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一種陽(yáng)性質(zhì)粒分子pBI121-Screening及其應(yīng)用_4

文檔序號(hào):8334125閱讀:來(lái)源:國(guó)知局
aaaactcaggccgcagtcggtaacctcgcgcata,cagccgggca5040 gtgacgtcatcgtctgcgcggaaatggacgaacagtggggctatgtcggggctaaatcgc5100 gccagcgctggctgttttacgcgtatgacagtctccggaagacggttgttgcgca.cgtat5160
[0147] tcggtgaacgcactatggcgacgctggggcgtcttatgagcctgctgtcaccctttgacg5220tggtgatatggatgacggatggctggccgctgtatgaatcccgcctgaagggaaagctgc5280 acgtaatcagcaagcgatatacgcagcgaattgagcggcataacctgaatctgaggcagc5340 acctggcacggctgggacggaagtcgctgtcgttctcaaaatcggtggagctgcatgaca5400 aagtcatcgggcattatctgaacataaaacactatcaataagttggagtcattacccaat5460 tatgatagaatttacaagctataaggttattgtcctgggtttcaagcattagtccatgca5520 agtttttatgctttgcccattctatagatatattgataagcgcgctgcctatgccttgcc5580 ccctgaaatccttacatacggcgatatcttctatataaaagatatattatcttatcagta5640 ttgtcaatatattcaaggcaatctgcct.cctcatxctxttcatcctcttcgtcttggtag5700 ctttttaaatatggcgcttcatagagtaattctgtaaaggtccaattctcgttttcatac5760 ctcggtataatcttacctatcacctcaaatggttcgctgggtttatcgcacccccgaaca5820 cgagcacggcacccgcgaccactatgccaagaatgcccaaggtaaaaa.ttgccggccccg5880 ccatgaagtccgtgaatgccccgacggccgaagtgaa.gggcaggccgccacccaggccgc5940 cgccctcactgcccggcacctggtcgctgaatgtcgatgccagcacctgcggcacgtcaa6000 tgcttccgggcgtcgcgctcgggctgatcgcccatcccgttactgccccgatcccggcaa6060 tggcaaggactgccagcgctgccatttttggggtgaggccgttcgcggccgaggggcgca6120 gcccctggggggatgggaggcccgcgttagcgggccgggagggttcgagaagggggggca, 6180 ccccccttcggcgtgcgcggtcacgcgcacagggcgcagccctggttaaaaacaaggttt6240 ataaatattggtttaaaagcaggttaaaagacaggltagcggtggccgaaaaacgggcgg6300 aaaccctlgcaaatgclggattttctgcctgtggacagcccctcaaatglcaataggtgc6360 gcccctcatctglcagcactctgcccctcaagtgtcaaggatcgcgcccctcatctgtca6420 gtagtcgcgcccctcaagtgtcaataccgcagggcacttatccccaggcttgtccacatc6480 alctgtgggaaactcgcgtaaaatcaggcgtttlcgccgatttgcgaggcIggccagclc6540 cacgtcgccggccgaaatcgagcctgcccctcatctgtcaacgccgcgccgggtgagtcg6600 gcccctcaagtgtcaacgtccgcccctcatctgtcagtgagggccaagttttccgcgagg6660 tatccacaacgccggcggccgcggtgtctcgcacacggcttcgacggcgtttctggcgcg6720 tttgcagggccatagacggccgccagcccagcggcgagggcaaccagcccggtgagcgtc6780 gcaaaggcgctcggtcttgccttgctcgtcggtgatgtacttcaccagctccgcgaagtc6840 gctcttcttgatggagcgcatggggacgtgcttggcaatcacgcgcaccccccggccgtt6900
[0148] ttagcggctaaaaaagtcatggctctgccctcgggcggaccacgcccatcatgaccttgc6960caagctcgtcctgcttctxttcgatcttcgccagcagggcgaggatcgtggcatcaccga7020 accgcgccgtgcgcgggtcgtcggtgagccagagtttcagcaggccgcccaggcggccca7080 ggtcgccattgatgcgggccagctcgcggacgtgctcatagtcca.cgacgcccgtgattt7140 tgtagccctggccgacggccagcaggtaggccgacaggctcatgccggccgccgccgcct7200 tttcctcaatcgctcttcgttcgtctggaaggcagtaca.ccttgataggtgggctgccct7260 tcctggttggcttggtttcatcagccatccgcttgccctcatctgtta.cgccggrggtag7320 ccggccagcctcgcagagcaggattcccgttgagcaccgccaggtgcgaataagggacag7380 tgaagaa.ggaa.cacccgctcgcgggtgggcctacttcacctatcctgcccggctgacgcc7440 gttgga.tacaccaa.ggaaagtctacacgaaccctttggcaaaatcctgtatatcgtgcga7500 aa.aa.ggatgga.tataccga.aaaaatcgctataatgaccccgaagcagggttatgcagcgg7560 a.aaagcgccacgcttcccgaagggagaaaggcggacaggtatccggtaagcggcagggtc7620 ggaacaggagagcgcacgagggagcttccagggggaaacgcctggtatctttatagtcct7680 gtcgggtttcgccacctctgacttgagcgtcgatttttgtgatgctcgtcaggggggcgg7740 agcctatggaaaaacgccagcaacgcggcctttltacggttcctggccttttgctggcct7800 tllgctcacatgttctttcctgcgtlaicccctgattcigtggataaccgtattaccgcc7860 tttgagtgagctgataccgctcgccgcagccgaacgaccgagcgcagcgagtcagtgagc7920 gaggaagcggaagagcgccagaaggccgccagagaggccgagcgcggccgtgaggcttgg7980 acgctagggcagggcatgaaaaagcccgtagcgggctgctacgggcgtctgacgcggtgg8040 aaagggggaggggatgttgtctacatggctctgctgtagtgagtgggttgcgctccggca8100 gcggtcctgatcaatcgtcaccctttctcggtccttcaacgttcctgacaacgagcctcc8160 ttttcgccaatccatcgacaatcaccgcgagtccctgctcgaacgctgcgtccggaccgg8220 cttcgtcgaaggcgtctatcgcggcccgcaacagcggcgagagcggagcctgttcaacgg8280 tgccgccgcgctcgccggcatcgctgtcgccggcctgctcctcaagcacggccccaacag8340 tgaagtagctgattgtcatcagcgcattgacggcgtccccggccgaaaaacccgcctcgc8400 agaggaagcgaagctgcgcgtcggccgtttccatctgcggtgcgcccggtcgcgtgccgg8460 catggatgcgcgcgccatcgcggtaggcgagcagcgcctgcctgaagctgcgggcattcc8520 cgatcagaaatgagcgccagtcgtcgtcggctctcggcaccgaatgcgtatgattctccg8580 ccagcatggcttcggccagtgcgtcgagcagcgcccgcttgttcctgaagtgccagtaaa8640
[0149] gcgccggctg ctgaaccccc aaccgttccg ccagtttgcg tgtcgtcaga ccgtctacgc 8700 cgacctcgtt caacaggtcc agggcggcac ggatcactgt attcggctgc aactttgtca 8760 tgcttgacac tttatcactg ataaacataa tatgtccacc aacttatcag tgataaagaa 8820 tccgcgcgtt caatcggacc agcggaggct ggtccggagg ccagacgtga aacccaacat 8880 acccctgatc gtaattctga gcactgtcgc gctcgacgct gtcggcatcg gcctgattat 8940 gccggtgctg ccgggcctcc tgcgcgatct ggttcactcg aacgacgtca ccgcccacta 9000 tggcattctg ctggcgctgt atgcgttggt gcaatttgcc tgcgcacctg tgctgggcgc 9060 gctgtcggat cgtttcgggc ggcggccaat cttgctcgtc tcgctggccg gcgccagatc 9120 tggggaaccc tgtggttggc atgcacatac aaatggacga acggataaac cttttcacgc 9180 ccttttaaat atccgattat tctaataaac gctcttttct cttaggttta cccgccaata 9240 tatcctgtca aacactgata gtttatctgt ttactcgtca agtgtcatct cctgaagtgg 9300 actggagcta tggggagcct actgaaatgt taactccggt tccactgacg gagagggaag 9360 cggtgagagt gctggtgcgt acattgtgcg cattccgtgc ggtccaaggg acaagtacct 9420 ccgtaaagag ccctgtggcc ttacctccaa. gagtttgtcg acggagctct cgcgcatatc 9480 tgaacatgtc caaggctctg ggggaacagg ttagcaatgg gaagctggtc ttgccatatg 9540 taatccatgg cttgcgcctg aacggatatc tttcagttig taaccaccgg atgacgcacg 9600 gacggctcgg atcatcccga aaagatcaac cgtggtgagc gttttgcagt ctatgttgtg 9660 ctgccaatgt ggcctgaagg acctcctgct agtggatcag gggtgaggat agggttctct 9720 gctgccacgg gactcgacat acctggggaa tcgcatgacg tgctttcttg gtcttttgct 9780 tccaatttgc cacacgctag cagtaacatt gatcctttgg atcttacaag ctttgtgttg 9840 catgaggcca tctaaatgtg acagatcgaa ggaagaaagt gtaataagac gactctcact 9900 actcgatcgc gccctctact ccacccccat ccacatttgg gacaaagaaa ccggtagcgt 9960 tgccagcttc gccgcttcct tcaacttcac cltctatgcc cctgacacaa aaaggcttgc 10020 agatgggctg gcctctaatc attgttatga tgagatttga acttttacaa attatgatat 10080 tgttgtcttt gaatccttgg taataatgat gatgtatgag tatgagaatg aaagtaatcc 10140 caaagttggt ttatttttac tgaacacaga gaggttggga atctgaaaaa gcctttcacg 10200 cctccaaagg aggtgcctgt tcagatcacc cactccatgc cgcctcacaa gattgagatc 10260 tttaaatctt tggagggctg ggctgagaac aacattctga ctcacctcaa tccttccgtt 10320 tcctcgccga ggcctagagg tcgtcctcct aaggcgaaag gaccttcctc ggaggtggag 10380
[0150] acgaaagttg cggcaccgag tggctccggg aggccacgtg gacgaccgcc gaagaagcag 10440 aagacggaat ccgaggcggt taaagccgat gttgaacctg cggaggct.cc ggctggggag 10500 cggagagggc gtggaaggcc agggcttccg tgatatgcac cagaaagtgg agcacataag 10560 gactggggac a.cca.tcgcta cacatcccgg tgtagcccaa tggttctaca. acgacgga.aa. 10620 ccaaccactt gtcatcgttt ccgtcctcga tttagccagc caccagctcc caatcctttg 10680 acatctgctc cgaagcaaag tcagagcgct gcaatgcaaa acggaacgag tgggggcagc 10740 agcgcgagcaccgccgcgccggtgtccgga cccaaagrtg atcatccatc agctcctgtc 10800 accaagagag aaatcgacgg tggatgctaa ggctgatgca gctccggcta cagatgcggc 10860 ggcgagtgct ccttatgaca gggaggataa tgaacctggc cctttgtcgc aggaa.cagag 10920 gtgttcaagg cggccgaaat aggttgccgc ctgcggcgga atcgccaccc accgtgaagt 10980 tcaccgtttc gcaatggagg aacaccaaac tgaaggcggg aaacgacaat ctgatcatga 11040 gcggagaatt aagggagtca cgttatgacc cccgccgatg acgcgggaca agccgtttta 11100 cgtttggaac tgacagaacc gcaacgttga aggagccact cagccgcggg tttctggagt 11160 ttaatgagct aagcacatac gtcagaaacc attattgcgc gttcaaaagt cgcctaaggt 11220 cactatcagc tagcaaatal itcttgtcaa aaatgctcca ctgacgttcc ataaattccc 11280 clcggtatcc aattagagtc tcalatlcac tctcaalcca aataalctgc accggatctg 11340 gatcgtttcg catgattgaa caagatggat tgcacgcagg ttctccggcc gcttgggtgg 11400 agaggctatt cggctatgac tgggcacaac agacaatcgg ctgctctgat gccgccgtgt 11460 tccggctgtc agcgcagggg cgcccggttc tttttgtcaa gaccgacctg tccggtgccc 11520 tgaatgaact gcaggacgag gcagcgcggc tatcgtggct ggccacgacg ggcgttcctt 11580 gcgcagctgt gctcgacgtt gtcactgaag cgggaaggga ctggctgcta ttgggcgaag 11640 tgccggggca ggatctcctg tcatctcacc ttgctcctgc cgagaaagta tccatcatgg 11700 ctgatgcaat gcggcggctg catacgcttg atccggctac ctgcccattc gaccaccaag 11760 cgaaacatcg catcgagcga gcacgtactc ggatggaagc cggtcttgtc gatcaggatg 11820 atctggacga agagcatcag gggctcgcgc cagccgaact gttcgccagg ctcaaggcgc 11880 gca.tgcccga cggcgatgat ctcgtcgtga cccatggcga tgcctgcttg ccgaatatca 11940 tggtggaaaa tggccgcttt tctggattca tcgactgtgg ccggctgggt gtggcggacc 12000 gctatcagga. catagcgttg gctacccgtg atattgctga agagcttggc ggcgaatggg 12060 ctgaccgctt cctcgtgctt tacggtatcg ccgctcccga ttcgcagcgc atcgccttct 12120
[0151] atcgccttct tgacgagttc ttctgagcgg gactctgggg ttcgaaatga ccgaccaagc 12180 gacgcccaac ctgccatcac gagatttcga ttccaccgcc gccttctatg aaaggttggg 12240 cttcggaatc gttttccggg acgccggctg gatgatcctc cagcgcgggg atctcatgct 12300 ggagttcttc gcccacggga. tctxtgcgga acaggcggtc gaaggtgccg atatcattac 12360 gacagcaacg gccgacaagc acaacgccac gatcctgagc gacaatatga,tcgggcccgg 12420 cgtccacatc aacggcgtcg gcggcgactg cccaggcaag accgagatgc accgcgatat 12480 cttgctgcgt tcggatattt tcgtggagtt cccgccacag acccggatga iccccgatcg 12540 ttcaaacatt tggcaataaa gtttcttaag attgaatcct gttgccggtc ttgcgatgat 12600 tatcatataa tttctgttga attacgttaa gcatgtaata attaacatgt aatgcatgac 12660 gttatttatg agatgggttt ttatgattag agtcccgcaa ttatacattt aatacgcgat 12720 agaaaacaaa atatagcgcg caaactagga taaattatcg cgcgcggtgt catctatgtt 12780 actagatcgg gcctcctgtc aatgctggcg gcggctctgg tggtggttct ggtggcggct 12840 ctgagggtgg Lggctxtgag ggtggcggtt ctgagggtgg cggctctgag ggaggcggU 12900 ccggtggtgg
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