區(qū)分。
微生物的準(zhǔn)確鑒定費時且復(fù)雜。由于具有抵抗抗生素性質(zhì)的細(xì)菌株出現(xiàn)，目前開始需要對不同細(xì)菌株進(jìn)行快速且準(zhǔn)確的鑒定，從而能夠產(chǎn)生對付不同細(xì)菌株的適當(dāng)方法。區(qū)分一種細(xì)菌的不同株是非常困難的過程。應(yīng)用基于表型性質(zhì)的典型方法，人們已經(jīng)對區(qū)另不同的細(xì)菌株進(jìn)行了嘗試?？咕V方法利用每一菌株抵抗抗生素的差異性來試圖區(qū)分不同菌株。噬菌體分型法通過病毒感染來辨別細(xì)菌。
然而，雖然上述方法可以依據(jù)一系列表型性質(zhì)對細(xì)菌進(jìn)行分類，但是這些方法對于鑒別具有幾乎相同遺傳組成的不同屬或不同株細(xì)菌不很有效。生物分型法被用來試圖提供所要求的鑒別。該方法研究諸如不同菌株之間毒素產(chǎn)生及色氨酸依賴性的差異。但即使在菌株從不同病人身上得到及交叉感染發(fā)生時，該方法也經(jīng)常無法識別菌株。
追蹤交叉感染源在諸如醫(yī)院等場所是至關(guān)重要的，在這些場所交叉感染可引起嚴(yán)重的健康問題。正確分辨有機體株系對于預(yù)防進(jìn)一步的感染及治療被感染者極為重要。目前出現(xiàn)了抗Methycillin的金黃色葡萄球菌，對于該菌的許多株不能利用噬菌體分型方法來進(jìn)行鑒別；在這種情形下，正確分辨它們便顯得特別重要。
對于分枝桿菌的分析提出了特殊問題。諸如結(jié)核分枝桿菌等的致病型其生長一般較為緩慢，利用傳統(tǒng)方法對其進(jìn)行準(zhǔn)確鑒定可長達(dá)數(shù)周。然而，結(jié)核分枝桿菌的早期鑒定對于控制病人中的感染至為重要。目前鑒定分枝桿菌的方法是對衍生的霉菌酸和細(xì)胞壁脂類進(jìn)行色譜分析。但該方法需要大量的細(xì)菌培養(yǎng)物以便于提取和衍生步驟的進(jìn)行。
聯(lián)合應(yīng)用高溫分解質(zhì)譜(Py-MS)，氣相色譜質(zhì)譜(GC-MS)以及快原子轟擊質(zhì)譜(FAB-MS)進(jìn)行鑒別已在微生物學(xué)的許多領(lǐng)域得到應(yīng)用。但是這些方法要求在分析前進(jìn)行復(fù)雜的樣品制備及提取過程。此外，它們要求有經(jīng)驗的專業(yè)儀器操作者，這使得微生物學(xué)者依賴具有這樣設(shè)施和人員的外部實驗室。
Hillenkamp等于1991年在《分析化學(xué)》第63卷第1193A至1202A頁上報道了基體輔助激光解吸電離質(zhì)譜方法(MALDI-TOF-MS)在分析生物聚合體上的應(yīng)用。
Cotter在1992年《分析化學(xué)》第64卷第1027A至1039A頁上報道了飛行時間質(zhì)譜在生物分子結(jié)構(gòu)分析上的應(yīng)用。
目前需要一種快速，準(zhǔn)確鑒別有機體的方法，該方法可以區(qū)分通常難以分析的不同菌株。
申請人已經(jīng)發(fā)現(xiàn)利用基體輔助激光解吸電離飛行時間質(zhì)譜方法(MALDI-TOF-MS)所得到的微生物質(zhì)譜數(shù)據(jù)依賴于所涉及的微生物分子結(jié)構(gòu)。因此，事實上這樣的數(shù)據(jù)是所研究微生物的“指紋”。當(dāng)一微生物發(fā)生變化時，它的基體輔助激光解吸電離飛行時間質(zhì)譜數(shù)據(jù)將隨之產(chǎn)生改變以反映該微生物結(jié)構(gòu)或組分的改變。
因此，本發(fā)明一方面提供了鑒定微生物的一種方法，其特征為:
對一系列已知微生物，建立了基體輔助激光解吸電離飛行時間質(zhì)譜數(shù)據(jù)庫。
制備未鑒定微生物樣品并獲取基體輔助激光解吸電離飛行時間質(zhì)譜數(shù)據(jù)。
利用適當(dāng)?shù)谋容^方法，將按上述方法獲得的質(zhì)譜數(shù)據(jù)與數(shù)據(jù)庫進(jìn)行比較，以辨認(rèn)出何種已知微生物具有相同或相似質(zhì)譜數(shù)據(jù)。
本發(fā)明的另一方面提供了篩選微生物的裝置，其特征在于該裝置包括:
產(chǎn)生微生物樣品的基體輔助激光解吸電離飛行時間質(zhì)譜數(shù)據(jù)的裝置。
包括一系列微生物的基體輔助激光解吸電離飛行時間質(zhì)譜數(shù)據(jù)的數(shù)據(jù)庫裝置。
本發(fā)明能夠快速鑒定微生物并且無需至今為止所采用的耗費大量勞動的步驟。
基體輔助激光解吸電離飛行時間質(zhì)譜是一高效的質(zhì)譜工具，可以由非專家進(jìn)行操作。進(jìn)一步而言，進(jìn)行分析所需的設(shè)備相對并非昂貴。本發(fā)明的方法和/或裝置使用干燥的，固體樣品；這類樣品易于處理和保存；本發(fā)明可在寬廣的質(zhì)譜范圍對這類樣品進(jìn)行分析。
分析前，微生物可以用傳統(tǒng)方法進(jìn)行培養(yǎng)，例如，在一營養(yǎng)瓊脂板上培養(yǎng)。
質(zhì)譜樣品可按以下方法制備:將微生物細(xì)胞從諸如培養(yǎng)基中取出并直接放入一樣品盤上，然后加入基體。另一制備方法是在放入樣品盤之前，將細(xì)胞與基體混合以保存細(xì)胞的完整性。
使用激光的能量轟擊干燥的基體樣品混合物以產(chǎn)生各種氣相離子形式，然后將其通過脈沖輸送至飛行管內(nèi)。正負(fù)離子均可產(chǎn)生并進(jìn)行鑒定。
各種離子形式可用它們的質(zhì)量電荷比(m/z)來鑒定，其分析精度可優(yōu)于0.1％。每一質(zhì)譜峰的質(zhì)荷比值可由對應(yīng)于特定M+H離子(正離子方式)平均分子量的峰中心確定。
在本發(fā)明的另一方面，通過激光對樣品的多次轟擊來獲取未鑒定微生物的質(zhì)譜數(shù)據(jù)。優(yōu)選地，激光能量轟擊樣品的位置在不同轟擊時在樣品上是變化的。以此方式通過將每次轟擊所得到的質(zhì)譜相加和/或排除與合理值具有較大統(tǒng)計偏差的數(shù)據(jù)，可以減少樣品異質(zhì)性效應(yīng)。這種多次轟擊技術(shù)可有助于獲得準(zhǔn)確，可重復(fù)的質(zhì)譜數(shù)據(jù)。優(yōu)選地，質(zhì)譜數(shù)據(jù)從樣品上的每一個轟擊點獲得，且從每個點采集。
在樣品量有限的情況下，可以使用線性分析器來增強數(shù)據(jù)的靈敏度。
本申請的發(fā)明人發(fā)現(xiàn):對于一種微生物，MALDI-TOF-MS產(chǎn)生獨特的質(zhì)譜數(shù)據(jù)，這使得對微生物的不同屬甚至不同株可以進(jìn)行鑒定和區(qū)分。
由于MALDI-TOF-MS方法需要的樣品量很少，可在數(shù)分鐘內(nèi)完成分析且不需要分離步驟，本發(fā)明亦可用于分析分枝桿菌。
本發(fā)明的另一方面，數(shù)據(jù)庫中所編輯的質(zhì)譜數(shù)據(jù)記錄成強度與質(zhì)荷比曲線的圖形表示。
質(zhì)譜數(shù)據(jù)可以數(shù)字或模擬形式記錄成圖形，數(shù)值或電子格式。質(zhì)譜數(shù)據(jù)可優(yōu)選地記錄在計算機或計算機網(wǎng)絡(luò)存貯介質(zhì)上。存貯介質(zhì)可以是磁介質(zhì)，如軟盤，磁帶或硬盤。此外，存貯介質(zhì)可以是光學(xué)介質(zhì)，如CD-ROM或激光盤。在另一實施方案中，存貯介質(zhì)可以是ROM芯片。
質(zhì)譜數(shù)據(jù)優(yōu)選地存貯為一系列質(zhì)譜比，每一比值對應(yīng)于質(zhì)譜數(shù)據(jù)中峰的中心位置。通過僅存貯質(zhì)荷比，就存貯了鑒定和/或辨認(rèn)微生物所需的最少數(shù)據(jù)。
為了方便檢索和鑒定過程，質(zhì)譜數(shù)據(jù)可分為對應(yīng)于微生物屬的若干組，組以下的劃分則對應(yīng)于微生物的株。
在所分析的質(zhì)譜不能用來進(jìn)行鑒定時，可以將該譜存入數(shù)據(jù)庫以備將來的應(yīng)用。
在數(shù)據(jù)庫存放在計算機的存貯介質(zhì)中時，可以使用所提供的軟件對未能鑒定的質(zhì)譜數(shù)據(jù)進(jìn)行篩選。
該軟件可以通過手工輸入或優(yōu)選地直接從質(zhì)譜儀執(zhí)行獲取和存貯未鑒定微生物質(zhì)譜數(shù)據(jù)，將其與數(shù)據(jù)庫中已鑒定的數(shù)據(jù)進(jìn)行比較并指出何出發(fā)現(xiàn)了匹配或失配。
在一實施方案中，數(shù)據(jù)庫可以包括根據(jù)一微生物所在的屬分組的質(zhì)譜數(shù)據(jù)，軟件將執(zhí)行檢索步驟，這包括首先比較質(zhì)譜數(shù)據(jù)以確定未鑒定細(xì)菌的屬，然后確定細(xì)菌的株。在數(shù)據(jù)庫中存貯大量質(zhì)譜數(shù)據(jù)時，上述檢索方式使檢索過程最佳化，提高檢索效率。
軟件可以允許未辨認(rèn)的質(zhì)譜數(shù)據(jù)存在校準(zhǔn)誤差，利用數(shù)據(jù)庫中的相應(yīng)數(shù)據(jù)可以鑒別未鑒定質(zhì)譜的趨勢(如質(zhì)譜中相鄰峰之間的質(zhì)荷比差)，無需利用數(shù)據(jù)的絕對值。
計算機可以被包括在MALDI-TOF-MS質(zhì)譜儀中，于是質(zhì)譜數(shù)據(jù)可直接從探測器轉(zhuǎn)輸至計算機以供分析。
在另一方案中，計算機可與質(zhì)譜儀分開并以遠(yuǎn)程方式聯(lián)接。
本發(fā)明亦包括微生物質(zhì)譜數(shù)據(jù)庫。該庫含通過用于本發(fā)明的方法或裝置的MALDI-TOF-MS分析所獲得的每一微生物質(zhì)譜數(shù)據(jù)。
下面僅通過舉例并且參照實施本發(fā)明的方法的附圖進(jìn)行說明。


圖1為從樣品SA，CF和ECC2中所獲得的部分質(zhì)譜。
圖2為質(zhì)荷比在500至1500 Da之間的恥垢分枝桿菌正離子形式的部分質(zhì)譜圖。所列出峰A-K中的每一個表示可能的mycoserates異位形式。相對峰高與存在于每一分子量處的異位種類數(shù)目相關(guān)。用字母表示的峰，分子量，以及一種可能的異位結(jié)構(gòu)列出如下:
A:1156,Ⅰ18Ⅱ18Ⅲ2Ⅳ2Ⅴ14B:1170,Ⅰ17Ⅱ17Ⅲ3Ⅳ2Ⅴ14C:1184,Ⅰ15Ⅱ16Ⅲ4Ⅳ2Ⅴ14D:1198,Ⅰ18Ⅱ18Ⅲ3Ⅳ2Ⅴ14E:1212,Ⅰ17Ⅱ17Ⅲ4Ⅳ2Ⅴ14F:1226,Ⅰ16Ⅱ16Ⅲ5Ⅳ2Ⅴ14G:1240,Ⅰ18Ⅱ16Ⅲ4Ⅳ2Ⅴ14H:1254,Ⅰ17Ⅱ17Ⅲ5Ⅳ2Ⅴ14I:1268,Ⅰ17Ⅱ17Ⅲ5Ⅳ2Ⅴ15J:1282,Ⅰ18Ⅱ18Ⅲ5Ⅳ2Ⅴ14K:1296,Ⅰ18Ⅱ18Ⅲ5Ⅳ2Ⅴ15上述引用的分子量適用于單同位素分子離子(M)。
在下面的例子中，分析了10種微生物并得到了它們的MALDI-TOF-MS質(zhì)譜數(shù)據(jù)。這些微生物為
上述10種微生物中的每一種均傳代培養(yǎng)于兩個分開的瓊脂營養(yǎng)板上。每對在37℃下分別溫育3天和6天。
對于分析而言，一單獨、可見的細(xì)胞群落是足夠的，可以用無菌環(huán)將細(xì)胞群落從瓊脂板上取出。所有樣品在基體α-氰基-4-羥基肉桂酸(α-CHCA)中進(jìn)行分析?；w溶解于水、乙醇和乙腈的混合物(比例1∶1∶1)中，微生物在50-100μl的基體溶液中乳化。
然后1μl等分樣品加入樣品激光耙位并在分析前使其干燥。利用KRATOSTMKompact MALOI Ⅲ飛行時間質(zhì)譜儀，對樣品進(jìn)行MALDI分析。應(yīng)用輸出波長為337nm、脈沖寬度為3ns的氮分子激光對樣品進(jìn)行離子化。激光強度設(shè)置為剛好高于離子產(chǎn)生閾值。使用+20KV的加速電壓并在正離子探測方式下，操作質(zhì)譜儀。使用線性和反射分析器分析樣品。所使用的探測器由與電子放大器相連的分立倍增電極組成。
對每一微生物的每對樣品進(jìn)行分析，得到質(zhì)譜數(shù)據(jù)。圖1表示SA,CF和ECC2的質(zhì)譜。從圖中可以清楚地看到來自每一微生物的各種離子種類所產(chǎn)生的質(zhì)譜峰分布的差異。所產(chǎn)生的質(zhì)譜構(gòu)成獨特的“指紋”，利用這種“指紋”可以對微生物進(jìn)行種間和株間鑒別。利用質(zhì)譜特征的相似性可以對質(zhì)譜根據(jù)微生物的屬進(jìn)行編組。
圖2為恥垢分枝桿菌正離子質(zhì)譜，該譜顯示1150-1300 Da范圍內(nèi)令人感興趣的譜峰形式。以前對該微生物的細(xì)胞壁提取物的分析表明上述這些峰代表細(xì)胞壁內(nèi)的霉菌酸或相關(guān)脂類。上述數(shù)據(jù)可能與屬結(jié)核菌醇類的dimycocerosates相關(guān)。該物質(zhì)為非共價鍵結(jié)合且在混合過程中可能被抽提至基體中。對mycoserates所提出的結(jié)構(gòu)可參見圖2的說明。
表1對所有檢查過的微生物列出了部分m/z值。<
表1中的前4列列出了在1058-1852 Da范圍內(nèi)4種大腸桿菌培養(yǎng)物質(zhì)譜峰的m/z比值。黑體數(shù)字表示的峰存在于所有被測大腸桿菌株(1102,1231,1316,1360,1489和1618)中。因此從這些譜峰的存在可以鑒定大腸桿菌屬。
通過其它峰的存在與否可鑒定不同的株。
例如，ECN在1852位置處具有一個峰，這區(qū)別于ECC1和ECC2。ECK在1852位置處亦有一個峰，但通過它在1058和1187位置處的兩個峰，可以對其進(jìn)行鑒別。
與大腸桿菌密切相關(guān)的其它菌種為CF和KA。它們與大腸桿菌在1102,1231、1360,1489,1618位置處均具有峰值，但是CF和KA在1316位置處沒有峰，而大腸桿菌在此處具有特征峰，因而可以對CF和KA進(jìn)行區(qū)分。通過比較750,751,1314,1445,1480,1575,1582和1876處峰的存在與否可區(qū)分CF和KA。
利用質(zhì)譜峰的質(zhì)荷比表示的質(zhì)譜為每一微生物提供了“指紋”。這種指紋對屬間和株間差異性均靈敏。這樣的指紋數(shù)據(jù)庫提供了快速篩選樣品以鑒定所存在的微生物株的方法。該方法在醫(yī)學(xué)微生物學(xué)領(lǐng)域具有重要應(yīng)用，但在需要準(zhǔn)確而且迅速鑒定微生物的許多其它領(lǐng)域亦將得到應(yīng)用。
對于以下微生物，建立了MALDI-TOF-MS質(zhì)譜數(shù)據(jù)庫大腸桿菌8110大腸桿菌10214 K12 λ產(chǎn)氣克雷伯氏菌8172弗氏檸檬酸桿菌9750金黃色葡萄球菌B1金黃色葡萄球菌B2抗methicillin的金黃色葡萄球菌(MRSA)01/270030金黃色葡萄球菌(MRSA)02/270238*艱難梭菌NCTC 11204*艱難梭菌NCTC 11206*產(chǎn)氣熒膜梭菌*破傷風(fēng)梭菌瑪爾摩分枝桿菌0036C鳥分枝桿菌-intracellulare-scrofulaceum 0352C鳥分枝桿菌-intracellulare 0589C蟾分枝桿菌0545C奈瑟氏球菌M96255506奈瑟氏球菌M96255510
奈瑟氏球菌M97251540奈瑟氏球菌M97251545奈瑟氏球菌M97251682所獲得的質(zhì)譜數(shù)據(jù)如下完整細(xì)胞MALDIKRATOS DB Set大腸桿菌8110Data:std0001.1 24 Jul 97 16:26 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比 峰值(mV) 標(biāo)志510.4 5.700.63 2.21519.4 2.460.27 0.89525.5 5.770.63 1.69530.9 0.710.08 0.49543.4 85.63 9.41 31.16551.7 2.190.24 1.04565.1 56.59 6.22 19.00581.2 16.73 1.84 6.10 U587.3 10.33 1.13 4.32 U603.7 11.79 1.29 5.12609.7 0.970.11 0.37619.6 3.140.35 0.89 U625.5 3.380.37 1.26 U644.0 0.930.10 0.34651.2 0.560.06 0.34657.7 53.23 5.85 21.63 U665.8 24.08 2.65 8.61 U673.8 70.64 7.76 27.18689.6 30.78 3.38 10.75705.8 5.380.59 1.72 U715.4 11.03 1.21 3.16 U728.3 47.11 5.18 15.47736.5 1.990.22 0.70 U744.2 28.91 3.18 9.87 U750.4 31.44 3.45 8.39 U766.5 28.31 3.11 9.01 U774.6 2.150.24 1.07 U782.0 9.741.07 2.63 U791.0 4.090.45 1.23 U794.2 2.510.28 0.74 U812.6 4.930.54 1.04831.9 2.240.25 0.49845.3 4.890.54 1.65853.2 1.370.15 0.37863.8 1.150.13 0.46 U869.9 4.180.46 1.38 U885.0 10.83 1.19 2.85901.1 2.350.26 1.07916.7 1.780.20 0.40932.8 0.640.07 0.34974.5 9.611.06 2.91987.5 3.030.33 0.371004.82.150.24 0.401031.61.800.20 0.371059.72.330.26 0.921080.32.100.23 0.461103.482.79 9.09 29.691119.50.930.10 0.401125.23.660.40 1.291141.41.140.13 0.371147.51.540.17 0.67 U1153.52.150.24 0.67 U1176.11.440.16 0.341188.47.660.84 1.72 U1198.20.790.09 0.43 U1213.31.620.18 0.491232.8100.00 10.99 35.48完整細(xì)胞MALDIKRATOS DB Set大腸桿菌8110Data:std0001.1 24 Jul 97 16:26 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1254.17.58 0.83 2.301270.52.44 0.27 1.13 U1276.62.33 0.26 0.77 U1292.11.91 0.21 0.801314.64.41 0.48 0.891361.956.31 6.19 20.991384.34.47 0.49 1.191400.23.18 0.35 0.861421.80.88 0.10 0.431467.01.72 0.19 0.551490.67.10 0.78 2.211592.50.63 0.07 0.34完整細(xì)胞MALDIKRATOS DB Set大腸桿菌10214 K 121 amData:std0003.3 24 Jul 97 16:28 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志510.68.421.46 2.24519.09.511.65 2.30 U524.444.43 7.70 9.34 U539.428.14 4.87 4.93 U543.1100.00 17.32 21.11 U551.531.48 5.45 7.08564.936.20 6.27 7.05580.910.33 1.79 1.69587.65.941.03 1.47603.77.041.22 1.26609.51.070.19 0.18618.48.021.39 0.77629.50.770.13 0.34640.75.781.00 0.92648.80.430.07 0.21657.728.64 4.96 6.68 U666.032.05 5.55 6.92 U673.828.00 4.85 6.56689.116.38 2.84 3.28706.88.081.40 0.89714.411.31 1.96 2.57729.86.441.12 1.10736.03.090.53 0.67744.41.620.28 0.31752.23.910.68 0.70762.81.480.26 0.40779.90.730.13 0.21788.611.11 1.92 1.32798.40.850.15 0.28801.40.490.08 0.25814.03.490.61 0.46827.01.760.31 0.34833.01.570.27 0.40846.93.840.66 0.67854.92.500.43 0.46863.22.570.44 0.37869.31.090.19 0.25885.38.611.49 0.95895.10.890.15 0.25900.51.530.27 0.37911.01.200.21 0.43921.61.840.32 0.40926.20.910.16 0.21933.61.000.17 0.25955.71.000.17 0.28973.63.900.68 0.58999.71.540.27 0.401015.6 2.620.45 0.281031.0 2.760.48 0.311037.6 0.340.06 0.181044.3 1.040.18 0.211054.1 0.740.13 0.251059.0 1.190.21 0.311065.5 1.370.24 0.281090.6 0.910.16 0.181103.4 10.98 1.90 1.191120.1 2.270.39 0.37 U完整細(xì)胞MALDIKRATOS DB Set大腸桿菌10214 K 121 amData:std0003.3 24 Jul 97 16:28 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1128.71.87 0.32 0.34 U1154.27.75 1.34 1.231174.85.20 0.90 0.641192.70.37 0.06 0.181197.61.04 0.18 0.371232.47.42 1.29 1.501248.40.90 0.16 0.211253.40.41 0.07 0.181272.21.20 0.21 0.311279.31.15 0.20 0.371293.80.73 0.13 0.181313.63.23 0.56 0.341322.91.83 0.32 0.281339.02.00 0.35 0.281361.68.82 1.53 1.531378.43.98 0.69 0.551444.30.60 0.10 0.181453.00.68 0.12 0.251492.14.03 0.70 0.551532.11.29 0.22 0.311545.81.61 0.28 0.211566.71.01 0.18 0.181579.80.63 0.11 0.211638.50.85 0.15 0.181646.10.71 0.12 0.181749.20.44 0.08 0.181904.90.80 0.14 0.251956.31.50 0.26 0.28完整細(xì)胞MALDIKRATOS DB Set產(chǎn)氣克雷氏菌8172Data:std0013.13 24 Jul 97 16:39 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志519.02.34 0.51 1.32524.48.78 1.91 4.35539.23.55 0.77 1.53 U543.44.20 0.91 2.30 U552.03.43 0.75 1.84565.414.24 3.10 4.69575.34.29 0.93 1.47588.00.95 0.21 0.46591.51.58 0.34 0.52600.20.91 0.20 0.49635.70.88 0.19 0.58640.42.45 0.53 0.89651.51.61 0.35 0.80 U658.0100.00 21.77 45.25 U667.71.74 0.38 0.74673.821.48 4.68 10.57 U680.03.42 0.75 1.50 U688.64.25 0.92 1.41705.31.93 0.42 0.67 U710.31.36 0.30 0.89 U714.11.05 0.23 0.49 U727.85.75 1.25 2.36 U736.02.22 0.48 0.61 U750.46.13 1.33 2.48767.32.86 0.62 0.77768.80.58 0.13 0.46774.91.14 0.25 0.67 U778.61.35 0.29 0.67 U782.81.35 0.29 0.67 U790.53.41 0.74 1.04 U795.50.90 0.20 0.74 U803.01.65 0.36 0.74814.84.59 1.00 1.69822.92.02 0.44 0.77830.51.13 0.25 0.86836.02.30 0.50 0.89 U840.61.11 0.24 0.80 U847.53.22 0.70 1.56 U856.31.41 0.31 0.67862.91.22 0.27 0.74 U869.012.21 2.66 5.15 U885.08.97 1.95 1.96911.94.94 1.08 1.56 U923.01.52 0.33 0.70 U927.01.13 0.25 0.70 U933.41.48 0.32 0.61962.71.17 0.26 0.52974.80.91 0.20 0.58986.62.67 0.58 0.83 U991.01.00 0.22 0.58 U1000.0 6.35 1.38 2.451021.9 5.21 1.13 2.54 U1026.7 1.63 0.36 0.58 U1043.7 4.36 0.95 1.231058.7 2.39 0.52 0.551075.1 1.14 0.25 0.74 U1080.7 6.21 1.35 2.85 UKRATOS DB Set產(chǎn)氣克雷氏菌8172Data:std0013.13 24 Jul 97 16:39 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1090.00.83 0.18 0.581096.51.42 0.31 0.67 U1102.22.33 0.51 1.07 U1108.52.92 0.64 1.13 U1117.61.25 0.27 0.43 U1126.80.89 0.19 0.46 U1132.21.55 0.34 0.61 U1153.914.75 3.21 5.361167.00.91 0.20 0.58 U1176.119.08 4.15 9.28 U1192.73.13 0.68 1.10 U1197.99.71 2.11 4.53 U1222.82.64 0.57 0.521231.11.87 0.41 0.461264.82.81 0.61 0.611278.91.50 0.33 0.521291.54.87 1.06 1.56 U1300.61.56 0.34 0.64 U1306.11.05 0.23 0.67 U1310.51.75 0.38 0.64 U1319.10.61 0.13 0.43 U1324.92.69 0.59 0.98 U1339.41.50 0.33 0.74 U1347.41.28 0.28 0.55 U1361.64.44 0.97 1.161376.30.94 0.21 0.431392.14.19 0.91 0.701408.02.67 0.58 0.641437.52.77 0.60 0.55 U1452.23.58 0.78 0.49 U1476.42.28 0.50 0.58 U1491.03.29 0.72 0.74 U1503.01.84 0.40 0.58 U1518.12.36 0.51 0.55 U1538.82.15 0.47 0.49 U1558.84.01 0.87 0.74 U1612.21.28 0.28 0.431620.53.96 0.86 1.501670.30.67 0.15 0.43 U1678.41.62 0.35 0.46 U1706.42.93 0.64 0.95 U1721.62.04 0.44 0.70 U1733.42.17 0.47 0.49 U1750.02.90 0.63 1.01 U1773.72.98 0.65 0.921790.91.91 0.42 0.551853.81.29 0.28 0.461879.04.41 0.96 0.861898.70.81 0.18 0.46 U1927.23.73 0.81 0.52 U1965.13.36 0.73 0.612008.51.83 0.40 0.552084.53.35 0.73 0.462098.71.89 0.41 0.432171.61.55 0.34 0.43 U2191.41.38 0.30 0.492295.21.97 0.43 0.49 U完整細(xì)胞MALDIKRATOS DB Set產(chǎn)氣克雷氏菌8172Data:std0013.13 24 Ju1 97 16:39 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2388.81.10 0.24 0.432402.20.67 0.15 0.43完整細(xì)胞MALDIKRATOS DB Set弗氏檸檬酸桿菌9750Data:std0015.15 24 Jul 97 16:42 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志502.10.20 0.02 0.21510.43.46 0.42 1.35518.818.83 2.29 5.73 U524.442.51 5.18 13.63 U539.621.22 2.58 7.20 U543.622.28 2.71 7.11 U551.572.69 8.85 21.66 U565.425.50 3.11 5.42 U569.65.12 0.62 2.67 U578.920.95 2.55 4.53588.95.04 0.61 2.14600.51.21 0.15 0.61604.65.22 0.64 1.29612.11.30 0.16 0.70618.67.82 0.95 2.57 U623.16.21 0.76 1.56 U630.20.40 0.05 0.31640.712.45 1.52 2.94653.11.19 0.14 0.40657.721.56 2.63 8.06667.913.93 1.70 3.80 U673.819.62 2.39 6.99 U684.11.28 0.16 0.61690.18.93 1.09 1.81707.63.80 0.46 1.13 U714.69.49 1.16 2.79 U729.68.59 1.05 1.99736.21.94 0.24 0.92742.13.15 0.38 0.70752.45.57 0.68 1.90762.66.06 0.74 1.87 U768.13.05 0.37 1.13 U774.40.87 0.11 0.43 U778.81.43 0.17 0.58 U784.61.80 0.22 0.77 U789.15.22 0.64 1.10 U796.01.62 0.20 0.55 U803.50.52 0.06 0.31807.50.62 0.08 0.40 U813.24.97 0.60 1.01 U822.42.11 0.26 0.61 U830.24.28 0.52 0.98839.81.45 0.18 0.52847.53.15 0.38 0.92856.02.07 0.25 0.74 U863.24.73 0.58 1.19 U873.20.78 0.09 0.46884.16.27 0.76 1.23 U892.04.42 0.54 0.74 U911.03.61 0.44 0.86929.61.45 0.18 0.34947.32.11 0.26 0.31962.12.03 0.25 0.43969.80.79 0.10 0.31973.90.34 0.04 0.21986.91.46 0.18 0.37991.00.50 0.06 0.21完整細(xì)胞MALDIKRATOS DB Set弗氏檸檬酸桿菌9750Data:std0015.15 24 Jul 97 16:42 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power.60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1000.33.25 0.40 0.671009.00.95 0.12 0.281021.32.00 0.24 0.671029.80.85 0.10 0.371038.90.72 0.09 0.281045.31.02 0.12 0.341051.10.59 0.07 0.311062.71.68 0.21 0.401073.51.14 0.14 0.491090.62.82 0.34 0.701106.33.26 0.40 0.64 U1116.01.01 0.12 0.40 U1133.12.26 0.27 0.461153.93.73 0.45 0.831176.12.95 0.36 0.581182.90.32 0.04 0.211202.51.65 0.20 0.311214.90.83 0.10 0.311263.11.59 0.19 0.431270.50.51 0.06 0.211278.90.98 0.12 0.251292.10.86 0.10 0.371300.30.72 0.09 0.211306.80.68 0.08 0.211331.12.08 0.25 0.311341.10.81 0.10 0.251361.91.29 0.16 0.281379.81.70 0.21 0.281414.40.65 0.08 0.281419.30.59 0.07 0.311451.90.64 0.08 0.251492.44.12 0.50 1.161507.83.16 0.38 0.801531.00.50 0.06 0.251540.60.48 0.06 0.211574.50.65 0.08 0.251621.719.56 2.38 6.53 U1637.713.82 1.68 4.04 U1659.93.22 0.39 1.041679.21.63 0.20 0.401706.80.44 0.05 0.211722.41.34 0.16 0.311750.816.69 2.03 5.76 U1767.012.39 1.51 3.34 U1789.32.05 0.25 0.831804.51.06 0.13 0.281880.72.49 0.30 0.741904.56.29 0.77 0.671926.40.35 0.04 0.211957.60.98 0.12 0.211973.92.15 0.26 0.282010.61.48 0.18 0.432028.01.43 0.17 0.282049.31.23 0.15 0.312070.70.76 0.09 0.212084.10.64 0.08 0.282169.82.29 0.28 0.28完整細(xì)胞MALDIKRATOS DB Set弗氏檸檬酸桿菌9750Data:std0015.15 24 Jul 97 16:42 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2222.52.39 0.29 0.342240.81.03 0.13 0.252256.91.61 0.20 0.342318.74.11 0.50 0.372370.40.88 0.11 0.252414.73.11 0.38 0.282478.21.34 0.16 0.40 U2492.33.51 0.43 0.61 U2542.12.85 0.35 0.342596.12.24 0.27 0.312682.01.48 0.18 0.252708.01.87 0.23 0.282733.61.77 0.22 0.282782.71.00 0.12 0.212816.63.42 0.42 0.312874.51.64 0.20 0.342899.92.48 0.30 0.282946.30.82 0.10 0.252991.11.52 0.19 0.253087.42.11 0.26 0.283162.95.73 0.70 0.893188.42.41 0.29 0.373257.01.81 0.22 0.343400.2100.00 12.18 19.61 U3423.922.22 2.71 3.52 U3501.70.45 0.05 0.213538.72.18 0.26 0.253586.02.16 0.26 0.253627.41.16 0.14 0.283769.81.49 0.18 0.283824.50.63 0.08 0.253874.85.38 0.66 0.553974.81.63 0.20 0.214769.31.88 0.23 0.435451.242.34 5.16 7.357739.53.92 0.48 0.61金黃色葡萄球菌分離物營養(yǎng)瓊脂BIData:a0001.1 17 Jul 97 17:18 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志511.30.88 0.19 0.49 U517.11.64 0.35 0.46 U528.74.06 0.87 1.16543.41.16 0.25 0.52 U558.12.81 0.60 0.80 U563.96.13 1.31 2.51 U580.410.51 2.24 3.80587.30.62 0.13 0.46595.82.29 0.49 0.86 U604.11.57 0.34 0.67 U620.32.24 0.48 1.01 U623.62.19 0.47 0.92 U638.50.70 0.15 0.49 U642.11.71 0.36 0.86 U653.41.93 0.41 0.80 U658.512.16 2.60 5.88 U668.53.09 0.66 1.16 U674.463.67 13.60 30.97 U684.71.25 0.27 0.74 U690.4100.00 21.35 43.78 U706.456.30 12.02 24.42722.45.15 1.10 2.36769.43.13 0.67 0.80785.71.98 0.42 1.13 U791.66.72 1.43 2.85 U801.70.82 0.18 0.52 U807.66.01 1.28 2.33 U823.80.97 0.21 0.77 U827.62.80 0.60 1.13 U832.80.62 0.13 0.58 U847.35.21 1.11 1.81865.94.15 0.89 1.23881.84.72 1.01 2.30 U886.08.92 1.90 4.14 U896.23.32 0.71 2.39 U902.220.09 4.29 8.79 U918.717.72 3.78 6.83934.54.79 1.02 2.39985.50.79 0.17 0.431003.4 4.86 1.04 1.041020.3 5.48 1.17 1.781037.0 3.53 0.75 1.071053.5 1.76 0.38 0.741082.5 2.25 0.48 0.641097.5 3.35 0.71 1.041115.1 8.01 1.71 2.421130.3 6.60 1.41 2.51 U1147.6 4.95 1.06 1.29 U1163.6 1.24 0.27 0.58 U1196.5 0.89 0.19 0.461225.4 2.82 0.60 0.641250.4 4.51 0.96 0.701276.9 1.76 0.38 0.46 U1325.7 4.04 0.86 0.83 U1342.7 3.43 0.73 1.29 U1356.6 3.09 0.66 0.52 U1372.3 2.17 0.46 0.49 U金黃色葡萄球菌分離物營養(yǎng)瓊脂BIData:a0001.1 17 Jul 97 17:18 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1388.10.91 0.19 0.46 U1426.42.40 0.51 0.641458.03.16 0.68 0.611473.21.29 0.28 0.551518.63.02 0.64 0.431534.81.69 0.36 0.551554.91.75 0.37 0.52 U1569.11.68 0.36 0.52 U1827.31.01 0.22 0.551841.91.00 0.21 0.462000.72.13 0.45 0.432100.52.59 0.55 0.432387.01.59 0.34 0.462516.31.38 0.29 0.492814.53.14 0.67 0.46金黃色葡萄球菌分離物營養(yǎng)瓊脂B2Data:a0003.3 17 Jul 97 17:22 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志500.84.74 0.57 1.35 U505.51.19 0.14 0.61512.39.28 1.11 1.62 U516.85.15 0.62 1.29 U526.612.17 1.46 2.67 U530.515.58 1.87 2.57 U543.645.57 5.48 8.52552.91.29 0.16 0.74557.64.15 0.50 1.29 U563.720.99 2.52 4.50 U569.33.81 0.46 1.44575.94.84 0.58 1.16 U581.127.92 3.35 4.14 U596.74.15 0.50 0.77 U603.411.88 1.43 1.59 U620.59.11 1.09 1.93 U622.64.52 0.54 1.78 U625.25.06 0.61 1.62 U635.94.64 0.56 1.10645.26.06 0.73 1.10650.83.37 0.41 0.95 U659.532.49 3.90 5.82 U666.821.15 2.54 4.07 U674.471.60 8.60 17.83684.25.63 0.68 1.44690.4100.00 12.02 22.86706.447.63 5.72 11.64715.30.34 0.04 0.21722.66.47 0.78 1.23731.31.10 0.13 0.49741.61 40 0.17 0.40 U746.54.67 0.56 0.74 U757.40.39 0.05 0.21764.11.45 0.17 0.37772.011.04 1.33 1.78790.522.67 2.72 2.76807.310.23 1.23 1.99 U811.64.49 0.54 1.16 U819.20.26 0.03 0.21827.17.52 0.90 1.23 U833.93.85 0.46 0.95 U846.023.74 2.85 3.98864.26.84 0.82 1.90 U869.25.88 0.71 1.13 U880.44.84 0.58 1.07 U886.09.39 1.13 2.39 U894.22.36 0.28 0.46 U902.419.79 2.38 3.52 U911.03.42 0.41 1.04 U918.48.74 1.05 1.56 U937.14.28 0.51 0.55953.42.61 0.31 0.55963.73.55 0.43 0.49982.94.70 0.56 0.461000.7 3.85 0.46 0.521015.4 2.52 0.30 0.61 U1021.2 3.64 0.44 0.70 U金黃色葡萄球菌分離物營養(yǎng)瓊脂B2Data:a0003.3 17 Jul 97 17:22 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1040.66.18 0.74 0.581053.20.71 0.09 0.211061.50.99 0.12 0.211070.22.25 0.27 0.52 U1078.53.88 0.47 0.40 U1097.85.73 0.69 0.671113.98.46 1.02 1.721131.04.44 0.53 0.701153.75.13 0.62 0.491175.33.44 0.41 0.401191.21.48 0.18 0.281199.40.78 0.09 0.281218.23.15 0.38 0.431233.71.75 0.21 0.401249.04.88 0.59 0.611261.12.27 0.27 0.521278.61.49 0.18 0.341285.12.08 0.25 0.341308.62.33 0.28 0.491324.44.45 0.54 0.701344.02.34 0.28 0.431353.82.56 0.31 0.401373.32.04 0.24 0.401390.61.54 0.18 0.281412.23.31 0.40 0.281428.63.71 0.45 0.341455.92.04 0.24 0.251477.22.82 0.34 0.341483.01.32 0.16 0.211496.90.56 0.07 0.211524.94.16 0.50 0.341536.00.58 0.07 0.211545.22.28 0.27 0.431569.91.05 0.13 0.211599.22.52 0.30 0.281641.51.72 0.21 0.401655.73.84 0.46 0.431712.81.07 0.13 0.281748.22.04 0.25 0.281769.22.08 0.25 0.311793.10.95 0.11 0.211804.41.70 0.20 0.281829.81.86 0.22 0.211870.50.75 0.09 0.211919.01.77 0.21 0.212019.30.74 0.09 0.252057 32.06 0.25 0.402149.71.94 0.23 0.252167.81.76 0.21 0.282184.51.18 0.14 0.312206.20.58 0.07 0.212266.61.16 0.14 0.312451.21.19 0.14 0.252513.90.98 0.12 0.252535.81.35 0.16 0.212779.03.37 0.41 0.312852.81.96 0.24 0.43金黃色葡萄球菌分離物營養(yǎng)瓊脂B2Data:a0003.3 17 Jul 97 17:22 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2868.52.52 0.30 0.462933.21.29 0.16 0.253046.92.07 0.25 0.313093.60.77 0.09 0.253122.11.19 0.14 0.213184.71.45 0.17 0.253248.60.69 0.08 0.213464.44.41 0.53 0.253534.91.34 0.16 0.313552.91.44 0.17 0.255533.12.24 0.27 0.406897.08.05 0.97 0.83完整細(xì)胞MALDIMRSA 01/270030Data:a0001.1 3 Jul 97 17:50 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI2 V5.2.1:+Linear High Power:70.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志502.50.35 0.07 0.12517.90.35 0.07 0.12533.50.29 0.06 0.12536.60.73 0.15 0.18558.70.62 0.13 0.21565.00.44 0.09 0.18581.10.23 0.05 0.12582.20.41 0.09 0.18584.70.35 0.07 0.12596.70.83 0.17 0.15599.90.15 0.03 0.09601.60.15 0.03 0.09622.40.25 0.05 0.12630.40.23 0.05 0.12633.50.12 0.03 0.09637.80.12 0.03 0.09639.50.97 0.20 0.31655.12.49 0.52 0.28659.74.52 0.94 0.83662.60.15 0.03 0.09671.25.70 1.18 0.86 U675.635.98 7.48 5.02 U687.20.89 0.19 0.25691.784.81 17.63 11.40700.70.15 0.03 0.12707.7100.00 20.78 10.78723.630.72 6.38 3.92732.80.58 0.12 0.12753.50.62 0.13 0.12763.91.12 0.23 0.18766.00.06 0.01 0.09767.3o.12 0.03 0.09774.60.77 0.16 0.18777.00.44 0.09 0.18779.60.21 0.04 0.09787.61.47 0.31 0.34792.40.15 0.03 0.09794.00.15 0.03 0.的803.30.79 0.16 0.25813.30.25 0.05 0.12817.30.12 0.03 0.09819.20.15 0.03 0.09824.60.87 0.18 0.18831.40.21 0.04 0.12834.70.54 0.11 0.18846.20.23 0.05 0.12848.20.33 0.07 0.12849.80.91 0.19 0.28855.10.17 0.03 0.12861.70.89 0.19 0.18865.31.62 0.34 0.28871.50.37 0.08 0.15876.20.46 0.09 0.12877.90.23 0.05 0.12881.53.83 0.80 0.46 U887.42.61 0.54 0.58 U897.35.16 1.07 0.77 U完整細(xì)胞MALDIMRSA 01/270030Data:a0001.1 3 Jul 97 17:50 Cal:test 25 Apr 9711:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志903.618.45 3.83 2.24 U913.63.27 0.68 0.67 U919.929.28 6.09 3.09 U926.20.54 0.11 0.18935.722.57 4.69 2.67953.12.30 0.48 0.46955.80.23 0.05 0.09958.40.33 0.07 0.12970.40.21 0.04 0.09977.50.99 0.21 0.18982.90.23 0.05 0.121003.4 0.73 0.15 0.181020.3 0.58 0.12 0.181023.0 0.17 0.03 0.121030.9 0.15 0.03 0.091033.6 0.31 0.06 0.121048.9 0.46 0.09 0.151054.1 0.31 0.06 0.121074.1 1.06 0.22 0.341095.0 0.37 0.08 0.151097.2 2.05 0.43 0.211106.0 0.15 0.03 0.091109.4 1.78 0.37 0.401114.8 5.53 1.15 0.491131.3 14.24 2.96 1.261141.5 0.15 0.03 0.091147.6 7.09 1.47 0.891160.1 0.54 0.11 0.151163.3 2.78 0.58 0.311170.8 2.22 0.46 0.371187.6 0.48 0.10 0.151190.9 0.37 0.08 0.151196.5 0.15 0.03 0.091202.4 0.15 0.03 0.091214.2 0.48 0.10 0.181227.4 0.33 0.07 0.121240.0 0.15 0.03 0.091242.0 0.12 0.03 0.091248.0 0.50 0.10 0.151253.4 0.48 0.10 0.151298.3 0.66 0.14 0.211308.2 0.48 0.10 0.151311.7 0.23 0.05 0.121323.0 0.68 0.14 0.181327.5 3.48 0.72 0.401335.0 0.54 0.11 0.181343.7 7.61 1.58 0.671359.3 4.19 0.87 0.431371.9 0.60 0.12 0.181375.8 5.35 1.11 0.611387.7 0.75 0.16 0.181393.4 1.49 0.31 0.281406.8 1.26 0.26 0.281415.7 1.58 0.33 0.251436.8 2.05 0.43 0.211444.3 1.31 0.27 0.211450.4 0.21 0.04 0.09完整細(xì)胞MALDIMRSA 01/270030Data:a0001.1 3 Jul 97 17:50 Cal:test 25 Apr 97 11:25Kratos Kompact MAIDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1460.90.31 0.06 0.121477.90.41 0.09 0.121502.40.23 0.05 0.121508.60.33 0.07 0.121510.90.44 0.09 0.121513.80.21 0.04 0.091524.50.23 0.05 0.121541.10.48 0.10 0.151546.40.15 0.03 0.091555.30.12 0.03 0.091567.30.21 0.04 0.091571.41.26 0.26 0.251579.61.55 0.32 0.251588.72.51 0.52 0.431644.60.39 0.08 0.121662.30.33 0.07 0.121688.20.91 0.19 0.181723.30.25 0.05 0.121739.10.33 0.07 0.121755.30.48 0.10 0.151767.60.21 0.04 0.091772.80.70 0.15 0.181785.10.37 0.08 0.151795 90.27 0.06 0.091840.70.15 0.03 0.091851.31.35 0.28 0.251863 90.21 0.04 0.091866.80.52 0.11 0.181893.80.81 0.17 0.251903.30.62 0.13 0.121991.80.21 0.04 0.091999.40.21 0.04 0.092060.30.54 0.11 0.182068.50.23 0.05 0.122100.90.35 0.07 0.122107.00.77 0.16 0.182116.50.60 0.12 0.212141.80.39 0.08 0.152171.30.15 0.03 0.092232.10.21 0.04 0.092235.20.21 0.04 0.092245.90.23 0.05 0.092272.90.21 0.04 0.092289.20.23 0.05 0.122308.20.25 0.05 0.122318.20.64 0.13 0.152323.70.29 0.06 0.122336.90.48 0.10 0.152362.20.23 0.05 0.122403.20.31 0.06 0.122422.80.54 0.11 0.182510.10.12 0.03 0.092576.40.23 0.05 0.122584.10.73 0.15 0.152600.00.21 0.04 0.092607.70.31 0.06 0.122660.60.23 0.05 0.09完整細(xì)胞MALDIMRSA 01/270030Data:a0001.1 3 Jul 97 17:50 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2688.00.21 0.04 0.092713.10.25 0.05 0.122970.70.62 0.13 0.153054.80.77 0.16 0.153221.10.50 0.10 0.153289.10.12 0.03 0.093440.50.44 0.09 0.153449.40.15 0.03 0.093512.50.39 0.08 0.125025.40.21 0.04 0.09完整細(xì)胞MALDIMRSA 02/270238Data:a0002.3 3 Jul 97 17:53 Ca1:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志617.7 1.34 0.36 0.12659.0 0.78 0.21 0.09669.0 0.33 0.09 0.09675.1 52.34 13.94 1.56687.7 1.45 0.39 0.12691.2 100.00 26.63 2.70695.9 1.23 0.33 0.12707.2 92.97 24.75 2.05713.2 2.12 0.56 0.15715.8 0.67 0.18 0.09724.7 36.05 9.60 0.77808.6 0.67 0.18 0.09881.0 0.67 0.18 0.09899.0 7.92 2.11 0.28902.4 15.62 4.16 0.52907.6 0.67 0.18 0.09913.3 3.12 0.83 0.15919.3 16.41 4.37 0.52937.1 14.29 3.80 0.40952.0 4.58 1.22 0.181131.07.25 1.93 0.311133.80.78 0.21 0.091147.63.91 1.04 0.211322.61.34 0.36 0.121328.50.78 0.21 0.121344.72.12 0.56 0.151358.63.12 0.83 0.151388.41.23 0.33 0.121405.90.67 0.18 0.091730.81.12 0.30 0.09完整細(xì)胞MALDI艱難梭菌NCTC 11204Data:diff0032.12 18 Jun97 15:11 Cal:test 25 Apr 97 11:31Kratos Kompact MALDI 2 V5.2.1:-Linear High Power:90,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志529.015.84 3.89 44.21 U541.93.93 0.97 12.10 U545.20.31 0.08 1.72 U546.80.45 0.11 2.11 U550.50.48 0.12 1.81 U568.91.46 0.36 4.38585.20.95 0.23 2.63 U597.71.34 0.33 3.89 U613.71.60 0.39 2.63629.520.23 4.97 30.58643.45.83 1.43 10.69655.99.17 2.25 14.54 U661.50.34 0.08 1.50 U673.5100.00 24.59 152.33695.717.37 4.27 39.74712.14.01 0.99 9.22738.00.83 0.20 1.75766.80.86 0.21 2.30787.752.84 12.99 88.63 U811.51.88 0.46 3.80826.40.90 0.22 1.87838.71.04 0.26 2.45853.010.98 2.70 20.68867.73.31 0.81 6.74 U881.13.17 0.78 7.78897.591.96 22.61 127.14 U920.929.54 7.26 61.03937.37.40 1.82 16.76 U942.50.90 0.22 2.18 U962.11.36 0.33 2.081013.20.82 0.20 1.56 U1077.11.98 0.49 3.621091.41.19 0.29 2.111106.51.04 0.26 1.961122.98.76 2.15 15.23 U1243.60.39 0.10 1.591347.11.57 0.39 2.88 U1403.60.72 0.18 2.02 U完整細(xì)胞MALDI艱難梭菌NCTC 11206Data:diff0033.13 18 Jun 97 15:12 Cal:test 25 Apr 97 11:31Kratos Kompact MALDI 2 V5.2.1:-Linear High Power:90.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志529.08.35 2.35 20.50541.95.82 1.64 17.19553.21.57 0.44 2.73 U569.11.89 0.53 6.16585.21.19 0.33 2.57 U597.41.09 0.31 3.00 U611.40.43 0.12 1.78 U613.30.78 0.22 1.65 U629.325.04 7.05 33.18 U643.46.81 1.92 9.83655.710.08 2.84 17.80673.2100.00 28.18 138.30 U695.523.15 6.52 49.20711.80.79 0.22 2.05787.733.01 9.30 55.09803.48.09 2.28 16.12 U853.08.47 2.39 14.49866.81.76 0.50 3.68880.52.42 0.68 5.33896.974.00 20.85 97.27920 630.05 8.47 56.77937.00.71 0.20 1.87 U1077.4 1.61 0.45 2.971122.3 6.79 1.91 11.641347.8 0.99 0.28 2.21完整細(xì)胞MALDI艱難梭菌PERFData:diff0037.17 18 Jun 97 15:19 Cal:test 25 Apr 97 11:31Kratos Kompact MALDI 2 V5.2.1:-Linear High Power:95,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志529.29.64 2.52 15.32551.41.10 0.32 1.19 U569.31.93 0.56 3.68585.71.68 0.49 1.93598.11.15 0.34 1.41611.90.61 0.18 1.26 U613.50.47 0.14 1.23 U627.96.35 1.86 14.15 U629.811.47 3.35 17.13 U643.95.2 3 1.53 6.10655.96.53 1.91 7.54674.092.77 27.10 99.30696.014.97 4.37 22.15712.10.84 0.25 1.01735.70.47 0.14 0.98 U738.30.56 0.16 1.07 U788.216.91 4.94 20.77810.90.84 0.25 1.13838.40.97 0.28 1.35853.212.49 3.65 14.71867.13.01 0.88 4.29881.13.79 1.11 4.99897.5100.00 29.22 97.15921.126.23 7.66 37.68937.31.58 0.46 2.14 U961.22.24 0.65 2.701078.4 3.40 0.99 3.981091.4 1.00 0.29 1.381105.5 1.25 0.36 1.561122.6 11.95 3.49 13.051347.4 1.87 0.55 3.12 U完整細(xì)胞MALDI艱難梭菌TETANIData:diff0039.19 18 Jun 97 15:22 Cal:test 25 Apr 97 11:31Kratos Kompact MALDI 2 V5.2.1:-Linear High Power:95.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志513.2 1.37 0.38 3.71 U529.2 7.66 2.10 19.88 U542.1 0.34 0.09 1.41 U547.4 0.48 0.13 1.44 U551.4 1.53 0.42 1.75 U569.3 2.19 0.60 5.58 U585.5 2.06 0.56 3.80 U597.9 2.21 0.61 3.74629.5 24.24 6.65 32.02643.9 5.57 1.53 9.50656.2 9.64 2.65 14.83673.7 100.00 27.44 141.70696.0 24.28 6.66 48.71712.1 1.62 0.44 3.83738.6 0.94 0.26 1.75788.2 23.37 6.41 39.19853.2 13.08 3.59 22.86867.7 2.99 0.82 5.91881.4 3.71 1.02 6.86897.7 84.60 23.21 115.41921.1 32.93 9.04 61.70937.9 1.96 0.54 4.44 U943.7 0.69 0.19 1.84 U1077.73.22 0.88 6.281092.70.63 0.17 1.471106.20.84 0.23 1.781123.210.41 2.86 17.651303.70.63 0.17 1.691348.51.25 0.34 2.30完整細(xì)胞MALDIMyco Cardiff 1/0036cData:CAR0002.2 30 May 97 17:06 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75.tDE @ 3819(bin 109)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志792.60.800.05 0.31838.00.920.06 0.34850.11.780.11 0.67 U863.124.18 1.44 6.00 U877.64.430.26 1.38 U883.86.540.39 1.69 U896.54.010.24 1.16904.43.320.20 1.32 U912.412.09 0.72 3.16 U922.74.800.29 1.26 U938.92.230.13 0.43 U950.221.29 1.27 4.50 U964.63.030.18 0.80 U978.445.32 2.71 11.46 U993.09.200.55 2.51 U1006.4 100.00 5.97 24.97 U1020.9 5.730.34 1.90 U1034.8 36.44 2.18 11.46 U1040.0 34.03 2.03 10.75 U1051.0 8.3 6 0.50 1.84 U1067.6 58.51 3.49 13.20 U1080.0 8.210.49 1.93 U1094.7 29.85 1.78 7.44 U1108.5 8.800.53 2.18 U1122.1 12.20 0.73 3.46 U1136.4 13.15 0.79 2.45 U1149.8 5.720.34 1.75 U1166.6 10.02 0.60 2.11 U1180.2 4.500.27 1.16 U1195.2 7.040.42 1.16 U1205.0 4.060.24 0.89 U1218.5 6.060.36 1.59 U1231.7 7.100.42 1.59 U1245.7 8.620.51 2.27 U1259.8 13.71 0.82 2.91 U1277.3 12.19 0.73 2.82 U1288.5 10.42 0.62 2.54 U1304.1 34.21 2.04 5.94 U1318.5 13.90 0.83 3.65 U1332.6 13.05 0.78 2.91 U1346.5 18.15 1.08 5.02 U1361.1 15.28 0.91 3.80 U1373.7 7.520.45 1.96 U1388.4 10.30 0.62 2.21 U1404.7 3.750.22 1.38 U1416.8 6.920.41 1.84 U1425.3 3.950.24 1.38 U1432.5 4.510.27 1.10 U1445.8 8.300.50 1.53 U1458.0 4.880.29 1.16 U1475.8 15.08 0.90 3.52 U1493.6 16.57 0.99 1.87 U1532.3 20.83 1.24 1.50 U1555.7 5.540.33 1.38 U1573.2 17.27 1.03 3.40 U1591.3 14.10 0.84 3.74 U1598.1 19.52 1.17 2.70 U完整細(xì)胞MALDIMyco Cardiff 1/0036cData:CAR0002.2 30 May 97 17:06 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 3819(bin 109)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志1626.24.310.26 1.44 U1646.516.75 1.00 2.54 U1671.98.900.53 1.62 U1681.620.03 1.20 3.49 U1703.815.34 0.92 3.40 U1715.91.370.08 0.74 U1732.011.64 0.70 2.76 U1741.112.82 0.77 3.03 U1755.316.73 1.00 5.09 U1760.913.23 0.79 3.71 U1773.22.200.13 0.83 U1787.15.270.32 1.26 U1802.05.910.35 1.47 U1817.798.66 5.89 18.72 U1839.910.54 0.63 2.57 U1866.87.460.45 1.19 U1880.32.030.12 0.59 U1889.710.39 0.62 2.70 U1907.53.850.23 1.19 U1917.07.300.44 1.72 U1929.06.410.38 1.78 U1935.23.230.19 1.10 U1949.85.920.35 1.19 U1963.25.030.30 1.26 U1973.730.14 1.80 5.06 U1988.923.53 1.41 5.33 U2004.118.22 1.09 3.92 U2018.918.35 1.10 3.48 U2031.33.020.18 1.23 U2044.56.760.40 1.78 U2063.85.010.30 0.92 U2080.17.170.43 1.65 U2091.46.060.36 1.29 U2104.82.850.17 1.16 U2110.94.510.27 1.50 U2120.97.320.44 1.87 U2133.17.950.47 1.72 U2153.77.880.47 2.18 U2160.36.640.40 1.65 U2171.33.650.22 1.23 U2182.74.340.26 1.19 U2201.311.27 0.67 2.24 U2214.211.61 0.69 2.02 U2234.811.92 0.71 2.94 U2254.519.55 1.17 4.60 U2271.615.04 0.90 3.46 U2286.94.880.29 1.32 U2305.026.39 1.58 6.65 U2319.114.10 0.84 2.82 U2336.54.340.26 1.35 U2350.73.330.20 0.89 U2369.110.27 0.61 1.50 U2417.69.350.56 1.19 U2433.014.51 0.87 3.00 U2443.86.350.38 1.47 U2461.122.88 1.37 4.53 U2488.82.820.17 0.67 U完整細(xì)胞MALDIMyco Cardiff 1/0036cData:CAR0002.2 30 May 97 17:06 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 3819(bin 109)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志2507.37.93 0.47 1.59 U2522.08.49 0.51 1.84 U2539.111.36 0.68 1.56 U2579.87.17 0.43 1.29 U2604.89.66 0.58 1.53 U2620.85.57 0.33 1.19 U2644.12.89 0.17 0.98 U2657.211.59 0.69 2.02 U2676.37.07 0.42 1.01 U2710.625.00 1.49 3.86 U2724.44.58 0.27 1.50 U2769.09.57 0.57 1.72 U2789.54.88 0.29 1.04 U2805.015.85 0.95 2.76 U2864.410.04 0.60 1.472900.52.35 0.14 0.492948.515.82 0.95 2.302999.18.21 0.49 1.233064.24.49 0.27 0.403111.02.87 0.17 0.613147.54.00 0.24 0.61 U3177.33.42 0.20 0.55 U3207.72.22 0.13 0.583224.33.25 0.19 0.523250.70.98 0.06 0.253340.34.66 0.28 0.463378.10.74 0.04 0.287634.529.92 1.79 2.14完整細(xì)胞MALDIMyco Cardiff 31/0352cData:CAR0082.2 3 Jun 97 16:27 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志881.3 1.06 0.11 0.55913.0 2.46 0.25 1.691006.13.11 0.31 1.991035.41.25 0.13 0.641065.52.28 0.23 0.58 U1072.03.14 0.32 1.47 U1087.22.48 0.25 1.23 U1103.81.87 0.19 0.671137.72.11 0.21 0.52 U1167.22.35 0.24 1.011233.72.86 0.29 1.72 U1254.72.31 0.23 1.44 U1260.85.44 0.55 3.09 U1268.51.85 0.19 1.41 U1276.611.66 1.17 6.62 U1290.55.08 0.51 2.73 U1303.157.08 5.73 27.42 U1318.927.75 2.79 16.79 U1330.930.54 3.07 17.92 U1345.840.66 4.08 23.901361.418.86 1.89 10.51 U1373.317.10 1.72 10.42 U1389.16.43 0.65 4.201401.91.58 0.16 1.071418.61.93 0.19 1.01 U1426.43.03 0.30 1.16 U1449.01.75 0.18 0.95 U1479.43.75 0.38 0.74 U1488.13.24 0.33 1.38 U1496.62.00 0.20 1.41 U1507.52.48 0.25 1.04 U1514.21.44 0.14 0.89 U1539.74.71 0.47 1.10 U1552.34.02 0.40 0.98 U1573.22.03 0.20 0.70 U1606.44.72 0.47 0.89 U1621.62.86 0.29 0.95 U1637.71.11 0.11 0.86 U1642.61.73 0.17 1.07 U1658.42.01 0.20 1.04 U1665.01.79 0.18 0.98 U1677.72.37 0.24 1.13 U1696.05.18 0.52 1.38 U1714.71.05 0.11 0.92 U1722.63.32 0.33 2.02 U1739.53.88 0.39 1.53 U1749.42.18 0.22 1.23 U1756.51.56 0.16 1.16 U1765.63.86 0.39 1.26 U1781.12.44 0.25 1.50 U1790.71.62 0.16 1.01 U1809.64.88 0.49 1.87 U1829.43.17 0.32 1.07 U1842.30.91 0.09 0.64 U1854.50.61 0.06 0.64 U1867.63.09 0.31 1.01 U1886.90.62 0.06 0.52 U完整細(xì)胞MALDIMyco Cardiff 31/0352cData:CAR0082.2 3 Jun 97 16:27 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志1895.91.31 0.13 0.92 U1902.91.12 0.11 0.86 U1926.11.62 0.16 1.44 U1931.52.54 0.25 2.05 U1947.317.04 1.71 8.64 U1961.97.84 0.79 4.93 U1974.1100.00 10.04 52.36 U1989.759.98 6.02 32.94 U2002.046.84 4.70 26.07 U2017.262.90 6.32 35.97 U2032.120.67 2.08 13.27 U2044.516.82 1.69 10.94 U2059.97.32 0.74 5.332073.21.73 0.17 1.532088.31.39 0.14 1.042109.12.66 0.27 0.98 U2121.33.56 0.36 1.59 U2152.85.18 0.52 1.62 U2164.26.95 0.70 2.70 U2175.74.13 0.42 1.87 U2192.01.62 0.16 1.19 U2216.94.62 0.46 1.29 U2234.31.47 0.15 0.80 U2243.32.61 0.26 1.62 U2252.24.99 0.50 1.96 U2266.61.88 0.19 1.10 U2278.32.03 0.20 1.29 U2291.01.43 0.14 0.89 U2299.61.43 0.14 1.01 U2307.33.22 0.32 1.19 U2325.11.07 0.11 0.83 U2339.72.68 0.27 1.19 U2354.43.79 0.38 1.38 U2370.05.91 0.59 2.70 U2388.94.53 0.45 1.41 U2416.72.13 0.21 0.86 U2432.16.65 0.67 1.69 U2464.42.95 0.30 1.23 U2479.46.16 0.62 1.72 U2504.04.20 0.42 1.75 U2527.22.68 0.27 1.47 U2538.25.39 0.54 1.53 U2568.34.26 0.43 1.41 U2592.84.20 0.42 1.41 U2618.82.39 0.24 1.10 U2633.92.35 0.24 1.47 U2661.17.83 0.79 2.48 U2704.766.01 6.63 24.20 U2751.21.94 0.20 1.10 U2762.65.71 0.57 1.44 U2795.51.72 0.17 0.80 U2815.02.04 0.20 1.04 U2825.62.13 0.21 1.29 U2849.35.40 0.54 1.62 U2869.53.28 0.33 1.04 U2894.91.56 0.16 0.80 U2919.92.12 0.21 0.83 U完整細(xì)胞MALDIMyco Cardiff 31/0352cData:CAR0082.2 3 Jun 97 16:27 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2928.61.05 0.11 0.86 U2943.44.14 0.42 1.65 U2967.13.05 0.31 1.23 U2981.51.00 0.10 0.64 U2995.01.86 0.19 0.89 U3018.32.83 0.28 1.35 U3032.90.86 0.09 0.64 U3054.84.50 0.45 0.92 U3092.02.53 0.25 0.86 U3108.93.68 0.37 1.78 U3125.21.38 0.14 0.61 U3148.54.60 0.46 1.65 U3167.71.62 0.16 0.67 U3200.82.17 0.22 0.61 U3237.24.58 0.46 1.26 U3276.62.28 0.23 0.95 U3332.13.02 0.30 1.07 U3362.75.16 0.52 0.98 U3422.216.59 1.67 5.88 U3449.41.63 0.16 0.52 U3490.13.20 0.32 0.743591.41.83 0.18 0.52 U3642.03.64 0.37 0.83 U3709.73.62 0.36 0.58 U3772.72.57 0.26 0.643811.72.13 0.21 0.58 U3871.51.39 0.14 0.52 U3896.93.04 0.31 1.35 U3914.02.60 0.26 1.07 U3933.02.07 0.21 0.83 U3974.61.33 0.13 0.58 U3987.11.75 0.18 0.61 U4859.83.58 0.36 0.77完整細(xì)胞MALDIMyco Cardiff 33/0589cData:CAR0086.6 3 Jun 97 16:37 Cal:test 25 Apr-97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志526.80.54 0.04 0.43866.21.89 0.15 1.23882.13.62 0.28 1.81898.52.14 0.17 0.89915.31.18 0.09 0.49940.61.98 0.15 0.89956.11.12 0.09 0.43982.31.35 0.11 0.521008.5 3.87 0.30 0.581020.0 1.59 0.12 0.431056.2 2.95 0.23 0.95 U1072.0 7.08 0.55 2.21 U1088.1 3.06 0.24 1.50 U1094.7 2.11 0.16 0.92 U1104.7 0.92 0.07 0.58 U1111.7 0.88 0.07 0.49 U1122.7 1.80 0.14 0.58 U1136.7 1.69 0.13 0.61 U1153.0 1.45 0.11 0.461166.2 2.77 0.22 0.861193.5 2.50 0.20 0.551212.9 2.98 0.23 0.741228.4 1.70 0.13 1.04 U1233.7 3.06 0.24 1.29 U1255.1 6.02 0.47 1.75 U1261.4 7.57 0.59 3.71 U1268.5 3.15 0.25 1.56 U1277.3 15.32 1.20 4.78 U1290.2 9.59 0.75 3.86 U1295.9 6.04 0.47 3.37 U1304.1 36.71 2.87 14.31 U1319.9 16.58 1.30 6.83 U1331.6 18.41 1.44 7.66 U1347.5 8.59 0.67 3.65 U1360.0 5.72 0.45 2.14 U1375.8 3.06 0.24 1.10 U1390.2 1.99 0.16 0.58 U1401.2 1.43 0.11 0.58 U1418.9 2.09 0.16 0.89 U1426.8 1.15 0.09 0.55 U1442.2 4.20 0.33 1.01 U1451.5 2.85 0.22 0.92 U1466.3 4.94 0.39 1.69 U1477.6 3.23 0.25 1.29 U1487.4 6.21 0.49 1.26 U1506.1 2.02 0.16 0.98 U1511.2 1.44 0.11 0.92 U1522.3 3.24 0.25 1.01 U1535.2 3.73 0.29 1.47 U1554.5 7.65 0.60 2.27 U1570.2 7.55 0.59 1.81 U1582.3 4.24 0.33 1.75 U1597.0 3.59 0.28 1.16 U1612.1 4.07 0.32 1.19 U1625.1 3.76 0.29 1.72 U1637.7 2.89 0.23 1.101653.4 3.32 0.26 1.87完整細(xì)胞MALDIMyco Cardiff 33/0589cData:CAR0086.6 3 Jun 97 16:37 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1667.35.64 0.44 2.701680.814.52 1.14 6.801696.015.33 1.20 6.281714.736.25 2.84 14.86 U1729.298.68 7.72 34.93 U1744.257.05 4.46 23.65 U1757.361.17 4.78 26.87 U1771.6100.00 7.82 42.74 U1786.380.92 6.33 34.87 U1800.050.42 3.94 23.19 U1814.436.86 2.88 16.64 U1828.230.88 2.42 14.43 U1842.710.60 0.83 5.271857.02.74 0.21 1.411871.72.22 0.17 1.261887.72.16 0.17 0.74 U1904.63.73 0.29 1.16 U1914.94.05 0.32 1.38 U1924.02.46 0.19 0.95 U1941.15.97 0.47 1.32 U1961.15.53 0.43 1.87 U1975.06.85 0.54 2.18 U1989.711.09 0.87 3.40 U2001.56.43 0.50 2.27 U2018.95.65 0.44 2.11 U2032.16.17 0.48 1.50 U2062.13.43 0.27 0.98 U2073.73.62 0.28 1.19 U2088.31.63 0.13 0.89 U2096.61.64 0.13 0.86 U2108.34.11 0.32 1.32 U2119.17.04 0.55 2.73 U2133.17.93 0.62 2.48 U2163.88.24 0.64 1.75 U2174.85.87 0.46 1.35 U2194.70.77 0.06 0.58 U2204.93.96 0.31 0.95 U2223.62.81 0.22 0.83 U2234.81.96 0.15 0.89 U2245.54.07 0.32 1.07 U2259.03.26 0.25 1.44 U2269.81.26 0.10 0.77 U2285.13.20 0.25 0.95 U2291.41.24 0.10 0.80 U2299.62.10 0.16 1.10 U2306.92.32 0.18 1.38 U2313.72.44 0.19 0.95 U2328.32.38 0.19 0.89 U2342.44.14 0.32 1.19 U2361.23.87 0.30 1.59 U2371.89.83 0.77 2.88 U2388.93.20 0.25 1.13 U2399.51.40 0.11 0.83 U2419.03.38 0.26 0.80 U2433.92.72 0.21 1.10 U2461.65.96 0.47 1.19 U2479.43.27 0.26 1.29 U完整細(xì)胞MALDIMyco Cardiff 33/0589cData:CAR0086.6 3 Jun 97 16:37 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2492.22.89 0.23 0.98 U2506.86.39 0.50 1.81 U2520.12.61 0.20 1.10 U2538.65.71 0.45 1.59 U2550.66.99 0.55 2.11 U2565.96.46 0.50 1.90 U2577.94.69 0.37 2.02 U2593.76.97 0.55 1.96 U2607.73.61 0.28 1.44 U2619.84.81 0.38 1.26 U2651.93.87 0.30 0.89 U2664.52.67 0.21 1.16 U2689.03.03 0.24 0.77 U2706.215.50 1.21 5.67 U2719.57.12 0.56 2.02 U2743.73.91 0.31 1.23 U2768.59.32 0.73 1.32 U2818.05.71 0.45 1.50 U2838.22.36 0.18 0.64 U2855.83.89 0.30 0.98 U2875.13.68 0.29 0.95 U2904.04.13 0.32 0.922932.65.51 0.43 1.41 U2964.06.64 0.52 1.69 U2982.55.51 0.43 1.53 U3002.29.77 0.76 2.18 U3016.23.11 0.24 1.41 U3031.87.93 0.62 2.45 U3048.05.71 0.45 1.96 U3060.03.94 0.31 1.78 U3074.73.00 0.23 1.29 U3088.33.96 0.31 1.65 U3103.12.11 0.17 1.07 U3149.64.22 0.33 0.743193.32.36 0.18 0.67 U3239.94.80 0.38 0.89 U3261.52.81 0.22 0.52 U3311.45.77 0.45 0.74 U3389.73.50 0.27 0.58 U3400.11.91 0.15 0.74 U3424.56.95 0.54 1.56 U3455.51.48 0.12 0.64 U3475.63.00 0.23 0.89 U3501.85.20 0.41 0.80 U3527.61.54 0.12 0.58 U3552.93.18 0.25 0.433700.52.65 0.21 0.553766.31.61 0.13 0.403801.21.10 0.09 0.493875.13.12 0.24 1.07 U3897.53.43 0.27 0.89 U3918.23.48 0.27 0.77 U完整細(xì)胞MALDIMyco Cardiff 63/0545cData:CAR0146.6 4 Jun 97 14:12 Ca1:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志646.7 4.03 0.37 3.43654.6 0.85 0.08 0.86670.5 3.25 0.30 2.45686.7 1.40 0.13 0.67710.5 1.37 0.12 0.37733.6 3.15 0.29 1.50751.4 1.30 0.12 0.55776.5 4.83 0.44 2.79792.9 3.97 0.36 2.24810.3 3.97 0.36 2.11 U817.3 1.38 0.13 0.77 U826.8 1.15 0.10 0.55 U836.4 2.39 0.22 1.41 U844.0 0.41 0.04 0.40852.6 2.16 0.20 1.16 U860.3 3.65 0.33 2.79 U866.2 5.41 0.49 3.19 U875.9 3.68 0.34 2.11 U882.1 12.29 1.12 6.16 U898.2 13.01 1.19 5.73 U915.0 9.23 0.84 2.94932.2 1.49 0.14 0.92 U940.6 5.60 0.51 2.21 U956.9 4.35 0.40 2.18973.1 4.40 0.40 1.26 U990.0 2.90 0.26 0.95 U1001.65.33 0.49 1.35 U1018.82.88 0.26 1.50 U1026.01.58 0.14 0.77 U1034.81.89 0.17 0.83 U1044.92.08 0.19 0.89 U1057.82.26 0.21 1.07 U1072.315.17 1.38 5.27 U1088.415.21 1.39 5.82 U1104.48.50 0.78 3.03 U1128.76.32 0.58 1.59 U1142.50.98 0.09 0.64 U1146.92.69 0.25 0.98 U1165.61.38 0.13 0.98 U1170.41.94 0.18 1.04 U1184.42.37 0.22 1.07 U1191.61.27 0.12 0.74 U1199.10.66 0.06 0.58 U1206.61.40 0.13 0.86 U1215.52.61 0.24 1.07 U1228.71.76 0.16 1.16 U1234.42.55 0.23 1.50 U1249.71.84 0.17 1.38 U1254.73.64 0.33 2.24 U1261.89.57 0.87 5.06 U1268.81.17 0.11 1.29 U1277.319.25 1.76 8.43 U1290.522.02 2.01 7.11 U1304.552.42 4.79 24.05 U1319.936.04 3.29 17.03 U1332.324.24 2.21 12.16 U1347.916.71 1.52 8.98 U完整細(xì)胞MALDIMyco Cardiff 63/0545cData:CAR0146.6 4 Jun 97 14:12 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1360.45.95 0.54 2.79 U1376.56.73 0.61 2.30 U1406.82.65 0.24 0.98 U1426.14.18 0.38 1.07 U1435.42.06 0.19 1.16 U1442.91.28 0.12 0.95 U1451.53.78 0.34 1.84 U1461.33.90 0.36 1.44 U1477.65.59 0.51 1.38 U1489.61.65 0.15 1.07 U1496.92.68 0.24 1.62 U1507.55.24 0.48 1.47 U1525.29.16 0.84 1.87 U1559.33.47 0.32 1.10 U1572.96.28 0.57 1.90 U1587.94.13 0.38 1.35 U1598.12.75 0.25 1.04 U1612.15.71 0.52 2.24 U1625.82.27 0.21 1.41 U1640.02.08 0.19 0.77 U1653.83.96 0.36 2.08 U1667.73.65 0.33 2.451681.611.57 1.06 6.221696.415.52 1.42 6.991714.724.69 2.25 12.41 U1729.2100.00 9.13 39.61 U1744.668.43 6.25 30.85 U1757.738.83 3.55 19.85 U1772.077.34 7.06 38.02 U1786.765.16 5.95 32.41 U1800.431.38 2.86 17.10 U1814.821.67 1.98 12.011829.418.39 1.68 9.991843.27.08 1.65 4.531857.80.80 0.07 0.49 U1871.31.55 0.14 1.13 U1888.13.46 0.32 1.07 U1900.02.64 0.24 1.26 U1907.91.46 0.13 1.04 U1917.41.22 0.11 0.83 U1924.42.07 0.19 0.98 U1936.51.74 0.16 0.98 U1945.22.36 0.22 1.23 U1954.01.41 0.13 0.67 U1965.72.19 0.20 1.19 U1986.76.56 0.60 1.41 U2004.52.59 0.24 1.29 U2018.53.81 0.35 1.01 U2041.92.02 0.18 0.67 U2057.32.84 0.26 1.23 U2080.64.89 0.45 1.13 U2101.33.51 0.32 0.80 U2118.71.93 0.18 0.70 U2141.85.03 0.46 0.89 U2166.94.49 0.41 1.13 U2186.31.41 0.13 0.55 U2204.02.51 0.23 0.98 U完整細(xì)胞MALDIMyco Cardiff 63/0545cData:CAR0146.6 4 Jun 97 14:12 Cal:test 25 Apr 97 11:25Kratos Kompact MULDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志2218.23.01 0.27 1.10 U2231.61.93 0.18 0.77 U2253.12.55 0.23 0.80 U2273.42.08 0.19 0.89 U2287.40.95 0.09 0.55 U2299.63.37 0.31 0.92 U2332.83.52 0.32 0.70 U2347.91.63 0.15 0.86 U2370.03.27 0.30 0.86 U2391.21.02 0.09 0.55 U2419.02.63 0.24 0.70 U2432.52.47 0.23 0.74 U2455.92.65 0.24 0.55 U2486.02.48 0.23 0.74 U2495.51.56 0.14 0.67 U2520.61.64 0.15 0.46 U2537.22.22 0.20 0.67 U2576.42.61 0.24 0.61 U2591.30.79 0.07 0.43 U2606.81.79 0.16 0.64 U2637.34.91 0.45 0.46 U2707.25.29 0.48 1.84 U2723.02.86 0.26 0.89 U2758.62.45 0.22 0.462816.02.41 0.22 0.70 U2836.12.00 0.18 0.58 U2876.11.80 0.16 0.55 U2916.82.17 0.20 0.55 U2948.52.41 0.22 0.64 U2966.61.26 0.12 0.40 U2999.13.35 0.31 0.493056.91.77 0.16 0.433131.64.02 0.37 0.40 U3177.81.35 0.12 0.37 U3266.93.34 0.30 0.553424.53.43 0.31 0.463525.91.33 0.12 0.403663.71.51 0.14 0.373849.80.90 0.08 0.433915.21.64 0.15 0.40完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Ktatos Kompact MALDI 2 V5.2.1:+Linear High Power:60.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志502.1 0.22 0.03 0.09507.9 0.34 0.04 0.12518.8 0.43 0.06 0.12524.8 26.09 3.36 2.30542.7 100.00 12.86 9.07 U552.9 13.82 1.78 0.80 U565.0 14.18 1.82 1.23580.9 10.34 1.33 0.67587.3 2.92 0.38 0.31604.1 4.12 0.53 0.34619.1 0.74 0.09 0.12635.7 0.65 0.08 0.12653.2 1.38 0.18 0.18657.3 8.98 1.16 0.77665.6 14.43 1.86 1.38673.4 15.91 2.05 1.26688.2 10.09 1.30 0.80699.9 0.71 0.09 0.12701.7 0.22 0.03 0.09713.7 52.09 6.70 4.14729.2 16.86 2.17 1.07 U735.1 27.35 3.52 2.11 U740.3 5.78 0.74 0.49 U750.3 36.86 4.74 1.16771.7 0.58 0.08 0.15783.1 10.80 1.39 0.37810.3 0.18 0.02 0.09820.8 0.34 0.04 0.12896.8 0.18 0.02 0.091016.30.77 0.10 0.181177.20.46 0.06 0.121366.00.22 0.03 0.091603.00.34 0.04 0.091876.60.49 0.06 0.121942.73.66 0.47 0.461964.58.65 1.11 1.231980.41.08 0.14 0.211987.21.26 0.16 0.212009.60.83 0.11 0.152074.17.42 0.95 0.862096.113.78 1.77 1.532112.24.74 0.61 0.612118.30.86 0.11 0.152128.70.46 0.06 0.092134.41.23 0.16 0.152176.60.37 0.05 0.122213.81.82 0.23 0.252258.50.52 0.07 0.122313.70.31 0.04 0.092321.40.80 0.10 0.122349.30.46 0.06 0.122372.70.83 0.11 0.182388.00.58 0.08 0.122442.80.95 0.12 0.152446.61.11 0.14 0.182470.00.68 0.09 0.152476.11.72 0.22 0.18完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2504.40.52 0.07 0.122522.50.22 0.03 0.092533.40.46 0.06 0.122543.42.80 0.36 0.182552.50.77 0.10 0.122564.92.00 0.26 0.182575.00.95 0.12 0.122585.60.58 0.08 0.122593.31.14 0.15 0.122601.41.91 0.25 0.182627.10.89 0.11 0.122639.77.75 1.00 0.522652.80.31 0.04 0.092660.10.58 0.08 0.122678 72.43 0.31 0.182685.64.00 0.51 0.282696.40.77 0.10 0.122702.33.32 0.43 0.212720.00.68 0.09 0.122740.80.18 0.02 0.092746.70.71 0.09 0.122757.61.29 0.17 0.182771.52.52 0.32 0.212779.50.18 0.02 0.092784.50.31 0.04 0.092790.00.86 0.11 0.122794.51.14 0.15 0.122808.02.28 0.29 0.212829.10.83 0.11 0.152833.61.20 0.15 0.182848.73.63 0.47 0.282858.910.80 1.39 0.372900.55.42 0.70 0.252918.83.66 0.47 0.312928.61.14 0.15 0.152942.91.23 0.16 0.182951.11.17 0.15 0.152958.80.77 0.10 0.122962.90.31 0.04 0.092972.72.28 0.29 0.152984.61.88 0.24 0.252999.60.74 0.09 0.123005.80.31 0.04 0.093011.50.74 0.09 0.153019.31.45 0.19 0.123033.90.58 0.08 0.123037.50.98 0.13 0.153047.51.42 0.18 0.183072.62.74 0.35 0.183087.81.08 0.14 0.093096.20.83 0.11 0.123101.50.46 0.06 0.123109.90.31 0.04 0.093115.20.34 0.04 0.093120.51.11 0.14 0.183142.25.14 0.66 0.213146.90.22 0.03 0.09完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志3152.20.31 0.04 0.093162.31.02 0.13 0.153169.30.74 0.09 0.123182.61.69 0.22 0.153193.81.72 0.22 0.123201.80.34 0.04 0.123209.32.98 0.38 0.153230.30.58 0.08 0.123250.21.94 0.25 0.183279.95.17 0.66 0.253291.30.65 0.08 0.093311.40.18 0.02 0.093317.90.46 0.06 0.123325.60.40 0.05 0.093332.61.02 0.13 0.153340.30.58 0.08 0.123346.90.62 0.08 0.123356.21.91 0.25 0.183382.04.68 0.60 0.343400.12.49 0.32 0.183412.81.02 0.13 0.153418.40.43 0.06 0.093423.31.14 0.15 0.093439.40.83 0.11 0.153465.00.34 0.04 0.093474.45.48 0.70 0.253491.25.78 0.74 0.283511.33.94 0.51 0.213523.11.38 0.18 0.183534.47.08 0.91 0.373551.22.77 0.36 0.183563.71.97 0.25 0.183571.63.45 0.44 0.253596.50.18 0.02 0.093605.00.62 0.08 0.123615.80.92 0.12 0.153626.60.74 0.09 0.123631.71.02 0.13 0.123641.40.65 0.08 0.093650.00.65 0.08 0.123672.95.78 0.74 0.313686.72.06 0.27 0.283699.30.74 0.09 0.153710.21.85 0.24 0.253733.31.05 0.13 0.153743.71.94 0.25 0.253762.30.58 0.08 0.123769.81.32 0.17 0.153780.32.03 0.26 0.213798.92.68 0.34 0.153836.31.94 0.25 0.213843.90.58 0.08 0.123858.61.17 0.15 0.183867.41.82 0.23 0.183896.91.35 0.17 0.153922.32.31 0.30 0.153935.40.77 0.10 0.12完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志3941.31.11 0.14 0.153950.80.83 0.11 0.153956.11.75 0.23 0.154010.55.45 0.70 0.374023.73.75 0.48 0.184050.72.71 0.35 0.254071.23.11 0.40 0.154093.63.45 0.44 0.254106.30.92 0.12 0.154119.63.35 0.43 0.254153.12.09 0.27 0.124166.51.69 0.22 0.184181.85.57 0.72 0.254205.71.23 0.16 0.184220.40.43 0.06 0.094246.92.80 0.36 0.124258.01.54 0.20 0.214300.01.75 0.23 0.154314.90.55 0.07 0.094324.92.09 0.27 0.154352.30.83 0.11 0.154371.01.35 0.17 0.154386.00.89 0.11 0.124435.70.98 0.13 0.124468.50.80 0.10 0.124510.91.32 0.17 0.184564.50.55 0.07 0.094573.40.31 0.04 0.094606.71.54 0.20 0.154630.51.02 0.13 0.154647.90.31 0.04 0.094695.77.82 1.01 0.284717.86.06 0.78 0.314734.10.92 0.12 0.154741.21.08 0.14 0.154769.90.68 0.09 0.094781.00.40 0.05 0.094790.22.86 0.37 0.214812.50.77 0.10 0.124833.55.05 0.65 0.344854.60.62 0.08 0.124879.62.52 0.32 0.254904.80.43 0.06 0.094963.90.34 0.04 0.124977.91.26 0.16 0.155015.30.55 0.07 0.095022.70.71 0.09 0.125095.40.40 0.05 0.095103.50.31 0.04 0.095148.20.46 0.06 0.125383.60.31 0.04 0.095484.00.31 0.04 0.095545.114.98 1.93 0.745568.38.28 1.06 0.615584.62.52 0.32 0.185607.90.77 0.10 0.095617.83.26 0.42 0.25完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志5631.31.48 0.19 0.185683.22.46 0.32 0.185701.81.72 0.22 0.155721.50.43 0.06 0.096013.86 28 0.81 0.376033.62.55 0.33 0.216069.611.02 1.42 0.556091.03.75 0.48 0.256151.01.02 0.13 0.12完整細(xì)胞MALDIMeningo 5/M96255510Data:a0009.9 3 Jul 97 15:03 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:58,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志500.216.10 1.65 5.94 U509.30.96 0.10 0.52 U511.11.68 0.17 0.77 U516.0100.00 10.24 26.50 U520.16.50 0.67 2.51 U525.716.29 1.67 4.93 U532.086.19 8.82 21.23 U543.966.76 6.84 16.73 U551.24.52 0.46 1.87 U553.25.57 0.57 2.24 U558.11.44 0.15 0.83563.93.49 0.36 1.44 U566.110.84 1.11 3.09 U575.40.84 0.09 0.49582.017.18 1.76 4.99587.90.73 0.07 0.34598.30.59 0.06 0.34604.310.71 1.10 2.73620.714.90 1.53 2.76633.81.87 0.19 0.92636.10.83 0.09 0.31644.85.86 0.60 1.04652.90.33 0.03 0.25659.013.30 1.36 2.05 U666.822.73 2.33 5.85 U674.624.07 2.46 5.76690.269.23 7.09 13.51706.427.36 2.90 5.06 U715.320.15 2.06 4.60 U731.368.65 7.03 10.72746.58.86 0.91 1.35 U750.324.51 2.51 7.66 U753.224.65 2.52 6.16 U757.15.85 0.60 2.42 U762.019.36 1.98 3.83 U769.415.50 1.59 4.78 U773.017.49 1.79 3.71 U754.920.78 2.13 3.03801.214.75 1.51 2.51810.83.13 0.32 0.64825.71.56 0.16 0.58 U828.44.13 0.42 0.89 U836.40.75 0.08 0.31840.50.67 0.07 0.28855.13.76 0.38 0.61865.32.61 0.27 0.43880.42.94 0.30 0.64897.03.75 0.38 0.86 U902.42.58 0.26 0.83 U907.30.61 0.06 0.31913.61.77 0.18 0.52 U920.12.19 0.22 0.61 U930.51.98 0.20 0.37936.30.52 0.05 0.28942.96.94 0.71 1.41956.15.84 0.60 1.59967.51.42 0.15 0.34完整細(xì)胞MALDIMeningo 5/M96255510Data:a0009.9 3 Jul 97 15:03 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:58.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志985.8 2.36 0.24 0.52989.1 0.46 0.05 0.31995.1 1.51 0.15 0.311003.10.90 0.09 0.281018.25.30 0.54 0.701031.50.90 0.09 0.371043.12.74 0.28 0.49 U1047.90.97 0.10 0.40 U1056.54.84 0.50 0.741072.90.56 0.06 0.251077.21.20 0.12 0.281091.31.89 0.19 0.401101.31.44 0.15 0.491112.91.93 0.20 0.401126.83.91 0.40 0.771142.51.39 0.14 0.311155.911.72 1.20 2.701171.11.89 0.19 0.281178.27.26 0.74 1.651194.26.23 0.64 2.051202.00.53 0.05 0.341207.91.00 0.10 0.431215.83.36 0.34 0.701226.81.51 0.15 0.43 U1231.41.61 0.16 0.52 U1237.01.48 0.15 0.341245.40.99 0.10 0.431258.80.91 0.09 0.281274.61.13 0.12 0.341287.46.62 0.68 1.931295.91.14 0.12 0.281303.10.47 0.05 0.251309.91.08 0.11 0.431325.78.12 0.83 1.041342.00.50 0.05 0.281351.32.27 0.23 0.311367.01.31 0.13 0.341370.91.58 0.16 0.311386.71.11 0.11 0.431409.01.81 0.18 0.311431.41.15 0.12 0.281444.02.98 0.31 0.521456.61.13 0.12 0.401475.41.26 0.13 0.401492.93.55 0.36 0.491500.20.74 0.08 0.281507.52.33 0.24 0.311534.80.56 0.06 0.251556.84.03 0.41 0.521605.32.06 0.21 0.371626.62.13 0.22 0.521642.61.44 0.15 0.401665.01.41 0.14 0.311687.03.14 0.32 0.671726.50.63 0.06 0.281749.00.73 0.07 0.281780.80.57 0.06 0.28完整細(xì)胞MALDIMeningo 5/M96255510Data:a0009.9 3 Jul 97 15:03 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:58,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1787.51.47 0.15 0.251843.20.76 0.08 0.281857.42.60 0.27 0.371899.61.10 0.11 0.281937.30.48 0.05 0.251945.61.87 0.19 0.611953.21.29 0.13 0.341967.02.20 0.23 0.491983.02.46 0.25 0.83 U1990.11.61 0.16 0.61 U2027.41.41 0.14 0.282045.31.02 0.10 0.252077.13.20 0.33 0.432114.83.49 0.36 0.892153.71.04 0.11 0.2821973.8 0.47 0.05 0.252228.51.29 0.13 0.282238.30.60 0.06 0.282315.50.39 0.04 0.252341.50.77 0.08 0.252376.00.94 0.10 0.28完整細(xì)胞MALDIMeningo 10/M97251540Data:a0019.19 3 Jul 97 15:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+L1near High Power:65.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志512.31.580.280.67516.40.590.110.46520.70.530.090.46522.90.460.080.43 U526.322.76 4.056.95 U541.05.961.062.45 U544.5100.00 17.80 36.34 U552.914.75 2.623.62 U567.012.62 2.256.00582.922.52 4.018.64 U588.93.490.621.59 U605.511.51 2.055.64621.46.451.152.54 U627.64.140.741.75 U643.33.720.661.10659.55.811.031.84 U667.541.96 7.4715.07 U675.48.211.463.40 U690.718.02 3.215.82706.911.96 2.132.70 U716.315.87 2.825.88 U732.332.81 5.848.82 U737.411.63 2.074.38 U744.12.320.410.80 U751.415.92 2.838.95 U753.735.50 6.328.43 U770.714.92 2.663.86 U784.97.641.362.27 U789.44.210.751.72 U800.43.480.621.01812.50.960.170.37831.41.350.240.37 U833.90.510.090.43 U856.22.590.460.98882.71.750.310.40902.41.100.200.43944.40.900.160.64959.00.510.090.371006.4 0.600.110.341018.5 4.810.861.841055.9 6.231.112.18 U1063.0 0.790.140.55 U1077.5 1.060.190.491093.8 1.400.250.641100.0 1.160.210.371115.8 1.540.270.551130.3 0.870.160.371152.1 0.700.120.40 U1157.5 3.170.561.65 U1180.8 1.250.230.58 U1185.4 1.470.260.52 U1197.1 2.560.450.771211.6 0.400.070.341239.0 0.650.110.431289.1 1.390.250.611306.5 0.910.160.401414.6 1.080.190.34完整細(xì)胞MALDIMeningo 10/M97251540Data:a0019.19 3 Jul 97 15:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志1446.50.560.100.341471.80.920.160.431560.51.160.210.401607.21.870.330.981635.40.800.140.371644 91.550.280.671689.71.160.210.462692.91.240.220.492862.91.390.250.773313.01.070.190.405145.41.080.190.376424.72.650.470.646520.68.671.541.936619.546.42 8.268.58 U6657.26.341.131.47 U6686.60.850.150.46 U6695.91.040.180.43 U完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompatt MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000 (bin 56)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志504.20.950.030.18512.11.900.060.25519.05.480.180.28525.947.29 1.601.59535.50.950.030.18540.10.860.030.15544.1100.00 3.386.62 U549.45.700.190.49 U553.413.98 0.470.80 U566.410.68 0.360.74575.60.140.000.09578.30.720.020.12582.019.10 0.651.10588.47.060.240.49604.317.19 0.580.74609.50.320.010.09610.60.770.030.09621.25.430.180.21628.35.160.170.18634.70.450.020.09636.11.580.050.18645.77.780.260.37652.78.370.280.52657.83.800.130.28662.40.950.030.12667.042.22 1.431.93675.41.310.040.15678.10.630.020.09684.70.270.010.09690.412.58 0.420.58694.71.400.050.18706.211.67 0.390.49715.519.28 0.650.92731.545.70 1.541.41746.22.710.090.21754.024.03 0.810.80765.20.680.020.12770.79.140.310.58775.40.630.020.09781.01.810.060.15793.23.710.130.25807.90.770.030.12813.81.400.050.15817.31.990.070.15823.50.360.010.12832.50.900.030.15835.50.500.020.12847.90.500.020.12858.71.450.050.21864.20.270.010.09869.81.220.040.15874.01.000.030.15876.20.860.030.15879.93.620.120.31890.00.270.010.09897.03.570.120.31912.40.270.010.09完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志919.61.40 0.05 0.12931.92.76 0.09 0.15937.71.72 0.06 0.18945.62.17 0.07 0.15948.20.50 0.02 0.12956.62.13 0.07 0.18994.50.59 0.02 0.12998.30.32 0.01 0.091004.9 0.50 0.02 0.121017.3 0.72 0.02 0.121041.2 0.72 0.02 0.121057.2 0.50 0.02 0.091088.1 2.71 0.09 0.281096.9 2.71 0.09 0.151116.7 1.40 0.05 0.181132.2 0.50 0.02 0.121137.3 0.32 0.01 0.091156.2 2.44 0.08 0.211160.4 0.54 0.02 0.121163.6 3.35 0.11 0.311199.7 0.27 0.01 0.09122410.32 0.01 0.091248.4 0.50 0.02 0.121266.8 0.68 0.02 0.121274.2 1.22 0.04 0.151286.8 0.27 0.01 0.091298.3 1.27 0.04 0.151307.9 0.50 0.02 0.121323.0 0.45 0.02 0.091338.9 1.45 0.05 0.181362.8 1.18 0.04 0.121370.5 0.81 0.03 0.151379.3 0.50 0.02 0.121405.4 2.53 0.09 0.181428.9 0.77 0.03 0.121584.9 0.86 0.03 0.121644.9 0.50 0.02 0.121718.6 0.63 0.02 0.091785.9 0.50 0.02 0.091790.7 0.54 0.02 0.121998.1 0.45 0.02 0.092073.2 0.27 0.01 0.092137.0 0.45 0.02 0.092217.8 1.36 0.05 0.122227.6 0.27 0.01 0.092231.2 0.95 0.03 0.122235.6 2.22 0.07 0.212248.2 1.00 0.03 0.122266.6 0.86 0.03 0.152275.2 1.54 0.05 0.122292.8 2.62 0.09 0.152299.6 2.81 0.09 0.182317.3 1.04 0.04 0.152323.2 3.94 0.13 0.152332.4 0.45 0.02 0.092336.9 2.40 0.08 0.252342.9 0.86 0.03 0.12完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2348.82.81 0.09 0.212354.41.00 0.03 0.152358.90.27 0.01 0.092366.64.25 0.14 0.212371.81.09 0.04 0.122378.31.99 0.07 0.122383.82.90 0.10 0.182390.31.72 0.06 0.152401.95.20 0.18 0.282414.90.59 0.02 0.092418.15.66 0.19 0.182433.55.61 0.19 0.212448.07.96 0.27 0.282466.77.01 0.24 0.252477.54.30 0.15 0.312482.70.72 0.02 0.122490.31.09 0.04 0.152495.51.00 0.03 0.152504.03.44 0.12 0.212517.28.05 0.27 0.372525.86.74 0.23 0.462546.315.610.53 0.552563.510.000.34 0.462585.611.310.38 0.342601.43.76 0.13 0.252608.24.89 0.17 0.212619.323.120.78 0.802644.616.020.54 0.862660.622.900.77 0.772691.924.930.84 0.522707.71.22 0.04 0.152717.02.13 0.07 0.122748.246.381.57 0.922768.124.570.83 0.402824.127.870.94 0.522850.815.520.52 0.61 U2862.939.951.35 1.69 U2875.16.70 0.23 0.55 U2892.823.620.80 0.52 U2901.07.78 0.26 0.58 U2925.522.900.77 0.672945.027.470.93 0.522972.212.220.41 0.55 U2981.514.030.47 0.46 U3024.529.230.99 0.433039.120.540.69 0.433066.315.110.51 0.61 U3073.17.38 0.25 0.58 U3078.30.27 0.01 0.093103.631.541.07 0.70 U3112.014.300.48 0.58 U3127.97.19 0.24 0.373141.613.350.45 0.52 U3151.210.050.34 0.55 U3163.915.200.51 0.61 U3173.510.500.35 0.64 U3185.315.340.52 0.52 U完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志3194.93.440.12 0.313204.56.830.23 0.613219 532.26 1.09 0.61 U3244.226.92 0.91 0.61 U3283 718.55 0.63 0.583308.111.49 0.39 0.463331.016.15 0.55 0.403339.75.520.19 0.49 U3349.013.76 0.46 0.77 U3367.114.25 0.48 0.55 U3379.211.18 0.38 0.58 U3401.227.51 0.93 0.58 U3421.714.93 0.50 0.61 U3435.59.910.33 0.49 U3442.28.280.28 0.55 U3450.010.45 0.35 0.52 U3465.09.910.33 0.49 U3473.310.63 0.36 0.64 U3490.116.43 0.55 0.67 U3511.326.65 0.90 0.74 U3529.91.860.06 0.183554.632.08 1.08 0.743569.316.15 0.55 0.49 U3591.913.03 0.44 0.67 U3605.614.39 0.49 0.43 U3628.922.49 0.76 0.80 U3647.715.97 0.54 0.70 U3666.034.07 1.15 0.74 U3683.210.90 0.37 0.58 U3694.71.090.04 0.123716.625.43 0.86 1.04 U3731.012.31 0.42 0.52 U3750.117.69 0.60 0.743766.313.98 0.47 0.49 U3779.118.51 0.63 0.95 U3794.825.66 0.87 0.92 U3818.89.770.33 0.403870.953.03 1.79 0.61 U3881.06.560.22 0.49 U3893.312.08 0.41 0.61 U3908.18.600.29 0.403927.623.67 0.80 0.523948.41.950.07 0.153962.78.960.30 0.52 U3983.020.41 0.69 0.43 U4006.315.38 0.52 0.40 U4046.530.14 1.02 0.70 U4073.010.09 0.34 0.64 U4094.216.43 0.55 0.55 U4109.316.38 0.55 0.55 U4133.012.49 0.42 0.374156.710.27 0.35 0 46 U4171.417.24 0.58 0.64 U4185.411.40 0.39 0.64 U4205.712.22 0.41 0.58 U4220.48.690.29 0.40 U4237.018.24 0.62 0.52 U完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比峰值(mV) 標(biāo)志4261.017.063.580.55 U4275.320.590.700.67 U4322.413.710.460.524336.73.80 0.130.184371.029.681.000.464392.921.900.740.404438.820.410.690.494465.317.690.600.494533.843.481.470.494577.925.430.860.584623.418.100.610.434645.312.310.420.314666.617.600.590.80 U4695.716.700.560.52 U4706.19.05 0.310.46 U4717.24.89 0.170.214748.420.270.680.61 U4774.516.380.550.37 U4800.70.63 0.020.094808.53.71 0.130.214825.616.150.550.43 U4857.814.710.500.55 U4887.622.710.770.43 U4918.017.600.590.37 U4946.62.62 0.090.254973.917.420.590.525003.315.700.530.465018.04.25 0.140.255030.11.09 0.040.125058.329.190.990.555094.76.15 0.210.315127.811.000.370.46 U5144.114.570.490.55 U5159.71.99 0.070.155168.51.90 0.060.155186.222.170.750.435247.722.990.780.345277.90.68 0.020.125288.92.99 0.100.185311.617.100.580.405348.97.24 0.240.345361.44.30 0.150.285383.64.16 0.140.215400.92.08 0.070.215407.21.58 0.050.185433.612.260.410.285458.12.53 0.090.185468.65.57 0.190.255489.61.31 0.040.125506.42.76 0.090.155520.410.720.360.405547.911.000.370.285581.01.90 0.060.185605.16.65 0.220.215612.94.80 0.160.185629.20.45 0.020.095644.11.90 0.060.18完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25KratosKompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比 峰值(mV) 標(biāo)志5654.00.68 0.02 0.125664.02.71 0.09 0.185674.74.66 0.16 0.185711.14.98 0.17 0.155721.82.13 0.07 0.155736.13.85 0.13 0.185747.65.48 0.18 0.185770.61.67 0.06 0.125783.53.62 0.12 0.185807.31.72 0.06 0.095828.91.36 0.05 0.125849.98.46 0.29 0.215883.21.09 0.04 0.125917.34.12 0.14 0.185939.94.25 0.14 0.215953.02.58 0.09 0.185970.62.26 0.08 0.155981.51.76 0.06 0.155995.43.12 0.11 0.156035.18.87 0.30 0.216089.50.63 0.02 0.096129.51.00 0.03 0.126148.02.76 0.09 0.186179.21.00 0.03 0.126190.32.26 0.08 0.156221.625.52 0.86 0.776242.59.28 0.31 0.316268 713.53 0.46 0.216313.70.81 0.03 0.096323.52.76 0.09 0.256331.00.81 0.03 0.096418.61.95 0.07 0.156447.52.53 0.09 0.216521.30.95 0.03 0.126535.12.40 0.08 0.126558.00.45 0.02 0.096573.40.90 0.03 0.126581.00.45 0.02 0.096596.44.12 0.14 0.186649.51.49 0.05 0.126661.90.45 0.02 0.096692.810.09 0.34 0.376710.60.45 0.02 0.096726.92.67 0.09 0.216785.243.76 1.48 1.076847.62.31 0.08 0.186876.62.04 0.07 0.186908.80.68 0.02 0.126923.01.22 0.04 0.126937.10.63 0.02 0.09完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65.tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比 峰值(mV) 標(biāo)志500.645.924.17 6.65 U516.8100.00 9.07 8.95 U525.924.352.21 3.22 U533.321.391.94 2.85540.30.36 0.03 0.12545.058.345.29 6.89554.91.93 0.17 0.31556.30.34 0.03 0.18558.11.71 0.15 0.52 U560.11.98 0.18 0.64 U561.60.15 0.01 0.12567.07.03 0.64 1.32578.10.57 0.05 0.18583.15.83 0.53 0.95589.11.83 0.17 0.37593.70.54 0.05 0.12594.60.30 0.03 0.12602.70.20 0.02 0.12605.75.65 0.51 1.04613.00.51 0.05 0.18615.60.17 0.02 0.09621.93.31 0.30 0.46627.63.58 0.33 0.58633.50.17 0.02 0.09635.90.46 0.04 0.15645.75.39 0.49 0.70650.50.20 0.02 0.12654.61.01 0.09 0.18659.713.801.25 2.14667.810.160.92 1.47675.929.642.69 4.04687.70.10 0.01 0.09691.927.612.50 3.43700.20.69 0.06 0.18707.47.19 0.65 0.83 U716.812.191.11 1.35 U732.625.502.31 2.30 U738.211.851.07 1.62 U745.21.56 0.14 0.34754.033.433.03 2.48766.00.10 0.01 0.09770.78.64 0.78 0.77786.05.65 0.51 0.89790.00.10 0.01 0.09794.81.54 0.14 0.31800.12.47 0.22 0.37813.01.05 0.10 0.28817.00.05 0.00 0.09824.90.51 0.05 0.18830.10.36 0.03 0.18833.60.56 0.05 0.18838.50.85 0.08 0.15855.33.52 0.32 0.37867.53.13 0.28 0.25871.50.39 0.04 0.15873.70.19 0.02 0.12880.40.51 0.05 0.15完整細(xì)胞MALDIMeningo 20/M97251682Data:a003 9.19 3 Jul 97 16:28 Cal:tesc 25 Apr 97 11:25Kratos Kompact MAIDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志883.2 2.25 0.20 0.18893.7 0.63 0.06 0.12898.7 1.10 0.10 0.25905.6 0.19 0.02 0.12913.8 0.19 0.02 0.09915.6 0.27 0.02 0.12923.9 2.16 0.20 0.18927.9 0.71 0.06 0.18942.4 2.62 0.24 0.28952.6 0.51 0.05 0.15956.6 0.19 0.02 0.12966.3 1.81 0.16 0.28980.2 3.16 0.29 0.25998.3 0.32 0.03 0.121001.61.94 0.18 0.281010.60.12 0.01 0.091014.20.29 0.03 0.151018.81.35 0.12 0.311040.30.10 0.01 0.091042.70.71 0.06 0.211051.90.19 0.02 0.121056.84.02 0.36 0.581063.90.27 0.02 0.121078.82.71 0.25 0.461085.90.29 0.03 0.091091.60.52 0.05 0.211094.70.98 0.09 0.151100.30.83 0.08 0.211117.02.05 0.19 0.181121.80.78 0.07 0.281128.40.17 0.02 0.091132.22.60 0.24 0.341146.90.49 0.04 0.121153.30.17 0.02 0.091158.82.71 0.25 0.431164.00.98 0.09 0.181170.10.12 0.01 0.091175.31.44 0.13 0.281180.20.57 0.05 0.211189.31.37 0.12 0.251192.50.12 0.01 0.091204.70.47 0.04 0.121208.60.36 0.03 0.121210.60.12 0.01 0.091227.10.98 0.09 0.311234.70.34 0.03 0.121254.40.63 0.06 0.181259.10.79 0.07 0.181287.80.85 0.08 0.181292.91.35 0.12 0.281304.80.19 0.02 0.121315.10.19 0.02 0.121330.90.44 0.04 0.181339.90.56 0.05 0.211346.10.36 0.03 0.151375.40.39 0.04 0.151401.20.27 0.02 0.12完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1435.70.42 0.04 0.121469.60.19 0.02 0.121492.90.73 0.07 0.181513.80.17 0.02 0.091550.10.19 0.02 0.091558.70.69 0.06 0.151609.51.79 0.16 0.251623.50.34 0.03 0.121628.50.12 0.01 0.091663.00.34 0.03 0.121666.90.46 0.04 0.151687.80.86 0.08 0.251711.60.41 0.04 0.121714.30.32 0.03 0.121734.80.17 0.02 0.091753.30.12 0.01 0.091863.90.66 0.06 0.121877.00.17 0.02 0.091901.70.19 0.02 0.091951.10.12 0.01 0.091987.20.19 0.02 0.122056.50.30 0.03 0.152069.80.27 0.02 0.122093.50.66 0.06 0.212118.30.34 0.03 0.122136.21.69 0.15 0.152150.20.27 0.02 0.122156.30.54 0.05 0.122160.70.12 0.01 0.092166.00.25 0.02 0.122172.21.59 0.14 0.182185.80.39 0.04 0.122192.90.10 0.01 0.092198.20.10 0.01 0.092207.60.24 0.02 0.092215.60.24 0.02 0.092220.51.29 0.12 0.212225.80.10 0.01 0.092234.31.84 0.17 0.342244.60.98 0.09 0.212251.80.42 0.04 0.152279.20.36 0.03 0.152287.81.15 0.10 0.212301.00.44 0.04 0.122310.01.03 0.09 0.182321.40.49 0.04 0.152325.10.27 0.02 0.122331.90.27 0.02 0.122335.10.27 0.02 0.122339.71.44 0.13 0.182350.21.10 0.10 0.182362.21.23 0.11 0.182375.00.44 0.04 0.152381.02.08 0.19 0.212418.62.65 0.24 0.372428.80.47 0.04 0.182439.60.64 0.06 0.15完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志2447.50.850.080.182452.60.790.070.282460.13.310.300.252476.60.100.010.092483.20.420.040.152490.30.510.050.182495.50.290.030.122499.20.420.040.152507.80.320.030.122518.71.910.170.282531.50.170.020.092539.10.510.050.182548.28.590.780.372582.20.590.050.152590.40.830.080.152599.51.500.140.312604.30.170.020.092608.70.810.070.212614.50.440.040.152632.43.210.290.182645.55.170.470.462660.63.920.360.492673.30.100.010.092682.12.030.180.282693.43.550.320.372703.70.100.010.092711.10.640.060.152717.51.200.110.282728.42.000.180.182736.30.860.080.212741.20.420.040.122750.72.200.200.282759.10.240.020.092766.60.640.060.152772.50.250.020.122777.01.620.150.252786.50.360.030.122793.01.710.150.212805.02.230.200.342814.52.590.230.182834.60.320.030.122839.20.370.030.152843.71.540.140.252851.80.250.020.122862.45.870.530.642876.61.000.090.252892.35.500.500.462911.21.450.130.212917.30.100.010.092920.90.510.050.152928.61.390.130.182937.80.250.020.122945.01.670.150.252954.70.850.080.212963.53.640.330.402977.92.130.190.312990.82.980.270.28完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志3024.56.27 0.57 0.373036.50.32 0.03 0.123040.20.61 0.06 0.183045.92.13 0.19 0.253061.02.69 0.24 0.313077.81.47 0.13 0.213085.21.40 0.13 0.183103.16.78 0.61 0.493142.75.61 0.51 0.373150.10.91 0.08 0.283176.27.39 0.67 0.493194.96.48 0.59 0.403213.10.71 0.06 0.153222.71.22 0.11 0.253230.33.38 0.31 0.313251.30.66 0.06 0.123259.91.74 0.16 0.373277.74.80 0.44 0.46 U3287.52.54 0.23 0.40 U3297.33.33 0.30 0.40 U3326.66.81 0.62 0.463340.31.00 0.09 0.253349.63.92 0.36 0.46 U3360.63.65 0.33 0.34 U3373.70.30 0.03 0.093400.77.20 0.65 0.553421.73.13 0.28 0.313444.46.34 0.58 0.463461.61.42 0.13 0.153485.63.28 0.30 0.313508.54.45 0.40 0.463516.40.51 0.05 0.153524.80.56 0.05 0.153529.96.66 0.60 0.40 U3558.64.08 0.37 0.49 U3578.43.13 0.28 0.343609.57.91 0.72 0.373631.20.81 0.07 0.253642.62.23 0.20 0.283654.65.17 0.47 0.373676.34.53 0.41 0.463699.92.16 0.20 0.343714.36.26 0.57 0.40 U3737.42.82 0.26 0.37 U3748.40.46 0.04 0.153761.73.97 0.36 0.343777.91.50 0.14 0.373783.80.59 0.05 0.123791.30.30 0.03 0.123797.73.91 0.35 0.46 U3817.65.12 0.46 0.43 U3829.31.01 0.09 0.213847.43.28 0.30 0.493856.31.76 0.16 0.313870.40.98 0.09 0.153890.44.45 0.40 0.403905.72.93 0.27 0.25完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比總百分比峰值(mV) 標(biāo)志3940.112.16 1.10 0.52 U3970.41.84 0.17 0.43 U3982.41.12 0.10 0.153996.72.47 0.22 0.254010.51.72 0.16 0.284021.90.54 0.05 0.154039.94.79 0.43 0.584050.71.50 0.14 0.344064.05.56 0.50 0.284096.66.19 0.56 0.404133.04.62 0.42 0.344157.97.29 0.66 0.404224.17.59 0.69 0.404246.90.34 0.03 0.124257.32.00 0.18 0.254277.76.07 0.55 0.344300.62.99 0.27 0.43 U4343.59.74 0.88 0.40 U4371.02.28 0.21 0.434382.91.29 0.12 0.184394.85.33 0.48 0.55 U4420.64.75 0.43 0.43 U4442.62.64 0.24 0.464450.80.25 0.02 0.124462.21.96 0.18 0.374473.50.37 0.03 0.094487.53.52 0.32 0.314507.82.43 0.22 0.404547 96.80 0.62 0.374563.23.20 0.29 0.284583.02.52 0.23 0.434597 70.90 0.08 0.184605 42.74 0.25 0.314620.90.36 0.03 0.124640.28.47 0.77 0.434673.71.25 0.11 0.314686.00.81 0.07 0.254709.44.29 0.39 0.284742.59.33 0.85 0.344774.50.46 0.04 0.154786.93.28 0.30 0.184823.05.75 0.52 0.344851.93.58 0.3 3 0.314871.70.59 0.05 0.154895.54.99 0.45 0.584921.31.22 0.11 0.184939.33.21 0.29 0.284965.23.20 0.29 0.284991.32.42 0.22 0.285035.54.97 0.45 0.255046.21.17 0.11 0.285069.73.79 0.34 0.215093.31.08 0.10 0.155104.10.30 0.03 0.095109.60.30 0.03 0.095119.70.73 0.07 0.185129.20.24 0.02 0.09完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.193 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志5138.01.25 0.11 0.155154.31.52 0.14 0.315162.41.76 0.16 0.285178.70.83 0.08 0.125213.52.10 0.19 0.255234.70.68 0.06 0.155242.20.41 0.04 0.125253.20.51 0.05 0.125272.41.15 0.10 0.125288.22.10 0.19 0.285303.40.54 0.05 0.155320.63.79 0.34 0.315355.11.39 0.13 0.185364.10.47 0.04 0.155371.80.39 0.04 0.155392.60.86 0.08 0.155411.40.46 0.04 0.125427.41.17 0.11 0.155461.60.83 0.08 0.125470.70.59 0.05 0.155488.92.42 0.22 0.185522.51.40 0.13 0.215531.00.78 0.07 0.185541.50.51 0.05 0.125564.81.37 0.12 0.125574.00.36 0.03 0.095585.30.22 0.02 0.095597.30.24 0.02 0.095617.80.47 0.04 0.155642.00.30 0.03 0.125658.30.83 0.08 0.185668.30.24 0.02 0.095722.50.39 0.04 0.125733.30.66 0.06 0.125745.40.30 0.03 0.095762.70.22 0.02 0.095808.70.52 0.05 0.095839.01.07 0.10 0.215862.20.17 0.02 0.095913.00.32 0.03 0.125919.50.17 0.02 0.095956.71.57 0.14 0.126017.40.86 0.08 0.186089.50.25 0.02 0.126108.00.22 0.02 0.096130.20.56 0.05 0.156142.80.68 0.06 0.186178.40.57 0.05 0.156273.20.32 0.03 0.126297.20.30 0.03 0.096319.71.32 0.12 0.126394.40.47 0.04 0.096533.60.24 0.02 0.096554.20.17 0.02 0.096625.60.30 0.03 0.096707.50.32 0.03 0.126718.30.17 0.02 0.09完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志6753.30.59 0.05 0.186790.620.09 1.82 1.356841.40.41 0.04 0.126864.10.39 0.04 0.126879.81.20 0.11 0.156893.90.64 0.06 0.1權(quán)利要求
1．一種鑒定微生物的方法，其特征在于對于一系列已知微生物，提供基體輔助激光解吸電離飛行時間質(zhì)譜(MALDI-TOF-MS)數(shù)據(jù)庫；制備未鑒定微生物樣品并且利用MALDI-TDF-MS獲得質(zhì)譜數(shù)據(jù)；利用適當(dāng)?shù)谋容^裝置將上述獲得的質(zhì)譜數(shù)據(jù)與數(shù)據(jù)庫進(jìn)行比較以鑒定具有相同或相似質(zhì)譜數(shù)據(jù)的已知微生物。
2．用于篩選微生物的裝置，其特征在于該裝置包括獲取生物樣品MALDI-TOF-MS質(zhì)譜數(shù)據(jù)的質(zhì)譜裝置；包括一系列微生物MALDI-TOF-MS質(zhì)譜數(shù)據(jù)的數(shù)據(jù)庫裝置；以及將樣品質(zhì)譜數(shù)據(jù)與數(shù)據(jù)庫數(shù)據(jù)進(jìn)行比較從而可對樣品進(jìn)行分類/鑒定的比較裝置。
3．權(quán)利要求1或2的方法或裝置，其特征在于比較裝置是計算機。
4．前述任一權(quán)利要求的方法或裝置，其特征在于數(shù)據(jù)庫裝置包括以強度與質(zhì)譜比曲線的圖形形式記錄下來的質(zhì)譜數(shù)據(jù)。
5．前述任一權(quán)利要求的方法或裝置，其特征在于數(shù)據(jù)庫裝置包括以數(shù)字或模擬形式記錄的圖形、數(shù)值或電子格式的質(zhì)譜數(shù)據(jù)，且比較裝置相應(yīng)構(gòu)建。
6．前述任一權(quán)利要求的方法或裝置，其特征在于根據(jù)每一微生物的屬對數(shù)據(jù)庫中的質(zhì)譜數(shù)據(jù)進(jìn)行編組，進(jìn)一步的劃分則對應(yīng)于微生物的株。
7．前述任一權(quán)利要求的方法或裝置，其特征在于為了保持樣品細(xì)胞的完整性，在進(jìn)行MALDI-TOF-MS分析之前，從培養(yǎng)物中取出細(xì)胞并將其放入含基體的樣品盤內(nèi)或?qū)⒓?xì)胞與基體混合來制備未鑒定微生物的樣品。
8．前述任一權(quán)利要求的方法或裝置，其特征在于制備樣品基體混合物并且利用激光能量對其進(jìn)行轟擊以產(chǎn)生各種氣相離子，將所產(chǎn)生的離子脈沖輸送至飛行管道內(nèi)進(jìn)行正離子和/或負(fù)離子鑒定。
9．前述任一權(quán)利要求的方法或裝置，其特征在于通過離子碎片的質(zhì)荷比檢測每種存在的離子形式。
10．權(quán)利要求9的方法或裝置，其特征在于根據(jù)特定離子平均分子量所對應(yīng)峰的中心位置確定每一質(zhì)譜峰的質(zhì)荷比。
11．前述任一權(quán)利要求的方法或裝置，其特征在于通過對樣品的多次激光轟擊來獲得質(zhì)譜；對于同一樣品而言，每次轟擊的位置和/或能量是不同的。
12．前述任一權(quán)利要求的方法或裝置，其特征在于應(yīng)用線性分析來提高數(shù)據(jù)靈敏度。
13．用于前述任一權(quán)利要求的方法或裝置中、包括對已知微生物進(jìn)行MALDI-TOF-MS分析獲得的質(zhì)譜數(shù)據(jù)的微生物數(shù)據(jù)庫。
14．權(quán)利要求13的數(shù)據(jù)庫，包括至少一種以下微生物大腸桿菌8110大腸桿菌10214 K12 λ產(chǎn)氣克雷伯氏菌8172弗氏檸檬酸桿菌9750金黃色葡萄球菌B1金黃色葡萄球菌B2抗methicillin的金黃色葡萄球菌(MRSA)01/270030金黃色葡萄球菌(MRSA)02/270238*艱難梭菌NCTC 11204*艱難梭菌NCTC 11206*產(chǎn)氣熒膜梭菌*破傷風(fēng)梭菌瑪爾摩分枝桿菌0036C鳥分枝桿菌-intracellulare-scrofulaceum 0352C鳥分枝桿菌-intracellulare.0589C蟾分枝桿菌0545C奈瑟氏球菌M96255506奈瑟氏球菌M96255510奈瑟氏球菌M97251540奈瑟氏球菌M97251545奈瑟氏球菌M97251682其中數(shù)據(jù)庫中的質(zhì)譜數(shù)據(jù)如下完整細(xì)胞MALDIKRATOS DB Set大腸桿菌8110Data:std0001.1 24 Jul 97 16:26 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志510.45.70 0.63 2.21519.42.46 0.27 0.89525.55.77 0.63 1.69530.90.71 0.08 0.49543.485.639.41 31.16551.72.19 0.24 1.04565.156.596.22 19.00581.216.731.84 6.10 U587.310.331.13 4.32 U603.711.791.29 5.12609.70.97 0.11 0.37619.63.14 0.35 0.89 U625.53.38 0.37 1.26 U644.00.93 0.10 0.34651.20.56 0.06 0.34657.753.235.85 21.63 U665.824.082.65 8.61 U673.870.647.76 27.18689.630.783.38 10.75705.85.38 0.59 1.72 U715.411.031.21 3.16 U728.347.115.18 15.47736.51.99 0.22 0.70 U744.228.913.18 9.87 U750.431.443.45 8.39 U766.528.313.11 9.01 U774.62.15 0.24 1.07 U782.09.74 1.07 2.63 U791.04.09 0.45 1.23 U794.22.51 0.28 0.74 U812.64.93 0.54 1.04831.92.24 0.25 0.49845.34.89 0.54 1.65853.21.37 0.15 0.37863.81.15 0.13 0.46 U869.94.18 0.46 1.38 U885.010.831.19 2.85901.12.35 0.26 1.07916.71.78 0.20 0.40932.80.64 0.07 0.34974.59.61 1.06 2.91987.53.03 0.33 0.371004.8 2.15 0.24 0.401031.6 1.80 0.20 0.371059.7 2.33 0.26 0.921080.3 2.10 0.23 0.461103.4 82.799.09 29.691119.5 0.93 0.10 0.401125.2 3.66 0.40 1.291141.4 1.14 0.13 0.371147.5 1.54 0.17 0.67 U1153.5 2.15 0.24 0.67 U1176.1 1.44 0.16 0.341188.4 7.66 0.84 1.72 U1198.2 0.79 0.09 0.43 U1213.3 1.62 0.18 0.491232.8 100.00 10.9935.48完整細(xì)胞MALDIKRATOS DB Set大腸桿菌8110Data:stdD001.1 24 Jul 97 16:26 Cal:july97v3 24 Jul 97 11:05Ktatos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1254.17.580.832.301270.52.440.271.13 U1276.62.330.260.77 U1292.11.910.210.801314.64.410.480.891361.956.31 6.1920.991384.34.470.491.191400.23.180.350.861421.80.880.100.431467.01.720.190.551490.67.100.782.211592.50.630.070.34完整細(xì)胞MALDIKRATOS D8 Set大腸桿菌10214 K 121 amData:std0003.3 24 Jul 97 16:28 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60.tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比 峰值(mV) 標(biāo)志510.6 8.421.46 2.24519.0 9.511.65 2.30 U524.4 44.43 7.70 9.34 U539.4 28.14 4.87 4.93 U543.1 100.00 17.32 21.11 U551.5 31.48 5.45 7.08564.9 36.20 6.27 7.05580.9 10.33 1.79 1.69587.6 5.941.03 1.47603.7 7.041.22 1.26609.5 1.070.19 0.18618.4 8.021.39 0.77629.5 0.770.13 0.34640.7 5.781.00 0.92648.8 0.430.07 0.21657.7 28.64 4.96 6.68 U666.0 32.05 5.55 6.92 U673.8 28.00 4.85 6.56689.1 16.38 2.84 3.28706.8 8.081.40 0.89714.4 11.31 1.96 2.57729.8 6.441.12 1.10736.0 3.090.53 0.67744.4 1.620.28 0.31752.2 3.910.68 0.70762.8 1.480.26 0.40779.9 0.730.13 0.21788.6 11.11 1.92 1.32798.4 0.850.15 0.28801.4 0.490.08 0.25814.0 3.490.61 0.46827.0 1.760.31 0.34833.0 1.570.27 0.40846.9 3.840.66 0.67854.9 2.500.43 0.46863.2 2.570.44 0.37869.3 1.090.19 0.25885.3 8.611.49 0.95995.1 0.890.15 0.25900.5 1.530.27 0.37911.0 1.200.21 0.43921.6 1.840.32 0.40926.2 0.910.16 0.21933.6 1.000.17 0.25955.7 1.000.17 0.28973.6 3.900.68 0.58999.7 1.540.27 0.401015.6 2.620.45 0.281031.0 2.760.48 0.311037.6 0.340.06 0.181044.3 1.040.18 0.211054.1 0.740.13 0.251059.0 1.190.21 0.311065.5 1.370.24 0.281090.6 0.910.16 0.181103.4 10.98 1.90 1.191120.1 2.270.39 0.37 U完整細(xì)胞MALDIKRATOS DB Set大腸桿菌10214 K 121 amData:std0003.3 24 Jul 97 16:28 Cal:july97v3 24.Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60.tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比 峰值(mV) 標(biāo)志1128.71.87 0.32 0.34 U1154.27.75 1.34 1.231174.85.20 0.90 0.641192.70.37 0.06 0.181197.61.04 0.18 0.371232.47.42 1.29 1.501248.40.90 0.16 0.211253.40.41 0.07 0.181272.21.20 0.21 0.311279.31.15 0.20 0.371293.80.73 0.13 0.181313.63.23 0.56 0.341322.91.83 0.32 0.281339.02.00 0.35 0.281361.68.82 1.53 1.531378.43.98 0.69 0.551444.30.60 0.10 0.181453.00.68 0.12 0.251492.14.03 0.70 0.551532.11.29 0.22 0.311545.81.61 0.28 0.211566.71.01 0.18 0.181579.80.63 0.11 0.211638.50.85 0.15 0.181646.10.71 0.12 0.181749.20.44 0.08 0.181904.90.80 0.14 0.251956.31.50 0.26 0.28完整細(xì)胞MALDIKRATOS DB Set產(chǎn)氣克雷氏菌8172Data:std0013.13 24 Jul 97 16:39 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志519.02.340.511.32524.48.781.914.35539.23.550.771.53 U543.44.200.912.30 U552.03.430.751.84565.414.24 3.104.69575.34.290.931.47588.00.950.210.46591.51.580.340.52600.20.910.200.49635.70.880.190.58640.42.450.530.89651.51.610.350.80 U658.0100.00 21.77 45.25 U667.71.740.380.74673.821.48 4.6810.57 U680.03.420.751.50 U688.64.250.921.41705.31.930.420.67 U710.31.360.300.89 U714.11.050.230.49 U727.85.751.252.36 U736.02.220.480.61 U750.46.131.332.48761.32.860.620.77768.80.580.130.46774.91.140.250.67 U778.61.350.290.67 U782.81.350.290.67 U790.53.410.741.04 U795.50.900.200.74 U803.01.650.360.74814.84.591.001.69822.92.020.440.77830.51.130.250.86836.02.300.500.89 U840.61.110.240.80 U847.53.220.701.56 U856.31.410.310.67862.91.220.270.74 U869.012.21 2.665.15 U885.08.971.951.96911.94.941.081.56 U923.01.520.330.70 U927.01.130.250.70 U933.41.480.320.61962.71.170.260.52974.80.910.200.58986.62.670.580.83 U991.01.000.220.58 U1000.0 6.351.382.451021.9 5.211.132.54 U1026.7 1.630.360.58 U1043.7 4.360.951.231058.7 2.390.520.551075.1 1.140.250.74 U1080.7 6.211.352.85 UKRATOS DB Set產(chǎn)氣克雷氏菌8172Data:std0013.13 24 Jul 97 16:39 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1090.00.83 0.180.581096.51.42 0.310.67 U1102.22.33 0.511.07 U1108.52.92 0.641.13 U1117.61.25 0.270.43 U1126.80.89 0.190.46 U1132.21.55 0.340.61 U1153.914.753.215.361167.00.91 0.200.58 U1176.119.084.159.28 U1192.73.13 0.681.10 U1197.99.71 2.114.53 U1222.82.64 0.570.521237.11.87 0.410.461264.82.81 0.610.611278.91.50 0.330.521291.54.87 1.061.56 U1300.61.56 0.340.64 U1306.11.05 0.230.67 U1310.51.75 0.380.64 U1319.10.61 0.130.43 U1324.92.69 0.590.98 U1339.41.50 0.330.74 U1347.41.28 0.280.55 U1361.64.44 0.971.161376.30.94 0.210.431392.14.19 0.910.701408.02.67 0.580.641437.52.77 0.600.55 U1452.23.58 0.780.49 U1476.42.28 0.500.58 U1491.03.29 0.720.74 U1503.01.84 0.400.58 U1518.12.36 0.510.55 U1538.82.15 0.470.49 U1558.84.01 0.870.74 U1612.21.28 0.280.431620.53.96 0.861.501670.30.67 0.150.43 U1678.41.62 0.350.46 U1706.42.93 0.640.95 U1721.62.04 0.440.70 U1733.42.17 0.470.49 U1750.02.90 0.631.01 U1773.72.98 0.650.921790.91.91 0.420.551853.81.29 0.280.461879.04.41 0.960.861898.70.81 0.180.46 U1927.23.73 0.810.52 U1965.13.36 0.730.612008.51.83 0.400.552084.53.35 0.730.462098.71.89 0.410.432171.61.55 0.340.43 U2191.41.38 0.300.492295.21.97 0.430.49 U完整細(xì)胞MALDIKRATOS DB Set產(chǎn)氣克雷氏菌8172Data:std0013.13 24 Jul 97 16:39 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60.tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比峰值(mV) 標(biāo)志2388.8 1.10 0.240.432402.2 0.67 0.150.43完整細(xì)胞MALDIKRATOS DB Set弗氏檸檬酸桿菌9750Data:std0015.15 24 Jul 97 16:42 Ca1:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志502.10.200.02 0.21510.43.460.42 1.35518.818.83 2.29 5.73 U524.442.51 5.18 13.63 U539.621.22 2.58 7.20 U543.622.28 2.71 7.11 U551.572.69 8.85 21.66 U565.425.50 3.11 5.42 U569.65.120.62 2.67 U578.920.95 2.55 4.53588.95.040.61 2.14600.51.210.15 0.61604.65.220.64 1.29612.11.300.16 0.70618.67.820.95 2.57 U623.16.210.76 1.56 U630.20.400.05 0.31640.712.45 1.52 2.94653.11.190.14 0.40657.721.56 2.63 8.06667.913.93 1.70 3.80 U673.819.62 2.39 6.99 U684.11.280.16 0.61690.18.931.09 1.81707.63.800.46 1.13 U714.69.491.16 2.79 U729.68.591.05 1.99736.21.940.24 0.92742.13.150.38 0.70752.45.570.68 1.90762.66.060.74 1.87 U768.13.050.37 1.13 U774.40.870.11 0.43 U778.81.430.17 0.58 U784.61.800.22 0.77 U789.15.220.64 1.10 U796.01.620.20 0.55 U803.50.520.06 0.31807.50.620.08 0.40 U813.24.970.60 1.01 U822.42.110.26 0.61 U830.24.280.52 0.98839.81.450.18 0.52847.53.150.38 0.92856.02.070.25 0.74 U863.24.730.58 1.19 U873.20.780.09 0.46884.16.270.76 1.23 U892.04.420.54 0.74 U911.03.610.44 0.86929.61.450.18 0.34947.32.110.26 0.31962.12.030.25 0.43969.80.790.10 0.31973.90.340.04 0.21986.91.460.18 0.37991.00.500.06 0.21完整細(xì)胞MALDIKRATOS DB Set弗氏檸檬酸桿菌9750Data:std0015.15 24 Jul 97 16:42 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1000.33.25 0.40 0.671009.00.95 0.12 0.281021.32.00 0.24 0.671029.80.85 0.10 0.371038.90.72 0.09 0.281045.31.02 0.12 0.341051.10.59 0.07 0.311062.71.68 0.21 0.401073.51.14 0.14 0.491090.62.82 0.34 0.701106.33.26 0.40 0.64 U1116.01.01 0.12 0.40 U1133.12.26 0.27 0.461153.93.73 0.45 0.831176.12.95 0.36 0.581182.90.32 0.04 0.211202.51.65 0.20 0.311214.90.83 0.10 0.311263.11.59 0.19 0.431270.50.51 0.06 0.211278.90.98 0.12 0.251292.10.86 0.10 0.371300.30.72 0.09 0.211306.80.68 0.09 0.211331.12.08 0.25 0.311341.10.81 0.10 0.251361.91.29 0.16 0.281379.81.70 0.21 0.281414.40.65 0.08 0.281419.30.59 0.07 0.311451.90.64 0.08 0.251492.44.12 0.50 1.161507.83.16 0.38 0.801531.00.50 0.06 0.251540.60.48 0.06 0.211574.50.65 0.08 0.251621.719.56 2.38 6.53 U1637.713.82 1.68 4.04 U1659.93.22 0.39 1.041679.21.63 0.20 0.401706.80.44 0.05 0.211722.41.34 0.16 0.311750.816.69 2.03 5.76 U1767.012.39 1.51 3.34 U1789.32.05 0.25 0.831804.51.06 0.13 0.281880.72.49 0.30 0.741904.56.29 0.77 0.671926.40.35 0.04 0.211957.60.98 0.12 0.211973.92.15 0.26 0.282010.61.48 0.18 0.432028.01.43 0.17 0.282049.31.23 0.15 0.312070.70.76 0.09 0.212084.10.64 0.08 0.282169.82.29 0.28 0.28完整細(xì)胞MALDIKRATOS DB Set弗氏檸檬酸桿菌9750Data:std0015.15 24 Jul 97 16:42 Cal:july97v3 24 Jul 97 11:05Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2222.52.39 0.29 0.342240.81.03 0.13 0.252256.91.61 0.20 0.342318.74.11 0.50 0.372370.40.88 0.11 0.252414.73.11 0.38 0.282478.21.34 0.16 0.40 U2492.33.51 0.43 0.61 U2542.12.85 0.35 0.342596.12.24 0.27 0.312682.01.48 0.18 0.252708.01.87 0.23 0.282733.61.77 0.22 0.282782.71.00 0.12 0.212816.63.42 0.42 0.312874.51.64 0.20 0.342899.92.48 0.30 0.282946.30.82 0.10 0.252991.11.52 0.19 0.253087.42.11 0.26 0.283162.95.73 0.70 0.893188.42.41 0.29 0.373257.01.81 0.22 0.343400.2100.00 12.18 19.61 U3423.922.22 2.71 3.52 U3501.70.45 0.05 0.213538.72.18 0.26 0.253586.02.16 0.26 0.253627.41.16 0.14 0.283769.81.49 0.18 0.283824.50.63 0.08 0.253874 85.38 0.66 0.553974.81.63 0.20 0.214769.31.88 0.23 0.435451.242.34 5.16 7.357739.53.92 0.48 0.61金黃色萄萄球菌分離物營養(yǎng)瓊脂B1Data:a0001.1 17 Jul 97 17:18 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志511.30.88 0.19 0.49 U517.11.64 0.35 0.46 U528.74.06 0.87 1.16543.41.16 0.25 0.52 U558.12.81 0.60 0.80 U563.96.13 1.31 2.51 U580.410.51 2.24 3.80587.30.62 0.13 0.46595.82.29 0.49 0.86 U604.11.57 0.34 0.67 U620.32.24 0.48 1.01 U623.62.19 0.47 0.92 U638.50.70 0.15 0.49 U642.11.71 0.36 0.86 U653.41.93 0.41 0.80 U658.512.16 2.60 5.88 U668.53.09 0.66 1.16 U674.463.67 13.60 30.97 U684.71.25 0.27 0.74 U690.4100.00 21.35 43.78 U706.456.30 12.02 24.42722.45.15 1.10 2.36769.43.13 0.67 0.80785.71.98 0.42 1.13 U791.66.72 1.43 2.85 U801.70.82 0.18 0.52 U807.66.01 1.28 2.33 U823.80.97 0.21 0.77 U827.62.80 0.60 1.13 U832.80.62 0.13 0.58 U847.35.21 1.11 1.81865.94.15 0.89 1.23881.84.72 1.01 2.30 U886.08.92 1.90 4.14 U896.23.32 0.71 2.39 U902.220.09 4.29 8.79 U918.717.72 3.78 6.83934.54.79 1.02 2.39985.50.79 0.17 0.431003.4 4.86 1.04 1.041020.3 5.48 1.17 1.781037.0 3.53 0.75 1.071053.5 1.76 0.38 0.741082.5 2.25 0.48 0.641097.5 3.35 0.71 1.041115.1 8.01 1.71 2.421130.3 6.60 1.41 2.51 U1147.6 4.95 1.06 1.29 U116 3.6 1.24 0.27 0.58 U1196.5 0.89 0.19 0.461225.4 2.82 0.60 0.641250.4 4.51 0.96 0.701276.9 1.76 0.38 0.46 U1325.7 4.04 0.86 0.83 U1342.7 3.43 0.73 1.29 U1356.6 3.09 0.66 0.52 U1372.3 2.17 0.46 0.49 U金黃色葡萄球菌分離物營養(yǎng)瓊脂B1Data:a0001.1 17 Jul 97 17:18 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1388.10.91 0.19 0.46 U1426.42.40 0.51 0.641458.03.16 0.68 0.611473.21.29 0.28 0.551518.63.02 0.64 0.431534.81.69 0.36 0.551554.91.75 0.37 0.52 U1569.11.68 0.36 0.52 U1827.31.01 0.22 0.551841.91.00 0.21 0.462000.72.13 0.45 0.432100.52.59 0.55 0.432387.01.59 0.34 0.462516.31.38 0.29 0.492814.53.14 0.67 0.46金黃色葡萄球菌分離物營養(yǎng)瓊脂B2Data:a0003.3 17 Jul 97 17:22 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Powar:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志500.84.74 0.57 1.35 U505.51.19 0.14 0.61512.39.28 1.11 1.62 U516.85.15 0.62 1.29 U526.612.17 1.46 2.67 U530.515.58 1.87 2.57 U543.645.57 5.48 8.52552.91.29 0.16 0.74557.64.15 0.50 1.29 U563.720.99 2.52 4.50 U569.33.81 0.46 1.44575.94.84 0.58 1.16 U581.127.92 3.35 4.14 U596.74.15 0.50 0.77 U603.411.88 1.43 1.59 U620.59.11 1.09 1.93 U622.64.52 0.54 1.78 U625.25.06 0.61 1.62 U635.94.64 0.56 1.10645.26.06 0.73 1.10650.83.37 0.41 0.95 U659.532.49 3.90 5.82 U666.821.15 2.54 4.07 U674.471.60 8.60 17.83684.25.63 0.68 1.44690.4100.00 12.02 22.86706.447.63 5.72 11.64715.30.34 0.04 0.21722.66.47 0.78 1.23731.31.10 0.13 0.49741.61.40 0.17 0.40 U746.54.67 0.56 0.74 U757.40.39 0.05 0.21764.11.45 0.17 0.37772.011.04 1.33 1.78790.522.67 2.72 2.76807.310.23 1.23 1.99 U811.64.49 0.54 1.16 U819.20.26 0.03 0.21827.17.52 0.90 1.23 U833.93.85 0.46 0.95 U846.023.74 2.85 3.98864.26.84 0.82 1.90 U869.25.88 0.71 1.13 U880.44.84 0.58 1.07 U886.09.39 1.13 2.39 U894.22.36 0.28 0.46 U902.419.79 2.38 3.52 U911.03.42 0.41 1.04 U918.48.74 1.05 1.56 U937.14.28 0.51 0.55953.42.61 0.31 0.55963.73.55 0.43 0.49982.94.70 0.56 0.461000.7 3.85 0.46 0.521015.4 2.52 0.30 0.61 U1021.2 3.64 0.44 0.70 U金黃色萄萄球菌分離物營養(yǎng)瓊脂B2Dat.a:a0003.3 17 Jul 97 17:22 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1040.66.18 0.74 0.581053.20.71 0.09 0.211061.50.99 0.12 0.211070.12.25 0.27 0.52 U1078.53.88 0.47 0.40 U1097.85.73 0.69 0.671113.98.46 1.02 1.721131.04.44 0.53 0.701153.75.13 0.62 0.491175.33.44 0.41 0.401191.21.48 0.18 0.281199.40.78 0.09 0.281218.23.15 0.38 0.431233.71.75 0.21 0.401249.04.88 0.59 0.611261.12.27 0.27 0.521278.61.49 0.18 0.341285.12.08 0.25 0.341308.62.33 0.28 0.491324.44.45 0.54 0.701344.02.34 0.28 0.431353.82.56 0.31 0.401373.32.04 0.24 0.401390.61.54 0.18 0.281412.23.31 0.40 0.281428.63.71 0.45 0.341455.92.04 0.24 0.251477.22.82 0.34 0.341483.01.32 0.16 0.211496.90.56 0.07 0.211524.94.16 0.50 0.341536.00.58 0.07 0.211545.22.28 0.27 0.431569.91.05 0.13 0.211599.22.52 0.30 0.281641.51.72 0.21 0.401655.73.84 0.46 0.431712.81.07 0.13 0.281748.22.04 0.25 0.281769.22.08 0.25 0.311793.10.95 0.11 0.211804.41.70 0.20 0.281829.81.86 0.22 0.211870.50.75 0.09 0.211919.01.77 0.21 0.212019.30.74 0.09 0.252057.32.06 0.25 0.402149.71.94 0.23 0.252167.81.76 0.21 0.282184.51.18 0.14 0.312206.20.58 0.07 0.212266.61.16 0.14 0.312451.21.19 0.14 0.252513.90.98 0.12 0.252535.81.35 0.16 0.212779.03.37 0.41 0.312852.81.96 0.24 0.43金黃色葡萄球菌分離物營養(yǎng)瓊脂B2Data:a0003.3 17 Jul 97 17:22 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+LinMear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2868.52.52 0.30 0.462933.21.29 0.16 0.253046.92.07 0.25 0.313093.60.77 0.09 0.253122.11.19 0.14 0.213184.71.45 0.17 0.253248.60.69 0.08 0.213464.44.41 0.53 0.253534.91.34 0.16 0.313552.91.44 0.17 0.255533.12.24 0.27 0.406897.08.05 0.97 0.83完整細(xì)胞MALDIMRSA 01/270030Data:a0001.1 3 Jul 97 17:50 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志502.50.35 0.07 0.12517.90.35 0.07 0.12533.50.29 0.06 0.12536.60.73 0.15 0.18558.70.62 0.13 0.21565.00.44 0.09 0.18581.10.23 0.05 0.12582.20.41 0.09 0.18584.70.35 0.07 0.12596.70.83 0.17 0.15599.90.15 0.03 0.09601.60.15 0.03 0.09622.40.25 0.05 0.12630.40.23 0.05 0.12633.50.12 0.03 0.09637.80.12 0.03 0.09639.50.97 0.20 0.31655.12.49 0.52 0.28659.74.52 0.94 0.83662.60.15 0.03 0.09671.25.70 1.18 0.86 U675.635.98 7.48 5.02 U687.20.89 0.19 0.25691.784.81 17.63 11.40700.70.15 0.03 0.12707.7100.00 20.78 10.78723.630.72 6.38 3.92732.80.59 0.12 0.12753.50.62 0.13 0.12763.91.12 0.23 0.18766.00.06 0.01 0.09767.30.12 0.03 0.09774.60.77 0.16 0.18777.00.44 0.09 0.18779.60.21 0.04 0.09787.61.47 0.31 0.34792.40.15 0.03 0.09794.00.15 0.03 0.09803.30.79 0.16 0.25813.30.25 0.05 0.12817.30.12 0.03 0.09819.20.15 0.03 0.09824.60.87 0.18 0.18831.40.21 0.04 0.12834.70.54 0.11 0.18846.20.23 0.05 0.12848.20.33 0.07 0.12849.80.91 0.19 0.28855.10.17 0.03 0.12861.70.89 0.19 0.18865.31.62 0.34 0.28871.50.37 0.08 0.15876.20.46 0.09 0.12877.90.23 0.05 0.12881.53.83 0.80 0.46 U887.42.61 0.54 0.58 U897.35.16 1.07 0.77 U完整細(xì)胞MALDIMRSA 01/270030Data:a0001.1 3 Jul 97 17:50 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志903.618.45 3.83 2.24 U913.63.270.68 0.67 U919.929.28 6.09 3.09 U926.20.540.11 0.18935.722.57 4.69 2.67953.12.300.48 0.46955.80.230.05 0.09958.40.330.07 0.12970.40.210.04 0.09977.50.990.21 0.18982.90.230.05 0.121003.4 0.730.15 0.181020.3 0.580.12 0.181023.0 0.170.03 0.121030.9 0.150.03 0.091033.6 0.310.06 0.121048.9 0.460.09 0.151054.1 0.310.06 0.121074.1 1.060.22 0.341095.0 0.370.08 0.151097.2 2.050.43 0.211106.0 0.150.03 0.091109.4 1.780.37 0.401114.8 5.531.15 0.491131.3 14.24 2.96 1.261141.5 0.150.03 0.091147.6 7.091.47 0.891160.1 0.540.11 0.151163.3 2.780.58 0.311170.8 2.220.46 0.371187.6 0.480.10 0.151190.9 0.370.08 0.151196.5 0.150.03 0.091202.4 0.150.03 0.091214.2 0.480.10 0.181227.4 0.330.07 0.121240.0 0.150.03 0.091242.0 0.120.03 0.091248.0 0.500.10 0.151253.4 0.480.10 0.151298.3 0.660.14 0.211308.2 0.480.10 0.151311.7 0.230.05 0.11323.0 0.680.14 0.181327.5 3.480.72 0.401335.0 0.540.11 0.181343.7 7.611.58 0.671359.3 4.190.87 0.431371.9 0.600.12 0.181375.8 5.351.11 0.611387.7 0.750.16 0.181393.4 1.490.31 0.281406.8 1.260.26 0.281415.7 1.580.33 0.251436.8 2.050.43 0.211444.3 1.310.27 0.211450.4 0.210.04 0.09完整細(xì)胞MALDIMRSA 01/270030Data:a0001.1 3 Jul 97 17:50 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1460.90.31 0.06 0.121477.90.41 0.09 0.121502.40.23 0.05 0.121508.60.33 0.07 0.121510.90.44 0.09 0.121513.80.21 0.04 0.091524.50.23 0.05 0.121541.10.48 0.10 0.151546.40.15 0.03 0.091555.30.12 0.03 0.091567.30.21 0.04 0.091571.41.26 0.26 0.251579.61.55 0.32 0.251588.72.51 0.52 0.431644.60.39 0.08 0.121662.30.33 0.07 0.121688.20.91 0.19 0.181723.30.25 0.05 0.121739.10.33 0.07 0.121755.30.48 0.10 0.151767.60.21 0.04 0.091772.80.70 0.15 0.181785.10.37 0.08 0.151795.90.27 0.06 0.091840.70.15 0.03 0.091851.31.35 0.28 0.251863.90.21 0.04 0.091866.80.52 0.11 0.181893.80.81 0.17 0.251903.30.62 0.13 0.121991.80.21 0.04 0.091999.40.21 0.04 0.092060.30.54 0.11 0.182068.50.23 0.05 0.122100.90.35 0.07 0.122107.00.77 0.16 0.182116.50.60 0.12 0.212141.80.39 0.08 0.152171.30.15 0.03 0.092232.10.21 0.04 0.092235.20.21 0.04 0.092245.90.23 0.05 0.092272.90.21 0.04 0.092289.20.23 0.05 0.122308.20.25 0.05 0.122318.20.64 0.13 0.152323.70.29 0.06 0.122336.90.48 0.10 0.152362.20.23 0.05 0.122403.20.31 0.06 0.122422.80.54 0.11 0.182510.10.12 0.03 0.092576.40.23 0.05 0.122584.10.73 0.15 0.152600.00.21 0.04 0.092607.70.31 0.06 0.122660.60.23 0.05 0.09完整細(xì)胞MALDIMRSA 01/270030Data:a0001.1 3Jul 97 17:50 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2688.00.21 0.04 0.092713.10.25 0.05 0.122970.70.62 0.13 0.153054.80.77 0.16 0.153221.10.50 0.10 0.153289.10.12 0.03 0.093440.50.44 0.09 0.153449.40.15 0.03 0.093512.50.39 0.08 0.125025.40.21 0.04 0.09完整細(xì)胞MALDIMRSA 02/270238Data:a0002.3 3 Jul 97 17:53 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:70,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志617.7 1.34 0.36 0.12659.0 0.78 0.21 0.09669.0 0.33 0.09 0.09675.1 52.34 13.94 1.56687.7 1.45 0.39 0.12691.2 100.00 26.63 2.70695.9 1.23 0.33 0.12707.2 92.97 24.75 2.05713.2 2.12 0.56 0.15715.8 0.67 0.18 0.09724.7 36.05 9.60 0.77808.6 0.67 0.18 0.09881.0 0.67 0.18 0.09899.0 7.92 2.11 0.28902.4 15.62 4.16 0.52907.6 0.67 0.18 0.09913.3 3.12 0.83 0.15919.3 16.41 4.37 0.52937.1 14.29 3.80 0.40952.0 4.58 1.22 0.181131.07.25 1.93 0.311133.80.78 0.21 0.091147.63.91 1.04 0.211322.61.34 0.36 0.121328.50.78 0.21 0.121344.72.12 0.56 0.151358.63.12 0.83 0.151388.41.23 0.33 0.121405.90.67 0.18 0.091730.81.12 0.30 0.09完整細(xì)胞MALDI艱難梭菌NCTC 11204Data:diff0032.12 18 Jun 97 15:11 Cal:test 25 Apr 97 11:31Kratos Kompact MALDI 2 V5.2.1:-Linear High Power:90,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV)標(biāo)志529.015.84 3.89 44.21 U541.93.93 0.97 12.10 U545.20.31 0.08 1.72 U546.80.45 0.11 2.11 U550.50.48 0.12 1.81 U568.91.46 0.36 4.38585.20.95 0.23 2.63 U597.71.34 0.33 3.89 U613.71.60 0.39 2.63629.520.23 4.97 30.58643.45.83 1.43 10.69655.99.17 2.25 16.54 U661.50.34 0.08 1.50 U673.5100.00 24.59 152.33695.717.37 4.27 39.74712.14.01 0.99 9.22738.00.83 0.20 1.75766.80.86 0.21 2.30787.752.84 12.99 98.63 U811.51.88 0.46 3.80826.40.90 0.22 1.87838.71.04 0.26 2.45853.010.98 2.70 20.68867.73.31 0.81 6.74 U881.13.17 0.78 7.78897.591.96 22.61 127.14 U920.929.54 7.26 61.03937.37.40 1.82 16.76 U942.50.90 0.22 2.18 U962.11.36 0.33 2.081013.2 0.82 0.20 1.56 U1077.1 1.98 0.49 3.621091.4 1.19 0.29 2.111106.5 1.04 0.26 1.961122.9 8.76 2.15 15.23 U1243.6 0.39 0.10 1.591347.1 1.57 0.39 2.88 U1403.6 0.72 0.18 2.02 U完整細(xì)胞MALDI艱難梭菌NCTC 11206Data:diff0033.13 18 Jun 97 15:12 Cal:test 25 Apr 97 11:31Kratos Kompact MALDI 2 V5.2.1:-Linear High Power:90,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志529.08.35 2.35 20.50541.95.82 1.64 17.19553.21.57 0.44 2.73 U569.11.89 0.53 6.16585.21.19 0.33 2.57 U597.41.09 0.31 3.00 U611.40.43 0.12 1.78 U613.30.78 0.22 1.65 U629.325.04 7.05 33.18 U643.46.81 1.92 9.83655.710.08 2.84 17.80673.2100.00 28.18 138.30 U695.523.15 6.52 49.20711.80.79 0.22 2.05787.733.01 9.30 55.09803.48.09 2.28 16.12 U853.08.47 2.39 14.49866.81.76 0.50 3.68880.52.42 0.68 5.33896.974.00 20.85 97.27920 630.05 8.47 56.77937.00.71 0.20 1.97 U1077 4 1.61 0.45 2.971122.3 6.79 1.91 11.641347.8 0.99 0.28 2.21完整細(xì)胞MALDI艱難梭菌PERFData:diff0037.17 18 Jun 97 15:19 Cal:test 25 Apr 97 11:31Kratos Kompact MALDI 2 V5.2.1:-Linear High Power:95,tDE@ 1000(bin 56)質(zhì)量面積百分比 總百分比 峰值(mV) 標(biāo)志529.2 8.64 2.52 15.32551.4 1.10 0.32 1.19 U569.3 1.93 0.56 3.68585.7 1.68 0.49 1.93598.1 1.15 0.34 1.41611.9 0.61 0.18 1.26 U613.5 0.47 0.14 1.23 U627.9 6.35 1.86 14.15 U629.8 11.47 3.35 17.13 U643.9 5.23 1.53 6.10655.9 6.53 1.91 7.54674.0 92.77 27.10 99.30696.0 14.97 4.37 22.15712.1 0.84 0.25 1.01735.7 0.47 0.14 0.98 U738.3 0.56 0.16 1.07 U788.2 16.91 4.94 20.77810.9 0.84 0.25 1.13838.4 0.97 0.28 1.35853.2 12.49 3.65 14.71867.1 3.01 0.88 4.29881.1 3.79 1.11 4.99897.5 100.00 29.22 97.15921.1 26.23 7.66 37.68937.3 1.58 0.46 2.14 U961.2 2.24 0.65 2.701078.43.40 0.99 3.981091.41.00 0.29 1.381105.51.25 0.36 1.561122.611.95 3.49 13.051347.41.87 0.55 3.12 U完整細(xì)胞MALDI艱難梭菌TETANIData:diff0039.19 18 Jun 97 15:22 Cal:test 25 Apr 97 11:31Kratos Kompact MALDI 2 V5.2.1:-Linear High Power:95,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志513.21.37 0.38 3.71 U529.27.66 2.10 19.88 U542.10.34 0.09 1.41 U547.40.48 0.13 1.44 U551.41.53 0.42 1.75 U569.32.19 0.60 5.58 U585.52.06 0.56 3.80 U597.92.21 0.61 3.74629.524.24 6.65 32.02643.95.57 1.53 9.50656.29.64 2.65 14.83673.7100.00 27.44 141.70696.024.28 6.66 48.71712.11.62 0.44 3.83738.60.94 0.26 1.75788.223.37 6.41 39.19853.213.08 3.59 22.86867.72.99 0.82 5.91881.43.71 1.02 6.86897.784.60 23.21 115.41921.132.93 9.04 61.70937.91.96 0.54 4.44 U943.70.69 0.19 1.84 U1077.7 3.22 0.88 6.281092.7 0.63 0.17 1.471106.2 0.84 0.23 1.781123 2 10.41 2.86 17.651303.7 0.63 0.17 1.691348.5 1.25 0.34 2.30完整細(xì)胞MALDIMyco Cardiff 1/0036cData:CAR0002.2 30 May 97 17:06 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 3819(bin 109)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志792.6 0.80 0.05 0.31838.0 0.92 0.06 0.34850.1 1.78 0.11 0.67 U863.1 24.18 1.44 6.00 U877.6 4.43 0.26 1.38 U883.8 6.54 0.39 1.69 U896.5 4.01 0.24 1.16904.4 3.32 0.20 1.32 U912.4 12.09 0.72 3.16 U922.7 4.80 0.29 1.26 U938.9 2.23 0.13 0.43 U950.2 21.29 1.27 4.50 U964.6 3.03 0.18 0.80 U978.4 45.32 2.71 11.46 U993.0 9.20 0.55 2.51 U1006.4100.00 5.97 24.97 U1020.95.73 0.34 1.90 U1034.836.44 2.18 11.46 U1040.034.03 2.03 10.75 U1051.08.36 0.50 1.84 U1067.658.51 3.49 13.20 U1080.08.21 0.49 1.93 U1094.729.85 1.78 7.44 U1108.58.80 0.53 2.18 U1122.112.20 0.73 3.46 U1136.413.15 0.79 2.45 U1149.85.72 0.34 1.75 U1166.610.02 0.60 2.11 U1180.24.50 0.27 1.16 U1195.27.04 0.42 1.16 U1205.04.06 0.24 0.89 U1218.56.06 0.36 1.59 U1231.77.10 0.42 1.59 U1245.78.62 0.51 2.27 U1259.813.71 0.82 2.91 U1277.312.19 0.73 2.82 U1288.510.42 0.62 2.54 U1304.134.21 2.04 5.94 U1318.513.90 0.83 3.65 U1332.613.05 0.78 2.91 U1346.518.15 1.08 5.02 U1361.115.28 0.91 3.80 U1373.77.52 0.45 1.96 U1388.410.30 0.62 2.21 U1404.73.75 0.22 1.38 U1416.86.92 0.41 1.84 U1425.33.95 0.24 1.38 U1432.54.51 0.27 1.10 U1445.88.30 0.50 1.53 U1458.04.88 0.29 1.16 U1475.815.08 0.90 3.52 U1493.616.57 0.99 1.87 U1532.320.83 1.24 1.50 U1555.75.54 0.33 1.38 U1573.217.27 1.03 3.40 U1591.314.10 0.84 3.74 U1598.119.52 1.17 2.70 U完整細(xì)胞MALDIMyco Cardiff 1/0036cData:CAR0002.2 30 May 9717:06 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI2 V5.2.1:+Linear High Power:75,tDE @ 3819(bin 109)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志1626.24.31 0.26 1.44 U1646.516.75 1.00 2.54 U1671.98.90 0.53 1.62 U1681.620.03 1.20 3.49 U1703.815.34 0.92 3.40 U1715.91.37 0.08 0.74 U1732.011.64 0.70 2.76 U1741.112.82 0.77 3.03 U1755.316.73 1.00 5.09 U1760.913.23 0.79 3.71 U1773.22.20 0.13 0.83 U1787.15.27 0.32 1.26 U1802.05.91 0.35 1.47 U1817.798.66 5.89 18.72 U1839.910.54 0.63 2.57 U1866.87.46 0.45 1.19 U1880.32.03 0.12 0.58 U1889.710.39 0.62 2.70 U1907.53.85 0.23 1.19 U1917.07.30 0.44 1.72 U1929.06.41 0.38 1.78 U1935.23.23 0.19 1.10 U1949.85.92 0.35 1.19 U1963.25.03 0.30 1.26 U1973 730.14 1.80 5.06 U1988.923.53 1.41 5.33 U2004.118.22 1.09 3.92 U2018.918.35 1.10 3.68 U2031.33.02 0.18 1.23 U2044.56.76 0.40 1.78 U2063.85.01 0.30 0.92 U2080.17.17 0.43 1.65 U2091.46.06 0.36 1.29 U2104.82.85 0.17 1.16 U2110.94.51 0.27 1.50 U2120.97.32 0.44 1.87 U2133.17.95 0.47 1.72 U2153.77.88 0.47 2.18 U2160.36.64 0.40 1.65 U2171.33.65 0.22 1.23 U2182.74.34 0.26 1.19 U2201.311.27 0.67 2.24 U2214.211.61 0.69 2.02 U2234.811.92 0.71 2.94 U2254.519.55 1.17 4.60 U2271.615.04 0.90 3.46 U2286.94.88 0.29 1.32 U2305.026.39 1.58 6.65 U2319.114.10 0.84 2.82 U2336.54.34 0.26 1.35 U2350.73.33 0.20 0.89 U2369.110.27 0.61 1.50 U2417.69.35 0.56 1.19 U2433.014.51 0.87 3.00 U2443.86.35 0.38 1.47 U2461.122.88 1.37 4.53 U2488.82.82 0.17 0.67 U完整細(xì)胞MALDIMyco Cardiff 1/0036cData:CAR0002.2 30 May 97 17:06 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 3819(bin 109)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志2507.37.93 0.47 1.59 U2522.08.49 0.51 1.84 U2539.111.36 0.68 1.56 U2579.87.17 0.43 1.29 U2604.89.66 0.58 1.53 U2620.85.57 0.33 1.19 U2644.12.89 0.17 0.98 U2657.211.59 0.69 2.02 U2676.37.07 0.42 1.01 U2710.625.00 1.49 3.86 U2724.44.58 0.27 1.50 U2769.09.57 0.57 1.72 U2789.54.88 0.29 1.04 U2805.015.85 0.95 2.76 U2864.410.04 0.60 1.472900.52.35 0.14 0.492948.515.82 0.95 2.302999.18.21 0.49 1.233064.24.49 0.27 0.403111.02.87 0.17 0.613247.54.00 0.24 0.61 U3177.33.42 0.20 0.55 U3207.72.22 0.13 0.583224.33.25 0.19 0.523250.70.98 0.06 0.253340.34.66 0.28 0.463378.10.74 0.04 0.287634.529.92 1.79 2.14完整細(xì)胞MALDIMyco Cardiff 31/0352cData:CAR0082.2 3 Jun 97 16:27 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志881.3 1.06 0.11 0.55913.0 2.46 0.25 1.691006.13.11 0.31 1.991035.41.25 0.13 0.641065.52.28 0.23 0.58 U1072.03.14 0.32 1.47 U1087.22.48 0.25 1.23 U1103.81.87 0.19 0.671137.72.11 0.21 0.52 U1167.22.35 0.24 1.011233.72.86 0.29 1.72 U1254.72.31 0.23 1.44 U1260.85.44 0.55 3.09 U1268.51.85 0.19 1.41 U1276.611.66 1.17 6.62 U1290.55.08 0.51 2.73 U1303.157.08 5.73 27.42 U1318.927.75 2.79 16.79 U1330.930.54 3.07 17.92 U1345.840.66 4.08 23.901361.418.86 1.89 10.51 U1373.317.10 1.72 10.42 U1389.16.43 0.65 4.201401.91.58 0.16 1.071418.61.93 0.19 1.01 U1426.43.03 0.30 1.16 U1449.01.75 0.18 0.95 U1479.43.75 0.38 0.74 U1488.13.24 0.33 1.38 U1496.62.00 0.20 1.41 U1507.52.48 0.25 1.04 U1514.21.44 0.14 0.89 U1539.74.71 0.47 1.10 U1552.34.02 0.40 0.98 U1573.22.03 0.20 0.70 U1606.44.72 0.47 0.89 U1621.62.86 0.29 0.95 U1637.71.11 0.11 0.86 U1642.61.73 0.17 1.07 U1658.42.01 0.20 1.04 U1665.01.79 0.18 0.98 U1677.72.37 0.24 1.13 U1696.05.18 0.52 1.38 U1714.71.05 0.11 0.92 U1722.63.32 0.33 2.02 U1739.53.88 0.39 1.53 U1749.42.18 0.22 1.23 U1756.51.56 0.16 1.16 U1765.63.86 0.39 1.26 U1781.12.44 0.25 1.50 U1790.71.62 0.16 1.01 U1809.64.88 0.49 1.87 U1829.43.17 0.32 1.07 U1842.30.91 0.09 0.64 U1854.50.61 0.06 0.64 U1867.63.09 0.31 1.01 U1886.90.62 0.06 0.52 U完整細(xì)胞MALDIMyco Cardiff 31/0352cData:CAR0082.2 3 Jun 97 16:27 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志1895.91.31 0.13 0.92 U1902.91.12 0.11 0.96 U1926.11.62 0.16 1.44 U1931.52.54 0.25 2.05 U1947.317.04 1.71 8.64 U1961.97.84 0.79 4.93 U1974.1100.00 10.04 52.36 U1989.759.98 6.02 32.94 U2002.046.84 4.70 26.07 U2017.262.90 6.32 35.97 U2032.120.67 2.08 13.27 U2044.516.82 1.69 10.94 U2059.97.32 0.74 5.332073.21.73 0.17 1.532088.31.39 0.14 1.042109.12.66 0.27 0.98 U2121.33.56 0.36 1.59 U2152.85.18 0.52 1.62 U2164.26.95 0.70 2.70 U2175.74.13 0.42 1.87 U2192.01.62 0.16 1.19 U2216.94.62 0.46 1.29 U2234.31.47 0.15 0.80 U2243.32.61 0.26 1.62 U2252.24.99 0.50 1.96 U2266.61.88 0.19 1.10 U2278.32.03 0.20 1.29 U2291.01.43 0.14 0.89 U2299.61.43 0.14 1.01 U2307.33.22 0.32 1.19 U2325.11.07 0.11 0.83 U2339.72.68 0.27 1.19 U2354.43.79 0.38 1.38 U2370.05.91 0.59 2.70 U2388.94.53 0.45 1.41 U2416.72.13 0.21 0.86 U2432.16.65 0.67 1.69 U2464.42.95 0.30 1.23 U2479.46.16 0.62 1.72 U2504.04.20 0.42 1.75 U2527.22.68 0.27 1.47 U2538.25.39 0.54 1.53 U2568.34.26 0.43 1.41 U2592.84.20 0.42 1.41 U2618.82.39 0.24 1.10 U2633.92.35 0.24 1.47 U2661.17.83 0.79 2.48 U2704.766.01 6.63 24.20 U2751.21.94 0.20 1.10 U2762.65.71 0.57 1.44 U2795.51.72 0.17 0.80 U2815.02.04 0.20 1.04 U2825.62.13 0.21 1.29 U2849.35.40 0.54 1.62 U2869.53.28 0.33 1.04 U2894.91.56 0.16 0.80 U2919.92.12 0.21 0.83 U完整細(xì)胞MALDIMyco Cardiff 31/0352cData:CAR0082.2 3 Jun 97 16:27 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志2928.61.05 0.11 0.86 U2943.44.14 0.42 1.65 U2967.13.05 0.31 1.23 U2981.51.00 0.10 0.64 U2995 01.86 0.19 0.89 U3018.32.83 0.28 1.35 U3032.90.86 0.09 0.64 U3054.84.50 0.45 0.92 U3092.02.53 0.25 0.86 U3108.93.68 0.37 1.78 U3125.21.38 0.14 0.61 U3148.54.60 0.46 1.65 U3167.71.62 0.16 0.67 U3200.82.17 0.22 0.61 U3237.24.58 0.46 1.26 U3276.62.28 0.23 0.95 U3332.13.02 0.30 1.07 U3362.75.16 0.52 0.98 U3422.216.59 1.67 5.88 U3449.41.63 0.16 0.52 U3490.13.20 0.32 0.743591.41.83 0.18 0.52 U3642.03.64 0.37 0.83 U3709.73.62 0.36 0.58 U3772.72.57 0.26 0.643811.72.13 0.21 0.58 U3871.51.39 0.14 0.52 U3896.93.04 0.31 1.35 U3914.02.60 0.26 1.07 U3933.02.07 0.21 0.83 U3974.61.33 0.13 0.58 U3987.11.75 0.18 0.61 U4859.83.58 0.36 0.77完整細(xì)胞MALDIMyco Cardiff 33/0589cData:CAR0086.6 3 Jun 97 16:37 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志526.80.54 0.04 0.43866.21.89 0.15 1.23882.13.62 0.28 1.81898.52.14 0.17 0.89915.31.18 0.09 0.49940.61.98 0.15 0.89956.11.12 0.09 0.43982.31.35 0.11 0.521008.5 3.87 0.30 0.581020.0 1.59 0.12 0.431056.2 2.95 0.23 0.95 U1072.0 7.08 0.55 2.21 U1088.1 3.06 0.24 1.50 U1094.7 2.11 0.16 0.92 U1104.7 0.92 0.07 0.58 U1111.7 0.88 0.07 0.49 U1122.7 1.80 0.14 0.58 U1136.7 1.69 0.13 0.61 U1153.0 1.45 0.11 0.461166.2 2.77 0.22 0.861193.5 2.50 0.20 0.551212.9 2.98 0.23 0.741228.4 1.70 0.13 1.04 U1233.7 3.06 0.24 1.29 U1255.1 6.02 0.47 1.75 U1261.4 7.57 0.59 3.71 U1268.5 3.15 0.25 1.56 U1277.3 15.32 1.20 4.78 U1290.2 9.59 0.75 3.86 U1295.9 6.04 0.47 3.37 U1304.1 36.71 2.87 14.31 U1319.9 16.58 1.30 6.83 U1331.6 18.41 1.44 7.66 U1347.5 8.59 0.67 3.65 U1360.0 5.72 0.45 2.14 U1375.8 3.06 0.24 1.10 U1390.2 1.99 0.16 0.58 U1401.2 1.43 0.11 0.58 U1418.9 2.09 0.16 0.89 U1426.8 1.15 0.09 0.55 U1442.2 4.20 0.33 1.01 U1451.5 2.85 0.22 0.92 U1466.3 4.94 0.39 1.69 U1477.6 3.23 0.25 1.29 U1487.4 6.21 0.49 1.26 U1506.1 2.02 0.16 0.98 U1511.2 1.44 0.11 0.92 U1522.3 3.24 0.25 1.01 U1535.2 3.73 0.29 1.47 U1554.5 7.65 0.60 2.27 U1570.2 7.55 0.59 1.81 U1582.3 4.24 0.33 1.75 U1597.0 3.59 0.28 1.16 U1612.1 4.07 0.32 1.19 U1625.1 3.76 0.29 1.72 U1637.7 2.89 0.23 1.101653.4 3.32 0.26 1.87完整細(xì)胞MALDIMyco Cardiff 33/0589cData:CAR0086.6 3 Jun 97 16:37 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志1667.35.640.44 2.701680.814.52 1.14 6.801696.015.33 1.20 6.281714.736.25 2.84 14.86 U1729.298.68 7.72 34.93 U1744.257.05 4.46 23.65 U1757.361.17 4.78 26.87 U1771.6100.00 7.82 42.74 U1786.380.92 6.33 34.87 U1800.050.42 3.94 23.19 U1814.436.86 2.88 16.64 U1828.230.88 2.42 14.43 U1842.710.60 0.83 5.271857.02.740.21 1.411871.72.220.17 1.261887.72.160.17 0.74 U1904.63.730.29 1.16 U1914.94.050.32 1.38 U1924.02.460.19 0.95 U1941.15.970.47 1.32 U1961.15.530.43 1.87 U1975.06.850.54 2.18 U1989.711.09 0.87 3.40 U2001.56.430.50 2.27 U2018.95.650.44 2.11 U2032.16.170.48 1.50 U2062.13.430.27 0.98 U2073.73.620.28 1.19 U2088.31.630.13 0.89 U2096.61.640.13 0.86 U2108.34.110.32 1.32 U2119.17.040.55 2.73 U2133.17.930.62 2.48 U2163.88.240.64 1.75 U2174.85.870.46 1.35 U2194.70.770.06 0.58 U2204.93.960.31 0.95 U2223.62.810.22 0.83 U2234.81.960.15 0.89 U2245.54.070.32 1.07 U2259.03.260.25 1.44 U2269.81.260.10 0.77 U2285.13.200.25 0.95 U2291.41.240.10 0.80 U2299.62.100.16 1.10 U2306.92.320.18 1.38 U2313.72.440.19 0.95 U2328.32.380.19 0.89 U2342.44.140.32 1.19 U2361.23.870.30 1.59 U2371.89.830.77 2.88 U2388.93.200.25 1.13 U2399.51.400.11 0.83 U2419.03.380.26 0.80 U2433.92.720.21 1.10 U2461.65.960.47 1.19 U2479.43.270.26 1.29 U完整細(xì)胞MALDIMyco Cardiff 33/0589cData:CAR0086.6 3 Jun 97 16:37 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV) 標(biāo)志2492.22.89 0.23 0.98 U2506.86.39 0.50 1.81 U2520.12.61 0.20 1.10 U2538.65.71 0.45 1.59 U2550.66.99 0.55 2.11 U2565.96.46 0.50 1.90 U2577 94.69 0.37 2.02 U2593.76.97 0.55 1.96 U2607.73.61 0.28 1.44 U2619.84.81 0.38 1.26 U2651.93.87 0.30 0.89 U2664.52.67 0.21 1.16 U2689.03.03 0.24 0.77 U2706.215.50 1.21 5.67 U2719.57.12 0.56 2.02 U2743.73.91 0.31 1.23 U2768.59.32 0.73 1.32 U2918.05.71 0.45 1.50 U2838.22.36 0.18 0.64 U2855.83.89 0.30 0.98 U2875.13.68 0.29 0.95 U2904.04.13 0.32 0.922932.65.51 0.43 1.41 U2964.06.64 0.52 1.69 U2982.55.51 0.43 1.53 U3002.29.77 0.76 2.18 U3016.23.11 0.24 1.41 U3031.87.93 0.62 2.45 U3048.05.71 0.45 1.96 U3060.03.94 0.31 1.78 U3074.73.00 0.23 1.29 U3088.33.96 0.31 1.65 U3103.12.11 0.17 1.07 U3149.64.22 0.33 0.743193.32.36 0.18 0.67 U3239.94.80 0.38 0.89 U3261.52.81 0.22 0.52 U3311.45.77 0.45 0.74 U3389.73.50 0.27 0.58 U3400.11.91 0.15 0.74 U3424.56.95 0.54 1.56 U3455.51.48 0.12 0.64 U3475.63.00 0.23 0.89 U3501.85.20 0.41 0.80 U3527.61.54 0.12 0.58 U3552.93.18 0.25 0.433700.52.65 0.21 0.553766.31.61 0.13 0.403801.21.10 0.09 0.493875.13.12 0.24 1.07 U3897.53.43 0.27 0.89 U3918.23.48 0.27 0.77 U完整細(xì)胞MALDIMyco Cardiff 63/0545cData:CAR0146.6 4 Jun 97 14:12 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比 峰值(mV) 標(biāo)志646.7 4.03 0.37 3.43654.6 0.85 0.08 0.86670.5 3.25 0.30 2.45686.7 1.40 0.13 0.67710.5 1.37 0.12 0.37733.6 3.15 0.29 1.50751.4 1.30 0.12 0.55776.5 4.83 0.44 2.79792.9 3.97 0.36 2.24810.3 3.97 0.36 2.11 U817.3 1.38 0.13 0.77 U826.8 1.15 0.10 0.55 U836.4 2.39 0.22 1.41 U844.0 0.41 0.04 0.40852.6 2.16 0.20 1.16 U860.3 3.65 0.33 2.79 U866.2 5.41 0.49 3.19 U875.9 3.68 0.34 2.11 U882.1 12.29 1.12 6.16 U898.2 13.01 1.19 5.73 U915.0 9.23 0.84 2.94932.2 1.49 0.14 0.92 U940.6 5.60 0.51 2.21 U956.9 4.35 0.40 2.18973.1 4.40 0.40 1.26 U990.0 2.90 0.26 0.95 U1001.6 5.33 0.49 1.35 U1018.8 2.88 0.26 1.50 U1026.0 1.58 0.14 0.77 U1034.8 1.89 0.17 0.83 U1044.9 2.08 0.19 0.89 U1057.8 2.26 0.21 1.07 U1072.3 15.17 1.38 5.27 U1088.4 15.21 1.39 5.82 U1104.4 8.50 0.78 3.03 U1128.7 6.32 0.58 1.59 U1142.5 0.98 0.09 0.64 U1146.9 2.69 0.25 0.98 U1165.6 1.38 0.13 0.98 U1170.4 1.94 0.18 1.04 U1184.4 2.37 0.22 1.07 U1191.6 1.27 0.12 0.74 U1199.1 0.66 0.06 0.58 U1206.6 1.40 0.13 0.86 U1215.5 2.61 0.24 1.07 U1228.7 1.76 0.16 1.16 U1234.4 2.55 0.23 1.50 U1249.7 1.84 0.17 1.38 U1254.7 3.64 0.33 2.24 U1261.8 9.57 0.87 5.06 U1268.8 1.17 0.11 1.29 U1277.3 19.25 1.76 8.43 U1290.5 22.02 2.01 7.11 U1304.5 52.42 4.79 24.05 U1319.9 36.04 3.29 17.03 U1332.3 24.24 2.21 12.16 U1347.9 16.71 1.52 8.98 U完整細(xì)胞MALDIMyco Cardiff 63/0545cData:CAR0146.6 4 Jun 97 14:12 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志1360.45.95 0.54 2.79 U1376.56.73 0.61 2.30 U1406.82.65 0.24 0.98 U1426.14.18 0.38 1.07 U1435.42.06 0.19 1.16 U1442.91.28 0.12 0.95 U1451.53.78 0.34 1.84 U1461.33.90 0.36 1.44 U1477.65.59 0.51 1.38 U1489.61.65 0.15 1.07 U1496.92.68 0.24 1.62 U1507.55.24 0.48 1.47 U1525.29.16 0.84 1.87 U1558.33.47 0.32 1.10 U1572.96.28 0.57 1.90 U1587.94.13 0.38 1.35 U1598.12.75 0.25 1.04 U1612.15.71 0.52 2.24 U1625.82.27 0.21 1.41 U1640.02.08 0.19 0.77 U1653.83.96 0.36 2.08 U1667.73.65 0.33 2.451681.611.57 1.06 6.221696.415.52 1.42 6.991714.724.69 2.25 12.41 U1729.2100.00 9.13 39.61 U1744.668.43 6.25 30.85 U1757.738.83 3.55 19.85 U1772.077.34 7.06 38.02 U1786.765.16 5.95 32.41 U1800.431.38 2.86 17.10 U1814.821.67 1.98 12.011829.418.39 1.68 9.991843.27.08 0.65 4.531857.80.80 0.07 0.49 U1871.31.55 0.14 1.13 U1888.13.46 0.32 1.07 U1900.02.64 0.24 1.26 U1907.91.46 0.13 1.04 U1917.41.22 0.11 0.83 U1924.42.07 0.19 0.98 U1936.51.74 0.16 0.98 U1945.22.36 0.22 1.23 U1954.01.41 0.13 0.67 U1965.72.19 0.20 1.19 U1986.76.56 0.60 1.41 U2004.52.59 0.24 1.29 U2018.53.81 0.35 1.01 U2041.92.02 0.18 0.67 U2057.32.84 0.26 1.23 U2080.64.89 0.45 1.13 U2101.33.51 0.32 0.80 U2118.71.93 0.18 0.70 U2141.85.03 0.46 0.89 U2166.94.49 0.41 1.13 U2186.31.41 0.13 0.55 U2204.02.51 0.23 0.98 U完整細(xì)胞MALDIMyco Cardiff 63/0545cData:CAR0146.6 4 Jun 97 14:12 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:75,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比峰值(mV)標(biāo)志2218.23.01 0.27 1.10 U2231.61.93 0.18 0.77 U2253.12.55 0.23 0.80 U2273.42.08 0.19 0.89 U2287.40.95 0.09 0.55 U2299.63.37 0.31 0.92 U2332.83.52 0.32 0.70 U2347.91.63 0.15 0.86 U2370.03.27 0.30 0.86 U2391.21.02 0.09 0.55 U2419.02.63 0.24 0.70 U2432.52.47 0.23 0.74 U2455.92.65 0.24 0.55 U2486.02.48 0.23 0.74 U2495.51.56 0.14 0.67 U2520.61.64 0.15 0.46 U2537.22.22 0.20 0.67 U2576.42.61 0.24 0.61 U2591.30.79 0.07 0.43 U2606.81.79 0.16 0.64 U2637.34.91 0.45 0.46 U2707.25.29 0.48 1.84 U2723.02.86 0.26 0.89 U2758.62.45 0.22 0.462816.02.41 0.22 0.70 U2836.12.00 0.18 0.58 U2876.11.80 0.16 0.55 U2916.82.17 0.20 0.55 U2948.52.41 0.22 0.64 U2966.61.26 0.12 0.40 U2999.13.35 0.31 0.493056.91.77 0.16 0.433131.64.02 0.37 0.40 U3177.81.35 0.12 0.37 U3266.93.34 0.30 0.553424.53.43 0.31 0.463525.91.33 0.12 0.403663.71.51 0.14 0.373849.80.90 0.08 0.433915.21.64 0.15 0.40完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志502.1 0.220.03 0.09507.9 0.340.04 0.12518.8 0.430.06 0.12524.8 26.09 3.36 2.30542.7 100.00 12.86 9.07 U552.9 13.82 1.78 0.80 U565.0 14.18 1.82 1.23580.9 10.34 1.33 0.67587.3 2.920.38 0.31604.1 4.120.53 0.34619.1 0.740.09 0.12635.7 0.650.08 0.12653.2 1.380.18 0.18657.3 8.981.16 0.77665.6 14.43 1.86 1.38673.4 15.91 2.05 1.26688.2 10.09 1.30 0.80699.9 0.710.09 0.12701.7 0.220.03 0.09713.7 52.09 6.70 4.14729.2 16.86 2.17 1.07 U735.1 27.35 3.52 2.11 U740.3 5.780.74 0.49 U750.3 36.86 4.74 1.16771.7 0.580.08 0.15783.1 10.80 1.39 0.37810.3 0.180.02 0.09820.8 0.340.04 0.12896.8 0.180.02 0.091016.30.770.10 0.181177.20.460.06 0.121366.00.220.03 0.091603.00.340.04 0.091876.60.490.06 0.121942.73.660.47 0.461964.58.651.11 1.231980.41.080.14 0.211987.21.260.16 0.212009.60.830.11 0.152074.17.420.98 0.862096.113.78 1.77 1.532112.24.740.61 0.612118.30.860.11 0.152128.70.460.06 0.092134.41.230.16 0.152176.60.370.05 0.122213.81.820.23 0.252258.50.520.07 0.122313.70.310.04 0.092321.40.800.10 0.122349.30.460.06 0.122372.70.830.11 0.182388.00.580.08 0.122442.80.950.12 0.152446.61.110.14 0.182470.00.680.09 0.152476.11.720.22 0.18完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志2504.40.52 0.07 0.122522.50.22 0.03 0.092533.40.46 0.06 0.122543.42.80 0.36 0.182552.50.77 0.10 0.122564.92.00 0.26 0.182575.00.95 0.12 0.122585.60.58 0.08 0.122593.31.14 0.15 0.122601.41.91 0.25 0.182627.10.89 0.11 0.122639.77.75 1.00 0.522652.80.31 0.04 0.092660.10.58 0.08 0.122678.72.43 0.31 0.182685.64.00 0.51 0.282696.40.77 0.10 0.122702.33.32 0.43 0.212720.00.68 0.09 0.122740.80.18 0.02 0.092746.70.71 0.09 0.122757.61.29 0.17 0.182771.52.52 0.32 0.212779.50.18 0.02 0.092784.50.31 0.04 0.092790.00.86 0.11 0.122794.51.14 0.15 0.122808.02.28 0.29 0.212829.10.83 0.11 0.152833.61.20 0.15 0.182848.73.63 0.47 0.282858.910.80 1.39 0.372900.55.42 0.70 0.252918.83.66 0.47 0.312928.61.14 0.15 0.152942.91.23 0.16 0.182951.11.17 0.15 0.152958.80.77 0.10 0.122962.90.31 0.04 0.092972.72.28 0.29 0.152984.61.88 0.24 0.252999.60.74 0.09 0.123005.80.31 0.04 0.093011.50.74 0.09 0.153019.31.45 0.19 0.123033.90.58 0.08 0.123037.50.98 0.13 0.153047.51.42 0.18 0.183072.62.74 0.35 0.183087.81.08 0.14 0.093096.20.83 0.11 0.123101.50.46 0.06 0.123109.90.31 0.04 0.093115.20.34 0.04 0.093120.51.11 0.14 0.183142.25.14 0.66 0.213146.90.22 0.03 0.09完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志3152.20.31 0.04 0.093162.31.02 0.13 0.153169.30.74 0.09 0.123182.61.69 0.22 0.153193.81.72 0.22 0.123201.80.34 0.04 0.123209.32.98 0.38 0.153230.30.58 0.08 0.123250.21.94 0.25 0.183279.95.17 0.66 0.253291.30.65 0.08 0.093311.40.18 0.02 0.093317.90.46 0.06 0.123325.60.40 0.05 0.093332.61.02 0.13 0.153340.30.58 0.08 0.123346.90.62 0.08 0.123356.21.91 0.25 0.183382.04.68 0.60 0.343400.12.49 0.32 0.183412.81.02 0.13 0.153418.40.43 0.06 0.093423.31.14 0.15 0.093439.40.83 0.11 0.153465.00.34 0.04 0.093474.45.48 0.70 0.253491.25.78 0.74 0.283511.33.94 0.51 0.213523.11.38 0.18 0.183534.47.08 0.91 0.373551.22.77 0.36 0.183563.71.97 0.25 0.183571.63.45 0.44 0.253596.50.18 0.02 0.093605.00.62 0.08 0.123615.80.92 0.12 0.153626.60.74 0.09 0.123631.71.02 0.13 0.123641.40.65 0.08 0.093650.00.65 0.08 0.123672.95.78 0.74 0.313686.72.06 0.27 0.283699.30.74 0.09 0.153710.21.85 0.24 0.253733.31.05 0.13 0.153743.71.94 0.25 0.253762.30.58 0.08 0.123769.81.32 0.17 0.153780.32.03 0.26 0.213798.92.68 0.34 0.153836.31.94 0.25 0.213843.90.58 0.08 0.123858.61.17 0.15 0.183867.41.82 0.23 0.183896.91.35 0.17 0.153922.32.31 0.30 0.153935.40.77 0.10 0.12完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志3941.31.11 0.14 0.153950.80.83 0.11 0.153956.11.75 0.23 0.154010.55.45 0.70 0.374023.73.75 0.48 0.184050.72.71 0.35 0.254071.23.11 0.40 0.154093.63.45 0.44 0.254106.30.92 0.12 0.154119.63.35 0.43 0.254153.12.09 0.27 0.124166.51.69 0.22 0.184181.85.57 0.72 0.254205.71.23 0.16 0.184220.40.43 0.06 0.094346.92.80 0.36 0.124258.01.54 0.20 0.214300.01.75 0.23 0.154314.90.55 0.07 0.094324.92.09 0.27 0.154352.30.83 0.11 0.154371.01.35 0.17 0.154386.00.89 0.11 0.124435.70.98 0.13 0.124468.50.80 0.10 0.124510.91.32 0.17 0.184564.50.55 0.07 0.094573.40.31 0.04 0.094606.71.54 0.20 0.154630.51.02 0.13 0.154647.90.31 0.04 0.094695.77.82 1.01 0.284717.86.06 0.78 0.314734.10.92 0.12 0.154741.21.08 0.14 0.154769.90.68 0.09 0.094781.00.40 0.05 0.094790.22.86 0.37 0.214812.50.77 0.10 0.124833.55.05 0.65 0.344854.60.62 0.08 0.124879.62.52 0.32 0.254904.80.43 0.06 0.094963.90.34 0.04 0.124977.91.26 0.16 0.155015.30.55 0.07 0.095022.70.71 0.09 0.125095.40.40 0.05 0.095103.50.31 0.04 0.095148.20.46 0.06 0.125383.60.31 0.04 0.095484.00.31 0.04 0.095545.114.98 1.93 0.745568.38.28 1.06 0.615584.62.52 0.32 0.185607.90.77 0.10 0.095617.83.26 0.42 0.25完整細(xì)胞MALDIMeningo 1/M96255506Data:a0002.2 3 Jul 97 14:39 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:60,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV) 標(biāo)志5631.31.48 0.19 0.185683.22.46 0.32 0.185701.81.72 0.22 0.155721.80.43 0.06 0.096013.86.28 0.81 0.376033.62.55 0.33 0.216069.611.02 1.42 0.556091.03.75 0.48 0.256151.01.02 0.13 0.12完整細(xì)胞MALDIMeningo 5/M96255510Data:a0009.9 3 Jul 97 15:03 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:58,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志500.216.10 1.65 5.94 U509.30.960.10 0.52 U511.11.680.17 0.77 U516.0100.00 10.24 26.50 U520.16.500.67 2.51 U525.716.29 1.67 4.93 U532.086.19 8.82 21.23 U543.966.76 6.84 16.73 U551.24.520.46 1.87 U553.25.570.57 2.24 U558.11.440.15 0.83563.93.490.36 1.44 U566.110.84 1.11 3.09 U575.40.840.09 0.49582.017.18 1.76 4.99587.90.730.07 0.34598.30.590.06 0.34604.310.71 1.10 2.73620.714.90 1.53 2.76633.81.870.19 0.92636.10.830.09 0.31644.85.860.60 1.04652.90.330.03 0.25659.013.30 1.36 2.05 U666.822.73 2.33 5.85 U674.624.07 2.46 5.76690.269.23 7.09 13.51706.427.36 2.80 5.06 U715.320.15 2.06 4.60 U731.368.65 7.03 10.72746.58.860.91 1.35 U750.324.51 2.51 7.66 U753.224.65 2.52 6.16 U757.15.850.60 2.42 U762.019.36 1.98 3.83 U769.415.50 1.59 4.78 U773.017.49 1.79 3.71 U784.920.78 2.13 3.03801.214.75 1.51 2.51810.83.130.32 0.64825.71.560.16 0.58 U828.44.130.42 0.89 U836.40.750.08 0.31840.50.670.07 0.28855.13.760.38 0.61865.32.610.27 0.43880.42.940.30 0.64897.03.750.38 0.86 U902.42.580.26 0.83 U907.30.610.06 0.31913.61.770.18 0.52 U920.12.190.22 0.61 U930.51.980.20 0.37936.30.520.05 0.28942.96.940.71 1.41956.15.840.60 1.59967.51.420.15 0.34完整細(xì)胞MALDIMeningo 5/M96255510Data:a0009.9 3 Jul 97 15:03 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:58,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志985.8 2.36 0.24 0.52989.1 0.46 0.05 0.31995.1 1.51 0.15 0.311003.10.90 0.09 0.281018.25.30 0.54 0.701031.50.90 0.09 0.371043.12.74 0.28 0.49 U1047.90.97 0.10 0.40 U1056.54.84 0.50 0.741072.90.56 0.06 0.251077.21.20 0.12 0.281091.31.89 0.19 0.401101.31.44 0.15 0.491112.91.93 0.20 0.401126.83.91 0.40 0.771142.51.39 0.14 0.311155.911.72 1.20 2.701171.11.89 0.19 0.281178.27.26 0.74 1.651194.26.23 0.64 2.051202.00.53 0.05 0.341207.91.00 0.10 0.431215.83.36 0.34 0.701226.81.51 0.15 0.43 U1231.41.61 0.16 0.52 U1237.01.48 0.15 0.341245.40.99 0.10 0.431258.80.91 0.09 0.281274.61.13 0.12 0.341287.46.62 0.68 1.931295.91.14 0.12 0.281303.10.47 0.05 0.251309.91.08 0.11 0.431325.78.12 0.83 1.041342.00.50 0.05 0.281351.32.27 0.23 0.311367.01.31 0.13 0.341370.91.58 0.16 0.311386.71.11 0.11 0.431409.01.81 0.18 0.311431.41.15 0.12 0.281444.02.98 0.31 0.521456.61.13 0.12 0.401475.41.26 0.13 0.401492.93.55 0.36 0.491500.20.74 0.08 0.281507.52.33 0.24 0.311534.80.56 0.06 0.251556.84.03 0.41 0.521605.32.06 0.21 0.371626.62.13 0.22 0.521642.61.44 0.15 0.401665.01.41 0.14 0.311687.03.14 0.32 0.671726.50.63 0.06 0.281749.00.73 0.07 0.281780.80.57 0.06 0.28完整細(xì)胞MALDIMeningo 5/M96255510Data:a0009.9 3 Jul 97 15:03 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:58,tDE @ L000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志1787.51.47 0.15 0.251843.20.76 0.08 0.281857.42.60 0.27 0.371899.61.10 0.11 0.281937.30.48 0.05 0.251945.61.87 0.19 0.611953.21.29 0.13 0.341967.02.20 0.23 0.491983.02.46 0.25 0.83 U1990.11.61 0.16 0.61 U2027.41.41 0.14 0.282045.31.02 0.10 0.252077.13.20 0.33 0.432114.83.49 0.36 0.492153.71.04 0.11 0.282197.80.47 0.05 0.252228.51.29 0.13 0.282238.30.60 0.06 0.282315.50.39 0.04 0.252341.50.77 0.08 0.252376.00.94 0.10 0.28完整細(xì)胞MALDIMeningo 10/M97251540Data:a0019.19 3 Jul 97 15:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量面積百分比 總百分比 峰值(mV)標(biāo)志512.3 1.58 0.28 0.67516.4 0.59 0.11 0.46520.7 0.53 0.09 0.46522.9 0.46 0.08 0.43 U526.3 22.76 4.05 6.95 U541.0 5.96 1.06 2.45 U544.5 100.00 17.80 36.34 U552.9 14.75 2.62 3.62 U567.0 12.62 2.25 6.00582.9 22.52 4.01 8.64 U588.9 3.49 0.62 1.59 U605.5 11.51 2.05 5.64621.4 6.45 1.15 2.54 U627.6 4.14 0.74 1.75 U643.3 3.72 0.66 1.10659.5 5.81 1.03 1.84 U667.5 41.96 7.47 15.07 U675.4 8.21 1.46 3.40 U690.7 18.02 3.21 5.82706.9 11.96 2.13 2.70 U716.3 15.87 2.82 5.88 U732.3 32.81 5.84 8.82 U737.4 11.63 2.07 4.38 U744.1 2.32 0.41 0.80 U751.4 15.92 2.83 8.95 U753.7 35.50 6.32 8.43 U770.7 14.92 2.66 3.86 U784.9 7.64 1.36 2.27 U789.4 4.21 0.75 1.72 U800.4 3.48 0.62 1.01812.5 0.96 0.17 0.37831.4 1.35 0.24 0.37 U833.9 0.51 0.09 0.43 U856.2 2.59 0.46 0.98882.7 1.75 0.31 0.40902.4 1.10 0.20 0.43944.4 0.90 0.16 0.64959.0 0.51 0.09 0.371006.40.60 0.11 0.341018.54.81 0.86 1.841055.96.23 1.11 2.18 U1063.00.79 0.14 0.55 U1077.51.06 0.19 0.491093.81.40 0.25 0.641100.01.16 0.21 0.371115.81.54 0.27 0.551130.30.87 0.16 0.371152.10.70 0.12 0.40 U1157.53.17 0.56 1.65 U1180.81.25 0.22 0.58 U1185.41.47 0.26 0.52 U1197.12.56 0.45 0.771211.60.40 0.07 0.341239.00.65 0.11 0.431289.11.39 0.25 0.611306.50.91 0.16 0.401414.61.08 0.19 0.34完整細(xì)胞MALDIMeningo 10/M97251540Data:a0019.19 3 Jul 97 15:28 Ca1:test 25 ADr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志1446.50.56 0.10 0.341471.80.92 0.16 0.431560.51.16 0.21 0.401607.21.87 0.33 0.981635.40.80 0.14 0.371644.91.55 0.28 0.671689.71.16 0.21 0.462692.91.24 0.22 0.492862.91.39 0.25 0.773313.01.07 0.19 0.405145.41.08 0.19 0.376424.72.65 0.47 0.646520.68.67 1.54 1.936619.546.42 8.26 8.58 U6657.26.34 1.13 1.47 U6686.60.85 0.15 0.46 U6695.91.04 0.18 0.43 U完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志504.20.950.03 0.18512.11.900.06 0.25519.05.480.18 0.28525.947.29 1.60 1.59535.50.950.03 0.18540.10.860.03 0.15544.1100.00 3.38 6.62 U549.45.700.19 0.49 U553.413.98 0.47 0.80 U566.410.68 0.36 0.74575.60.140.00 0.09578.30.720.02 0.12582.019.10 0.65 1.10588.47.060.24 0.49604.317.19 0.58 0.74609.50.320.01 0.09610.60.770.03 0.09621.25.430.18 0.21628.35.160.17 0.18634.70.450.02 0.09636.11.580.05 0.18645.77.780.26 0.37652.78.370.28 0.52657.83.800.13 0.28662.40.950.03 0.12667.042.22 1.43 1.93675.41.310.04 0.15678.10.630.02 0.09684.70.270.01 0.09690.412.58 0.42 0.58694.71.400.05 0.18706.211.67 0.39 0.49715.519.28 0.65 0.92731.545.70 1.54 1.41746.22.710.09 0.21754.024.03 0.81 0.80765.20.680.02 0.12770.79.140.31 0.58775.40.630.02 0.09781.01.810.06 0.15793.23.710.13 0.25807.90.770.03 0.12813.81.400.05 0.15817.31.990.07 0.15823.50.360.01 0.12832.50.900.03 0.15835.50.500.02 0.12847.90.500.02 0.12858.71.450.05 0.21864.20.270.01 0.09869.81.220.04 0.15874.01.000.03 0.15876.20.860.03 0.15879.93.620.12 0.31890.00.270.01 0.09897.03.570.12 0.31912.40.270.01 0.09完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志919.61.40 0.05 0.12931.92.76 0.09 0.15937.71.72 0.06 0.18945.62.17 0.07 0.15948.20.50 0.02 0.12956.62.13 0.07 0.18994.50.59 0.02 0.12998.30.32 0.01 0.091004.9 0.50 0.02 0.121017.3 0.72 0.02 0.121041.2 0.72 0.02 0.121057.2 0.50 0.02 0.091088.1 2.71 0.09 0.281096.9 2.71 0.09 0.151116.7 1.40 0.05 0.181132.2 0.50 0.02 0.121137.3 0.32 0.01 0.091156.2 2.44 0.08 0.211160.4 0.54 0.02 0.121163.6 3.35 0.11 0.311199.7 0.27 0.01 0.091224.1 0.32 0.01 0.091248.4 0.50 0.02 0.121266.8 0.68 0.02 0.121274.2 1.22 0.04 0.151286.8 0.27 0.01 0.091298.3 1.27 0.04 0.151307.9 0.50 0.02 0.121323.0 0.45 0.02 0.091338.9 1.45 0.05 0.181362.8 1.18 0.04 0.121370.5 0.81 0.03 0.151379.3 0.50 0.02 0.121405.4 2.53 0.09 0.181428.9 0.77 0.03 0.121584.9 0.86 0.03 0.121644.9 0.50 0.02 0.121718.6 0.63 0.02 0.091785.9 0.50 0.02 0.091790.7 0.54 0.02 0.121998.1 0.45 0.02 0.092073.2 0.27 0.01 0.092137.0 0.45 0.02 0.092217.8 1.36 0.05 0.122227.6 0.27 0.01 0.092231.2 0.95 0.03 0.122235.6 2.22 0.07 0.212248.2 1.00 0.03 0.122266.6 0.86 0.03 0.152275.2 1.54 0.05 0.122292.8 2.62 0.09 0.152299.6 2.81 0.09 0.182317.3 1.04 0.04 0.152323.2 3.94 0.13 0.152332.4 0.45 0.02 0.092336.9 2.40 0.08 0.252342.9 0.86 0.03 0.12完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志2348.82.81 0.09 0.212354.41.00 0.03 0.152358.90.27 0.01 0.092366.84.25 0.14 0.212371.81.09 0.04 0.122378.31.99 0.07 0.122383.82.90 0.10 0.182390.31.72 0.06 0.152401.95.20 0.18 0.282414.90.59 0.02 0.092418.15.66 0.19 0.182433.55.61 0.19 0.212448.07.96 0.27 0.282466.77.01 0.24 0.252477.54.30 0.15 0.312482.70.72 0.02 0.122490.31.09 0.04 0.152495.51.00 0.03 0.152504.03.44 0.12 0.212517.28.05 0.27 0.372525.86.74 0.23 0.462546.315.610.53 0.552563.510.000.34 0.462585.611.310.38 0.342601.43.76 0.13 0.252608.24.89 0.17 0.212619.323.120.78 0.802644.616.020.54 0.862660.622.900.77 0.772691.924.930.84 0.522707.71.22 0.04 0.152717.02.13 0.07 0.122748.246.381.57 0.922768.124.570.83 0.402824.127.870.94 0.522850.815.520.52 0.61 U2862.939.951.35 1.69 U2875.16.70 0.23 0.55 U2892.823.620.80 0.52 U2901.07.78 0.26 0.58 U2925.522.900.77 0.672945.027.470.93 0.522972.212.220.41 0.55 U2981.514.030.47 0.45 U3024.529.230.99 0.433039.120.540.69 0.433066.315.110.51 0.61 U3073.17.38 0.25 0.58 U3078.30.27 0.01 0.093103.631.541.07 0.70 U3112.014.300.48 0.58 U3127.97.19 0.24 0.373141.613.350.45 0.52 U3151.210.050.34 0.55 U3163.915.200.51 0.61 U3173.510.500.35 0.64 U3185.315.340.52 0.52 U完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志3194.93.440.12 0.313204.56.830.23 0.613219.532.26 1.09 0.61 U3244.226.92 0.91 0.61 U3283.718.55 0.63 0.583308.111.49 0.39 0.463331.016.15 0.55 0.403339.75.520.19 0.49 U3349.013.76 0.46 0.77 U3367.114.25 0.48 0.55 U3379.211.18 0.38 0.58 U3401.227.51 0.93 0.58 U3421.714.93 0.50 0.61 U3435.59.910.33 0.49 U3442.28.280.28 0.55 U3450.010.45 0.35 0.52 U3465.09.910.33 0.49 U3473.310.63 0.36 0.64 U3490.116.43 0.55 0.67 U3511.326.65 0.90 0.74 U3529.91.860.06 0.183554.632.08 1.08 0.743569.316.15 0.55 0.49 U3591.913.03 0.44 0.67 U3605.614.39 0.49 0.43 U3628.922.49 0.76 0.80 U3647.715.97 0.54 0.70 U3666.034.07 1.15 0.74 U3683.210.90 0.37 0.58 U3694.71.090.04 0.123716.625.43 0.86 1.04 U3731.012.31 0.42 0.52 U3750.117.69 0.60 0.743766.313.98 0.47 0.49 U3779.118.51 0.63 0.95 U3794.825.66 0.87 0.92 U3818.89.770.33 0.403870.953.03 1.79 0.61 U3881.06.560.22 0.49 U3893.312.08 0.41 0.61 U3908.18.600.29 0.403927.623.67 0.80 0.523948.41.950.07 0.153962.78.960.30 0.52 U3983.020.41 0.69 0.43 U4006.315.38 0.52 0.40 U4046.530.14 1.02 0.70 U4073.010.09 0.34 0.64 U4094.216.43 0.55 0.55 U4109.316.38 0.55 0.55 U4133.012.49 0.42 0.374156.710.27 0.35 0.46 U4171.417.24 0.58 0.64 U4185.411.40 0.39 0.64 U4205.712.22 0.41 0.58 U4220.48.690.29 0.40 U4237.018.24 0.62 0.52 U完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.93 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志4261.017.06 0.58 0.55 U4275.320.59 0.70 0.67 U4322.413.71 0.46 0.524336.73.800.13 0.184371.029.68 1.00 0.464392.921.90 0.74 0.404438.820.41 0.69 0.494465.317.69 0.60 0.494533.843.48 1.47 0.494577.925.43 0.86 0.584623.418.10 0.61 0.434645.312.31 0.42 0.314666.617.60 0.59 0.80 U4695.716.70 0.56 0.52 U4706.19.050.31 0.46 U4717.24.890.17 0.214748.420.27 0.68 0.61 U4774.516.38 0.55 0.37 U4800.70.630.02 0.094808.53.710.13 0.214825.616.15 0.55 0.43 U4857.814.71 0.50 0.55 U4887.622.71 0.77 0.43 U4918.017.60 0.59 0.37 U4946.62.620.09 0.254973.917.42 0.59 0.525003.315.70 0.53 0.465018.04.250.14 0.255030.11.090.04 0.125058.329.19 0.99 0.555094.76.150.21 0.315127.811.00 0.37 0.46 U5144.114.57 0.49 0.55 U5159.71.990.07 0.155168.51.900.06 0.155186.222.17 0.75 0.435247.722.99 0.78 0.345277.90.680.02 0.125288.92.990.10 0.185311.617.10 0.58 0.405348.97.240.24 0.345361.44.300.15 0.285383.64.160.14 0.215400.92.080.07 0.215407.21.580.05 0.185433.612.26 0.41 0.285458.12.530.09 0.185468.65.570.19 0.255489.61.310.04 0.125506.42.760.09 0.155520.410.72 0.36 0.405547.911.00 0.37 0.285581.01.900.06 0.185605.16.650.22 0.215612.94.800.16 0.185629.20.450.02 0.095644.11.900.06 0.18完整細(xì)胞MALDIMeningo 15/M97251545Data:a0029.9 3 Jul 97 16:14 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志5654.00.68 0.02 0.125664.02.71 0.09 0.185674.74.66 0.16 0.185711.14.98 0.17 0.155721.82.13 0.07 0.155736.13.85 0.13 0.185747.65.48 0.18 0.185770.61.67 0.06 0.125783.53.62 0.12 0.185807.31.72 0.06 0.095828.91.36 0.05 0.125849.98.46 0.29 0.215883.21.09 0.04 0.125917.34.12 0.14 0.185939.94.25 0.14 0.215953.02.58 0.09 0.185970.62.26 0.08 0.155981.51.76 0.06 0.155995.43.12 0.11 0.156035.18.87 0.30 0.216089.50.63 0.02 0.096129.51.00 0.03 0.126148.02.76 0.09 0.186179.21.00 0.03 0.126190.32.26 0.08 0.156221.625.52 0.86 0.776242.59.28 0.31 0.316268.713.53 0.46 0.216313.70.81 0.03 0.096323.52.76 0.09 0.256331.00.81 0.03 0.096418.61.95 0.07 0.156447.52.53 0.09 0.216521.30.95 0.03 0.126535.12.40 0.08 0.126558.00.45 0.02 0.096573.40.90 0.03 0.126581.00.45 0.02 0.096596.44.12 0.14 0.186649.51.49 0.05 0.126661.90.45 0.02 0.096692.810.0 0.34 0.376710.60.45 0.02 0.096726.92.67 0.09 0.216785.243.7 1.48 1.076847.62.31 0.08 0.186876.62.04 0.07 0.186908.80.68 0.02 0.126923.01.22 0.04 0.126937.10.63 0.02 0.09完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志500.645.92 4.17 6.65 U516.8100.00 9.07 8.95 U525.924.35 2.21 3.22 U533.321.39 1.94 2.85540.30.360.03 0.12545.058.34 5.29 6.89554.91.930.17 0.31556.30.340.03 0.18558.11.710.15 0.52 U560.11.980.18 0.64 U561.60.150.01 0.12567.07.030.64 1.32578.10.570.05 0.18583.15.830.53 0.95589.11.830.17 0.37593.70.540.05 0.12594.60.300.03 0.12602.70.200.02 0.12605.75.650.51 1.04613.00.510.05 0.18615.60.170.02 0.09621.93.310.30 0.46627.63.580.33 0.58633.50.170.02 0.09635.90.460.04 0.15645.75.390.49 0.70650.50.200.02 0.12654.61.010.09 0.18659.713.80 1.25 2.14667.810.16 0.92 1.47675.929.64 2.69 4.04687.70.100.01 0.09691.927.61 2.50 3.43700.20.690.06 0.18707.47.190.65 0.83 U716.812.19 1.11 1.35 U732.625.50 2.31 2.30 U738.211.85 1.07 1.62 U745.21.560.14 0.34754.033.43 3.03 2.48766.00.100.01 0.09770.78.640.78 0.77786.05.650.51 0.89790.00.100.01 0.09794.81.540.14 0.31800.12.470.32 0.37813.01.050.10 0.28817.00.050.00 0.09824.90.510.05 0.18830.10.360.03 0.18833.60.560.05 0.18838.50.850.08 0.15855.33.520.32 0.37867.53.130.28 0.25871.50.390.04 0.15873.70.190.02 0.12880.40.510.05 0.15完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志883.2 2.25 0.20 0.18893.7 0.63 0.06 0.12898.7 1.10 0.10 0.25905.6 0.19 0.02 0.12913.8 0.19 0.02 0.09915.6 0.27 0.02 0.12923.9 2.16 0.20 0.18927.9 0.71 0.06 0.18942.4 2.62 0.24 0.28952.6 0.51 0.05 0.15956.6 0.19 0.02 0.12966.3 1.81 0.16 0.28980.2 3.16 0.29 0.35998.3 0.32 0.03 0.121001.61.94 0.18 0.281010.60.12 0.01 0.091014.20.29 0.03 0.151018.81.35 0.12 0.311040.30.10 0.01 0.091042.70.71 0.06 0.211051.90.19 0.02 0.121056.84.02 0.36 0.581063.90.27 0.02 0.121078.82.71 0.25 0.461085.90.29 0.03 0.091091.60.52 0.05 0.211094.70.98 0.09 0.151100.30.83 0.08 0.211117.02.05 0.19 0.181121.80.78 0.07 0.281128.40.17 0.02 0.091132.22.60 0.24 0.341146.90.49 0.04 0.121153.30.17 0.02 0.091158.82.71 0.25 0.431164.00.98 0.09 0.181170.10.12 0.01 0.091175.31.44 0.13 0.281180.20.57 0.05 0.211189.31.37 0.12 0.251192.50.12 0.01 0.091204.70.47 0.04 0.121208.60.36 0.03 0.121210.60.12 0.01 0.091227.10.98 0.09 0.311234.70.34 0.03 0.121254.40.63 0.06 0.181259.10.79 0.07 0.181287.80.85 0.08 0.181292.91.35 0.12 0.281304.80.19 0.02 0.121315.10.19 0.02 0.121330.90.44 0.04 0.181339.90.56 0.05 0.211346.10.36 0.03 0.151375.40.39 0.04 0.151401.20.27 0.02 0.12完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5:2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志1435.70.42 0.04 0.121469.60.19 0.02 0.121492.90.73 0.07 0.181513.80.17 0.02 0.091550.10.19 0.02 0.091558.70.69 0.06 0.151609.51.79 0.16 0.251623.50.34 0.03 0.121628.50.12 0.01 0.091663.00.34 0.03 0.121666.90.46 0.04 0.151687.80.86 0.08 0.251711.60.41 0.04 0.121714.30.32 0.03 0.121734.80.17 0.02 0.091753.30.12 0.01 0.091863.90.66 0.06 0.121877.00.17 0.02 0.091901.70.19 0.02 0.091951.10.12 0.01 0.091987.20.19 0.02 0.122056.50.30 0.03 0.152069.80.27 0.02 0.122093.50.66 0.06 0.212118.30.34 0.03 0.122136.21.69 0.15 0.152150.20.27 0.02 0.122156.30.54 0.05 0.122160.70.12 0.01 0.092166.00.25 0.02 0.122172.21.59 0.14 0.182185.80.39 0.04 0.122192.90.10 0.01 0.092198.20.10 0.01 0.092207.60.24 0.02 0.092215.60.24 0.02 0.092220.51.29 0.12 0.212225.80.10 0.01 0.092234.31.84 0.17 0.342244.60.98 0.09 0.212251.80.42 0.04 0.152279.20.36 0.03 0.152287.81.15 0.10 0.212301.00.44 0.04 0.122310.01.03 0.09 0.182321.40.49 0.04 0.152325.10.27 0.02 0.122331.90.27 0.02 0.122335.10.27 0.02 0.122339.71.44 0.13 0.182350.21.10 0.10 0.182362.21.23 0.11 0.182375.00.44 0.04 0.152381.02.08 0.19 0.212418.62.65 0.24 0.372428.80.47 0.04 0.182439.60.64 0.06 0.15完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65.tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志2447.50.85 0.08 0.182452.60.79 0.07 0.282460.13.31 0.30 0.252476.60.10 0.01 0.092483.20.42 0.04 0.152490.30.51 0.05 0.182495.50.29 0.03 0.122499.20.42 0.04 0.152507.80.32 0.03 0.122518.71.91 0.17 0.282531.50.17 0.02 0.092539.10.51 0.05 0.182548.28.59 0.78 0.372582.20.59 0.05 0.152590.40.83 0.08 0.152599.51.50 0.14 0.312604.30.17 0.02 0.092608.70.81 0.07 0.212614.50.44 0.04 0.152632.43.21 0.29 0.182645.55.17 0.47 0.462660.63.92 0.36 0.492673.30.10 0.01 0.092682.12.03 0.18 0.282693.43.55 0.32 0.372703.70.10 0.01 0.092711.10.64 0.06 0.152717.51.20 0.11 0.282728.42.00 0.18 0.182736.30.86 0.08 0.212741.20.42 0.04 0.122750.72.20 0.20 0.282759.10.24 0.02 0.092766.60.64 0.06 0.152772.50.25 0.02 0.122777.01.62 0.15 0.252786.50.36 0.03 0.122793.01.71 0.15 0.212805.02.23 0.20 0.342814.52.59 0.23 0.182834.60.32 0.03 0.122839.20.37 0.03 0.152843.71.54 0.14 0.252851.80.25 0.02 0.122862.45.87 0.53 0.642876.61.00 0.09 0.252892.35.50 0.50 0.462911.21.45 0.13 0.212917.30.10 0.01 0.092920.90.51 0.05 0.152928.61.39 0.13 0.182937.80.25 0.02 0.122945.01.67 0.15 0.252954.70.85 0.08 0.212963.53.64 0.33 0.402977.92.13 0.19 0.312990.82.98 0.27 0.28完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志3024.56.27 0.57 0.373036.50.32 0.03 0.123040.20.61 0.06 0.183045.92.13 0.19 0.253061.02.69 0.24 0.313077.81.47 0.13 0.213085.21.40 0.13 0.183103.16.78 0.61 0.493142.75.61 0.51 0.373150.10.91 0.08 0.283176.27.39 0.67 0.493194.96.48 0.59 0.403213.10.71 0.06 0.153222.71.22 0.11 0.253230.33.38 0.31 0.313251.30.66 0.06 0.123259.91.74 0.16 0.373277.74.80 0.44 0.46 U3287.52.54 0.23 0.40 U3297.33.33 0.30 0.40 U3326.66.81 0.62 0.463340.31.00 0.09 0.253349.63.92 0.36 0.46 U3360.63.65 0.33 0.34 U3373.70.30 0.03 0.093400.77.20 0.65 0.553421.73.13 0.28 0.313444.46.34 0.58 0.463461.61.42 0.13 0.153485.63.28 0.30 0.313508.54.45 0.40 0.463516.40.51 0.05 0.153524.80.56 0.05 0.153529.96.66 0.60 0.40 U3558.64.08 0.37 0.49 U3578.43.13 0.28 0.343609.57.91 0.72 0.373631.20.81 0.07 0.253642.62.23 0.20 0.283654.65.17 0.47 0.373676.34.53 0.41 0.463699.92.16 0.20 0.343714.36.26 0.57 0.40 U3737.42.82 0.26 0.37 U3748.40.46 0.04 0.153761.73.97 0.36 0.343777.91.50 0.14 0.373783.80.59 0.05 0.123791.30.30 0.03 0.123797.73.91 0.35 0.46 U3817.65.12 0.46 0.43 U3829.31.01 0.09 0.213847.43.28 0.30 0.493856.31.76 0.16 0.313870.40.98 0.09 0.153890.44.45 0.40 0.403905.72.93 0.27 0.25完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志3940.112.16 1.10 0.52 U3970.41.84 0.17 0.43 U3982.41.12 0.10 0.153996.72.47 0.22 0.254010.51.72 0.16 0.284021.90.54 0.05 0.154039.94.79 0.43 0.584050.71.50 0.14 0.344064.05.56 0.50 0.284096.66.i9 0.56 0.404133.04.62 0.42 0.344157.97.29 0.66 0.404224.17.59 0.69 0.404246.90.34 0.03 0.124257.32.00 0.18 0.254277.76.07 0.55 0.344300.62.99 0.27 0.43 U4343.59.74 0.88 0.40 U4371.02.28 0.21 0.434382.91.29 0.12 0.184394.85.33 0.48 0.55 U4420.64.75 0.43 0.43 U4442.62.64 0.24 0.464450.80.25 0.02 0.124462.21.96 0.18 0.374473.50.37 0.03 0.094487.53.52 0.32 0.314507.82.43 0.22 0.404547.96.80 0.62 0.374563.23.20 0.29 0.284583.02.52 0.23 0.434597.70.90 0.08 0.184605.42.74 0.25 0.314620.90.36 0.03 0.124640.28.47 0.77 0.434673.71.25 0.11 0.314686.00.81 0.07 0.254709.44.29 0.39 0.284742.59.33 0.85 0.344774.50.46 0.04 0.154786.93.28 0.30 0.184823.05.75 0.52 0.344851.93.58 0.33 0.314871.70.59 0.05 0.154895.54.99 0.45 0.584921.31.22 0.11 0.184939.33.21 0.29 0.284965.23.20 0.29 0.284991.32.42 0.22 0.285035.54.97 0.45 0.255046.21.17 0.11 0.285069.73.79 0.34 0.215093.31.08 0.10 0.155104.10.30 0.03 0.095109.60.30 0.03 0.095119.70.73 0.07 0.185129.20.24 0.02 0.09完整細(xì)胞MALDIMeningo 20/M97251682Data:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALD1 2 V5.2.1:+Linear High Power:65,tDE @ 1000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志5138.01.25 0.11 0.155154.31.52 0.14 0.315162.41.76 0.16 0.285178.70.83 0.08 0.125213.52.10 0.19 0.255234.70.68 0.06 0.155242.20.41 0.04 0.125253.20.51 0.05 0.125272.41.15 0.10 0.125288.22.10 0.19 0.285303.40.54 0.05 0.155320.63.79 0.34 0.315355.11.39 0.13 0.185364.10.47 0.04 0.155371.80.39 0.04 0.155392.60.86 0.08 0.155411.40.46 0.04 0.125427.41.17 0.11 0.155461.60.83 0.08 0.125470.70.59 0.05 0.155488.92.42 0.22 0.185522.51.40 0.13 0.215531.00.78 0.07 0.185541.50.51 0.05 0.125564.81.37 0.12 0.125574.00.36 0.03 0.095585.30.22 0.02 0.095597.30.24 0.02 0.095617.80.47 0.04 0.155642.00.30 0.03 0.125658.30.83 0.08 0.185668.30.24 0.02 0.095722.50.39 0.04 0.125733.30.66 0.06 0.125745.40.30 0.03 0.095762.70.22 0.02 0.095808.70.52 0.05 0.095839.01.07 0.10 0.215862.20.17 0.02 0.095913.00.32 0.03 0.125919.50.17 0.02 0.095956.71.57 0.14 0.126017.40.86 0.08 0.186089.50.25 0.02 0.126108.00.22 0.02 0.096130.20.56 0.05 0.156142.80.68 0.06 0.186178.40.57 0.05 0.156273.20.32 0.03 0.126297.20.30 0.03 0.096319.71.32 0.12 0.126394.40.47 0.04 0.096533.60.24 0.02 0.096554.20.17 0.02 0.096625.60.30 0.03 0.096707.50.32 0.03 0.126718.30.17 0.02 0.09完整細(xì)胞MALDIMeningo 20/M9725i682DAta:a0039.19 3 Jul 97 16:28 Cal:test 25 Apr 97 11:25Kratos Kompact MALDI 2 V5.2.1:+Linear High Power:65,tDE @ l000(bin 56)質(zhì)量 面積百分比 總百分比 峰值(mV)標(biāo)志6753.30.59 0.05 0.186790.620.09 1.82 1.356841.40.41 0.04 0.126864.10.39 0.04 0.126879.81.20 0.11 0.156893.90.64 0.06 0.1全文摘要
本發(fā)明涉及鑒定微生物的方法和裝置。本發(fā)明利用一系列已知微生物的基體輔助激光解吸電離飛行時間質(zhì)譜(MALDI－TOF－MS)的質(zhì)譜數(shù)據(jù)。該質(zhì)譜數(shù)據(jù)包括在包含每一種已知微生物的質(zhì)譜數(shù)據(jù)的數(shù)據(jù)庫中。制備未鑒定微生物的樣品;然后通過MALDI－TOF－MS技術(shù)進(jìn)行分析,得到未知微生物的質(zhì)譜數(shù)據(jù)。然后利用合適的比較裝置將該數(shù)據(jù)與數(shù)據(jù)庫中的質(zhì)譜數(shù)據(jù)進(jìn)行比較。質(zhì)譜數(shù)據(jù)類似指明未知微生物所屬的屬,而質(zhì)譜數(shù)據(jù)相同則指明具體微生物。用于該分析的裝置的優(yōu)點在于:一次設(shè)置和校準(zhǔn)后其使用相對簡單。
文檔編號H01J49/00GK1234906SQ9719917
公開日1999年11月10日 申請日期1997年8月26日 優(yōu)先權(quán)日1996年8月27日
發(fā)明者M·A·克萊頓, S·N·戴維, V·愛德華斯瓊斯, D·B·戈爾頓 申請人:曼徹斯特都市大學(xué)